Detalles de la búsqueda
1.
Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity.
Int J Toxicol
; 42(1): 19-36, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36523256
2.
A systematic approach to evaluate plausible modes of actions for mouse lung tumors in mice exposed to 4-methylimidozole.
Regul Toxicol Pharmacol
; 124: 104977, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34174380
3.
A toxicogenomic approach for the risk assessment of the food contaminant acetamide.
Toxicol Appl Pharmacol
; 388: 114872, 2020 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31881176
4.
The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay.
Toxicol Appl Pharmacol
; 387: 114774, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31783037
5.
An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis.
Toxicol Appl Pharmacol
; 355: 112-126, 2018 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29782964
6.
Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment.
Regul Toxicol Pharmacol
; 96: 153-166, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29777725
7.
Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures.
Toxicol Appl Pharmacol
; 335: 28-40, 2017 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28951217
8.
Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver.
Toxicol Appl Pharmacol
; 332: 149-158, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28392392
9.
Multiple receptors shape the estrogen response pathway and are critical considerations for the future of in vitro-based risk assessment efforts.
Crit Rev Toxicol
; 47(7): 564-580, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28675057
10.
Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity.
Arch Toxicol
; 91(4): 1749-1762, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27592001
11.
Pathway Based Toxicology and Fit-for-Purpose Assays.
Adv Exp Med Biol
; 856: 205-230, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27671724
12.
Identification of a tissue-selective heat shock response regulatory network.
PLoS Genet
; 9(4): e1003466, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23637632
13.
Using gene expression profiling to evaluate cellular responses in mouse lungs exposed to V2O5 and a group of other mouse lung tumorigens and non-tumorigens.
Regul Toxicol Pharmacol
; 73(1): 339-47, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26210822
14.
Integrating gene expression and splicing dynamics across dose-response oxidative modulators.
Front Genet
; 15: 1389095, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38846964
15.
Macro-level modeling of the response of C. elegans reproduction to chronic heat stress.
PLoS Comput Biol
; 8(1): e1002338, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22291584
16.
Physically grounded approach for estimating gene expression from microarray data.
Proc Natl Acad Sci U S A
; 107(31): 13690-5, 2010 Aug 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-20643961
17.
Beyond pharmaceuticals: Fit-for-purpose new approach methodologies for environmental cardiotoxicity testing.
ALTEX
; 40(1): 103-116, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35648122
18.
Biological system considerations for application of toxicogenomics in next-generation risk assessment and predictive toxicology.
Toxicol In Vitro
; 80: 105311, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35038564
19.
NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene.
Toxicology
; 481: 153340, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36183849
20.
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation.
Front Toxicol
; 4: 894569, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35573278