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1.

A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ release in muscle fibers of Y522S RyR1 knock-in mice.

Andronache, Zoita; Hamilton, Susan L; Dirksen, Robert T; Melzer, Werner.

Proc Natl Acad Sci U S A ; 106(11): 4531-6, 2009 Mar 17.

Artículo en Inglés | MEDLINE | ID: mdl-19246389

2.

Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1.

Yamaguchi, Naohiro; Prosser, Benjamin L; Ghassemi, Farshid; Xu, Le; Pasek, Daniel A; Eu, Jerry P; Hernández-Ochoa, Erick O; Cannon, Brian R; Wilder, Paul T; Lovering, Richard M; Weber, David; Melzer, Werner; Schneider, Martin F; Meissner, Gerhard.

Am J Physiol Cell Physiol ; 300(5): C998-C1012, 2011 May.

Artículo en Inglés | MEDLINE | ID: mdl-21289290

3.

When sparks get old.

Melzer, Werner.

J Cell Biol ; 174(5): 613-4, 2006 Aug 28.

Artículo en Inglés | MEDLINE | ID: mdl-16943178

4.

S100A1 promotes action potential-initiated calcium release flux and force production in skeletal muscle.

Prosser, Benjamin L; Hernández-Ochoa, Erick O; Lovering, Richard M; Andronache, Zoita; Zimmer, Danna B; Melzer, Werner; Schneider, Martin F.

Am J Physiol Cell Physiol ; 299(5): C891-902, 2010 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-20686070

5.

Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells.

Lanner, Johanna T; Bruton, Joseph D; Assefaw-Redda, Yohannes; Andronache, Zoita; Zhang, Shi-Jin; Severa, Denise; Zhang, Zhi-Bin; Melzer, Werner; Zhang, Shi-Li; Katz, Abram; Westerblad, Håkan.

FASEB J ; 23(6): 1728-38, 2009 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-19141536

6.

Functional characterization of ryanodine receptor (RYR1) sequence variants using a metabolic assay in immortalized B-lymphocytes.

Zullo, Alberto; Klingler, Werner; De Sarno, Claudia; Ferrara, Marina; Fortunato, Giuliana; Perrotta, Giuseppa; Gravino, Elvira; Di Noto, Rosella; Lehmann-Horn, Frank; Melzer, Werner; Salvatore, Francesco; Carsana, Antonella.

Hum Mutat ; 30(4): E575-90, 2009 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-19191333

7.

Local calcium signals induced by hyper-osmotic stress in mammalian skeletal muscle cells.

Apostol, Simona; Ursu, Daniel; Lehmann-Horn, Frank; Melzer, Werner.

J Muscle Res Cell Motil ; 30(3-4): 97-109, 2009.

Artículo en Inglés | MEDLINE | ID: mdl-19437123

8.

No voltage change at skeletal muscle SR membrane during Ca²⁺ release-just Mermaids on acid.

Melzer, Werner.

J Gen Physiol ; 150(8): 1055-1058, 2018 08 06.

Artículo en Inglés | MEDLINE | ID: mdl-29970411

9.

Voltage modulates halothane-triggered Ca²⁺ release in malignant hyperthermia-susceptible muscle.

Zullo, Alberto; Textor, Martin; Elischer, Philipp; Mall, Stefan; Alt, Andreas; Klingler, Werner; Melzer, Werner.

J Gen Physiol ; 150(1): 111-125, 2018 01 02.

Artículo en Inglés | MEDLINE | ID: mdl-29247050

10.

Loss of S100A1 expression leads to Ca²⁺ release potentiation in mutant mice with disrupted CaM and S100A1 binding to CaMBD2 of RyR1.

Hernández-Ochoa, Erick O; Melville, Zephan; Vanegas, Camilo; Varney, Kristen M; Wilder, Paul T; Melzer, Werner; Weber, David J; Schneider, Martin F.

Physiol Rep ; 6(15): e13822, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-30101473

11.

From α1s splicing to Î³1 function: A new twist in subunit modulation of the skeletal muscle L-type Ca2+ channel.

Melzer, Werner.

J Gen Physiol ; 154(9)2022 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-35674662

12.

The Ca²⁺ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance.

Dayal, Anamika; Schrötter, Kai; Pan, Yuan; Föhr, Karl; Melzer, Werner; Grabner, Manfred.

Nat Commun ; 8(1): 475, 2017 09 07.

Artículo en Inglés | MEDLINE | ID: mdl-28883413

13.

Passive muscle stiffness may be influenced by active contractility of intramuscular connective tissue.

