Primary subcutaneous zygomycosis due to Rhizopus oryzae in a 71-year-old man with normal immune status.

A case of primary subcutaneous zygomycosis due to Rhizopus oryzae is described in a 71-year-old man with normal immune status. Diagnosis was based on histological examination and culture of biopsy fragments from skin lesions. The patient recovered after itraconazole therapy (200 mg day(-1) for 60 days followed by 100 mg day(-1) for 45 days).