[Serological Profiles of Hepatitis-B HBcAb-Positive Blood donors ]. / Perfiles serológicos de hepatitis B en donantes de sangre con anti-HBc reactivos.

OBJECTIVE: To assess the serological profiles for HBV in blood donors that were anti-HBc reactive and non-reactive to HBsAg in four Colombian cities. MATERIALS AND METHODS: A prospective transversal study was conducted during 17 months, applying a complete serological profile for HBV in samples from blood donors that were anti-HBc reactive and non-reactive to HBsAg, results were analyzed employing descriptive statistics using Microsoft Excel and Epiinfo V. 3.5.1. RESULTS: From donors reactive to anti-HBc, 75.0 % shown some additional infection marker for HBV. 1.3 % of blood donors had serological markers for chronical infection with hepatitis B, and a case had reactivity only for hepatitis B surface antigen (HBsAg). 6.1 % of donors showed a vaccination serological profile, only with reactivity to anti-HBsAg antibodies. CONCLUSIONS: With this study, anti-HBc blood screening importance was confirmed.

Perfiles serológicos de hepatitis B en donantes de sangre con anti-HBc reactivos / Serological profiles of hepatitis-B HBcAb-positive blood donors

Objetivo Determinar los perfiles serológicos para el virus de hepatitis B, en donantes de sangre anti-HBc reactivo y antígeno de superficie no reactivo, provenientes de cuatro ciudades del país Métodos Se realizó un estudio prospectivo transversal, durante un período de 17 meses, aplicando el perfil serológico completo de la hepatitis B, en muestras de donantes con anti-HBc reactivo y antígeno de superficie de hepatitis B no reactivo. Los resultados fueron analizados utilizando Microsoft® Excel y Epiinfo V 3.5.1. Resultados Se encontró que el 75 % de los donantes reactivos para anti-HBc en los bancos de sangre, presentaban algún marcador adicional de exposición para el VHB; el 1,3 % de los donantes presentaban marcadores serológicos de infección crónica por hepatitis B y un caso que resultó reactivo solamente para antígeno de superficie de hepatitis B. Se halló perfil de vacunación en el 6,1 % de donantes, que fueron reactivos solamente para anticuerpo contra antígeno de superficie.Conclusiones. Se ratifica la importancia de la tamización de anti-HBc, a los donantes de sangre...(AU)

To assess the serological profiles for HBV in blood donors that were anti-HBc reactive and non-reactive to HBsAg in four Colombian cities. Materials and Methods A prospective transversal study was conducted during 17 months, applying a complete serological profile for HBV in samples from blood donors that were anti-HBc reactive and non-reactive to HBsAg, results were analyzed employing descriptive statistics using Microsoft Excel and Epiinfo V. 3.5.1. Results From donors reactive to anti-HBc, 75.0 % shown some additional infection marker for HBV. 1.3 % of blood donors had serological markers for chronical infection with hepatitis B, and a case had reactivity only for hepatitis B surface antigen (HBsAg). 6.1 % of donors showed a vaccination serological profile, only with reactivity to anti-HBsAg antibodies. Conclusions With this study, anti-HBc blood screening importance was confirmed...(AU)