1.
Org Biomol Chem
; 19(13): 2912-2916, 2021 04 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-33735355
RESUMEN
A modified Cp*Ru complex, equipped with a maleimide group, was covalently attached to a cysteine of an engineered variant of Ferric hydroxamate uptake protein component: A (FhuA). This synthetic metalloprotein catalyzed the intermolecular alkene-alkyne coupling of 3-butenol with 5-hexynenitrile. When compared with the protein-free Cp*Ru catalyst, the biohybrid catalyst produced the linear product with higher regioselectivity.