Detalles de la búsqueda
1.
A phase 1 study in healthy volunteers to investigate the safety, tolerability, and pharmacokinetics of VIR-2482: a monoclonal antibody for the prevention of severe influenza A illness.
Antimicrob Agents Chemother
; 68(4): e0127323, 2024 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38376227
2.
Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab.
N Engl J Med
; 385(21): 1941-1950, 2021 11 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34706189
3.
Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi® and Epclusa®.
Bioorg Med Chem Lett
; 29(16): 2415-2427, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31230974
4.
Drug-Drug Interaction Studies Between Hepatitis C Virus Antivirals Sofosbuvir/Velpatasvir and Boosted and Unboosted Human Immunodeficiency Virus Antiretroviral Regimens in Healthy Volunteers.
Clin Infect Dis
; 67(6): 934-940, 2018 08 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-29522076
5.
The Drug-Drug Interaction Potential of Antiviral Agents for the Treatment of Chronic Hepatitis C Infection.
Drug Metab Dispos
; 46(8): 1212-1225, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-29695614
6.
Sofosbuvir and Velpatasvir for the Treatment of Hepatitis C Virus in Patients Coinfected With Human Immunodeficiency Virus Type 1: An Open-Label, Phase 3 Study.
Clin Infect Dis
; 65(1): 6-12, 2017 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28369210
7.
Preclinical Pharmacokinetics and First-in-Human Pharmacokinetics, Safety, and Tolerability of Velpatasvir, a Pangenotypic Hepatitis C Virus NS5A Inhibitor, in Healthy Subjects.
Antimicrob Agents Chemother
; 61(5)2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28193657
8.
Sofosbuvir Plus Velpatasvir Combination Therapy for Treatment-Experienced Patients With Genotype 1 or 3 Hepatitis C Virus Infection: A Randomized Trial.
Ann Intern Med
; 163(11): 809-17, 2015 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26551263
9.
Modeling and Understanding Combination pMDI Formulations with Both Dissolved and Suspended Drugs.
Mol Pharm
; 12(9): 3455-67, 2015 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26258647
10.
Population pharmacokinetics and exposure-response analysis of a single dose of sotrovimab in the early treatment of patients with mild to moderate COVID-19.
CPT Pharmacometrics Syst Pharmacol
; 12(6): 853-864, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36922886
11.
Intramuscular vs Intravenous SARS-CoV-2 Neutralizing Antibody Sotrovimab for Treatment of COVID-19 (COMET-TAIL): A Randomized Noninferiority Clinical Trial.
Open Forum Infect Dis
; 10(8): ofad354, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37577112
12.
Antibody therapy reverses biological signatures of COVID-19 progression.
Cell Rep Med
; 3(8): 100721, 2022 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35977462
13.
Clinical and Preclinical Single-Dose Pharmacokinetics of VIR-2218, an RNAi Therapeutic Targeting HBV Infection.
Drugs R D
; 21(4): 455-465, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34741731
14.
Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model.
AAPS PharmSciTech
; 11(1): 168-73, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20101484
15.
Accounting for the effects of moderately increased pressure on the energetics of melting and solubility in metered dose inhalers.
Drug Dev Ind Pharm
; 34(9): 930-5, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18800253
16.
Pharmacokinetics and Safety of Velpatasvir and Sofosbuvir/Velpatasvir in Subjects with Hepatic Impairment.
Clin Pharmacokinet
; 57(11): 1449-1457, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29520729
17.
New analytical techniques to facilitate preformulation screening in propellant systems.
Int J Pharm
; 340(1-2): 223-9, 2007 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17498897
18.
Application of heated inlet extensions to the TSI 3306/3321 system: comparison with the Andersen cascade impactor and next generation impactor.
J Aerosol Med
; 19(4): 543-54, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-17196082
19.
Use of Multiple Probes to Assess Transporter- and Cytochrome P450-Mediated Drug-Drug Interaction Potential of the Pangenotypic HCV NS5A Inhibitor Velpatasvir.
Clin Pharmacokinet
; 55(5): 605-13, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26519191
20.
Effects of extreme temperatures on drug delivery of albuterol sulfate hydrofluoroalkane inhalation aerosols.
Am J Health Syst Pharm
; 62(21): 2271-7, 2005 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16239418