Schleip, Robert; Naylor, Ian L; Ursu, Daniel; Melzer, Werner; Zorn, Adjo; Wilke, Hans-Joachim; Lehmann-Horn, Frank; Klingler, Werner.

Med Hypotheses ; 66(1): 66-71, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16209907

14.

Fast-to-Slow Transition of Skeletal Muscle Contractile Function and Corresponding Changes in Myosin Heavy and Light Chain Formation in the R6/2 Mouse Model of Huntington's Disease.

Hering, Tanja; Braubach, Peter; Landwehrmeyer, G Bernhard; Lindenberg, Katrin S; Melzer, Werner.

PLoS One ; 11(11): e0166106, 2016.

Artículo en Inglés | MEDLINE | ID: mdl-27820862

15.

Altered inactivation of Ca2+ current and Ca2+ release in mouse muscle fibers deficient in the DHP receptor gamma1 subunit.

Ursu, Daniel; Schuhmeier, Ralph Peter; Freichel, Marc; Flockerzi, Veit; Melzer, Werner.

J Gen Physiol ; 124(5): 605-18, 2004 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-15504904

16.

ECC meets CEU-New focus on the backdoor for calcium ions in skeletal muscle cells.

Melzer, Werner.

J Gen Physiol ; 152(10)2020 10 05.

Artículo en Inglés | MEDLINE | ID: mdl-32851409

17.

Altered Ca(2+) signaling in skeletal muscle fibers of the R6/2 mouse, a model of Huntington's disease.

Braubach, Peter; Orynbayev, Murat; Andronache, Zoita; Hering, Tanja; Landwehrmeyer, Georg Bernhard; Lindenberg, Katrin S; Melzer, Werner.

J Gen Physiol ; 144(5): 393-413, 2014 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-25348412

18.

Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum.

Loy, Ryan E; Orynbayev, Murat; Xu, Le; Andronache, Zoita; Apostol, Simona; Zvaritch, Elena; MacLennan, David H; Meissner, Gerhard; Melzer, Werner; Dirksen, Robert T.

J Gen Physiol ; 137(1): 43-57, 2011 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-21149547

19.

Skeletal muscle fibers: Inactivated or depleted after long depolarizations?

Melzer, Werner.

J Gen Physiol ; 141(5): 517-20, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23630336

20.

The auxiliary subunit gamma 1 of the skeletal muscle L-type Ca2+ channel is an endogenous Ca2+ antagonist.

Andronache, Zoita; Ursu, Daniel; Lehnert, Simone; Freichel, Marc; Flockerzi, Veit; Melzer, Werner.

Proc Natl Acad Sci U S A ; 104(45): 17885-90, 2007 Nov 06.

Artículo en Inglés | MEDLINE | ID: mdl-17978188

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ release in muscle fibers of Y522S RyR1 knock-in mice.

Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1.

When sparks get old.

S100A1 promotes action potential-initiated calcium release flux and force production in skeletal muscle.

Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells.

Functional characterization of ryanodine receptor (RYR1) sequence variants using a metabolic assay in immortalized B-lymphocytes.

Local calcium signals induced by hyper-osmotic stress in mammalian skeletal muscle cells.

No voltage change at skeletal muscle SR membrane during Ca²⁺ release-just Mermaids on acid.

Voltage modulates halothane-triggered Ca²⁺ release in malignant hyperthermia-susceptible muscle.

Loss of S100A1 expression leads to Ca²⁺ release potentiation in mutant mice with disrupted CaM and S100A1 binding to CaMBD2 of RyR1.

From α1s splicing to Î³1 function: A new twist in subunit modulation of the skeletal muscle L-type Ca2+ channel.

The Ca²⁺ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance.

Passive muscle stiffness may be influenced by active contractility of intramuscular connective tissue.

Fast-to-Slow Transition of Skeletal Muscle Contractile Function and Corresponding Changes in Myosin Heavy and Light Chain Formation in the R6/2 Mouse Model of Huntington's Disease.

Altered inactivation of Ca2+ current and Ca2+ release in mouse muscle fibers deficient in the DHP receptor gamma1 subunit.

ECC meets CEU-New focus on the backdoor for calcium ions in skeletal muscle cells.

Altered Ca(2+) signaling in skeletal muscle fibers of the R6/2 mouse, a model of Huntington's disease.

Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum.

Skeletal muscle fibers: Inactivated or depleted after long depolarizations?

The auxiliary subunit gamma 1 of the skeletal muscle L-type Ca2+ channel is an endogenous Ca2+ antagonist.