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1.
Sci Rep ; 10(1): 1965, 2020 02 06.
Artículo en Inglés | MEDLINE | ID: mdl-32029806

RESUMEN

We have investigated changes of western North Pacific land-falling tropical cyclone (TC) characteristics due to warmer climate conditions, using the pseudo-global-warming (PGW) technique. Historical simulations of three intense TCs making landfall in Pearl River Delta (PRD) were first conducted using the Weather Research and Forecasting (WRF) model. The same cases were then re-simulated by superimposing near- (2015-2039) and far- (2075-2099) future temperature and humidity changes onto the background climate; these changes were derived from the Coupled Model Intercomparison Project phase 5 (CMIP5) multi-model projections according to the Representative Concentration Pathway (RCP) 8.5 scenario. Peak intensities of TCs (maximum surface wind in their lifetimes) are expected to increase by ~ (3) 10% in the (near) far future. Further experiments indicate that surface warming alone acts to intensify TCs by enhancing sea surface heat flux, while warmer atmosphere acts in the opposite way by increasing the stability. In the far future, associated storm surges are also estimated to increase by about 8.5%, computed by the Sea, Lake, and Overland Surges from Hurricanes (SLOSH) model. Combined with sea level rise and estimated land vertical displacement, TC-induced storm tide affecting PRD will increase by ~1 m in the future 2075-2099 period.

2.
Medicine (Baltimore) ; 94(46): e2024, 2015 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-26579810

RESUMEN

Information on respiratory viruses in subtropical region is limited.Incidence, mortality, and seasonality of influenza (Flu) A/B, respiratory syncytial virus (RSV), adenovirus (ADV), and parainfluenza viruses (PIV) 1/2/3 in hospitalized patients were assessed over a 15-year period (1998-2012) in Hong Kong.Male predominance and laterally transversed J-shaped distribution in age-specific incidence was observed. Incidence of Flu A, RSV, and PIV decreased sharply from infants to toddlers; whereas Flu B and ADV increased slowly. RSV conferred higher fatality than Flu, and was the second killer among hospitalized elderly. ADV and PIV were uncommon, but had the highest fatality. RSV, PIV 2/3 admissions increased over the 15 years, whereas ADV had decreased significantly. A "high season," mainly contributed by Flu, was observed in late-winter/early-spring (February-March). The "medium season" in spring/summer (April-August) was due to Flu and RSV. The "low season" in late autumn/winter (October-December) was due to PIV and ADV. Seasonality varied between viruses, but predictable distinctive pattern for each virus existed, and temperature was the most important associating meteorological variable.Respiratory viruses exhibit strong sex- and age-predilection, and with predictable seasonality allowing strategic preparedness planning. Hospital-based surveillance is crucial for real-time assessment on severity of new variants.


Asunto(s)
Infecciones por Adenovirus Humanos/epidemiología , Hospitalización/estadística & datos numéricos , Gripe Humana/epidemiología , Infecciones por Paramyxoviridae/epidemiología , Infecciones por Virus Sincitial Respiratorio/epidemiología , Estaciones del Año , Salud Urbana/estadística & datos numéricos , Adolescente , Adulto , Distribución por Edad , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Femenino , Hong Kong/epidemiología , Humanos , Incidencia , Lactante , Recién Nacido , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Distribución por Sexo , Adulto Joven
3.
J Rheumatol ; 35(6): 1031-7, 2008 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-18398942

RESUMEN

OBJECTIVE: It is generally agreed that there is a seasonal variation in the prevalence of cutaneous manifestations of systemic lupus erythematosus (SLE). We investigated whether there is seasonal variation in the incidence of noncutaneous lupus flare in Hong Kong. METHODS: We reviewed all noncutaneous lupus flare in 222 consecutive patients with SLE followed in our clinic from 1995 to 2005. Specific organ involvement of each flare was reviewed. The variation in the prevalence of lupus flare by calendar month and the relation with climatic factors were determined. RESULTS: The total followup was 18,412 patient-months. In total, there were 313 episodes of noncutaneous flare recorded in 129 patients. There were more lupus flares in December and January [2.31 episodes, vs 1.58 episodes per 100 patient-months for other calendar months; relative risk (RR) 1.46, 95% CI 1.12-1.90, p = 0.004], and more flares of lupus nephritis in December and January (1.14 episodes, vs 0.60 episodes per 100 patient-months for other calendar months; RR 1.90, 95% CI 1.29-2.80, p = 0.001). There were more cases of membranous nephropathy in December and January (0.46 episode, vs 0.18 episode per 100 patient-months for other calendar months; RR 2.59, 95% CI 1.36-4.93, p = 0.0027), while the variation in prevalence of proliferative lupus nephritis was not statistically significant. There was also a significant U-shape correlation between the rate of lupus flare and the monthly average environmental temperature (r = 0.802, p = 0.0096), with higher flare rate at extremes of temperature. CONCLUSION: We found substantial seasonal variation in the incidence of noncutaneous flare in our SLE patients, with peak incidence in December and January. There was a U-shaped relation between environmental temperature and the prevalence of noncutaneous flare. Keeping a warm living environment and avoiding exposure to extremes of temperature may help to reduce flare for SLE patients in subtropical countries.


Asunto(s)
Clima , Lupus Eritematoso Sistémico/complicaciones , Estaciones del Año , Adulto , Femenino , Hong Kong , Humanos , Masculino , Índice de Severidad de la Enfermedad
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