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Rom J Intern Med ; 61(3): 167-174, 2023 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-37389671

RESUMEN

Carcinomatosis of the bone marrow is a rare clinical condition characterized by diffuse tumor infiltration of the bone marrow accompanied by hematological abnormalities, including thrombotic microangiopathy (TMA) and disseminated intravascular coagulation (DIC). In patients with gastric carcinoma, this association is infrequent. Below we present a case of a 19-year-old female patient with no known pathological history who presented with upper digestive tract bleeding. Upon examination, anemia and thrombocytopenia were documented, with schistocytes in the peripheral blood smear and prolonged coagulation times. Endoscopic studies indicated a lesion in the Borrmann IV gastric body, and the bone marrow biopsy showed the presence of signet ring cells. Because there was no possibility of systemic therapy, the patient died during hospitalization. This case contributes to the medical literature by describing an unusual presentation of a very frequent pathology.


Asunto(s)
Adenocarcinoma , Carcinoma , Coagulación Intravascular Diseminada , Neoplasias Gástricas , Microangiopatías Trombóticas , Femenino , Humanos , Adulto Joven , Adulto , Coagulación Intravascular Diseminada/etiología , Médula Ósea/patología , Adenocarcinoma/complicaciones , Microangiopatías Trombóticas/complicaciones , Microangiopatías Trombóticas/diagnóstico , Carcinoma/complicaciones , Carcinoma/tratamiento farmacológico , Carcinoma/patología , Neoplasias Gástricas/complicaciones
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