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1.

Long-range DNA interactions at the IL-1/IL-36/IL-37 gene cluster (2q13) are induced by activation of monocytes.

Sharaf, Nazar; Nicklin, Martin J; di Giovine, Francesco S.

Cytokine ; 68(1): 16-22, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24787052

2.

High SARS-CoV-2 incidence and asymptomatic fraction during Delta and Omicron BA.1 waves in The Gambia.

Jarju, Sheikh; Wenlock, Rhys D; Danso, Madikoi; Jobe, Dawda; Jagne, Ya Jankey; Darboe, Alansana; Kumado, Michelle; Jallow, Yusupha; Touray, Mamlie; Ceesay, Ebrima A; Gaye, Hoja; Gaye, Biran; Tunkara, Abdoulie; Kandeh, Sheriff; Gomes, Marie; Sylva, Ellen Lena; Toure, Fatoumata; Hornsby, Hailey; Lindsey, Benjamin B; Nicklin, Martin J; Sayers, Jon R; Sesay, Abdul K; Kucharski, Adam; Hodgson, David; Kampmann, Beate; de Silva, Thushan I.

Nat Commun ; 15(1): 3814, 2024 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-38714680

3.

Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration.

Phillips, Kate Louise Eve; Jordan-Mahy, Nikki; Nicklin, Martin J H; Le Maitre, Christine Lyn.

Ann Rheum Dis ; 72(11): 1860-7, 2013 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-23396662

4.

Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy.

Williams, Daniel M; Hornsby, Hailey R; Shehata, Ola M; Brown, Rebecca; Gallis, Marta; Meardon, Naomi; Newman, Thomas A H; Plowright, Megan; Zafred, Domen; Shun-Shion, Amber S M; Hodder, Anthony J; Bliss, Deepa; Metcalfe, Andrew; Edgar, James R; Gordon, David E; Sayers, Jon R; Nicklin, Martin J; Carroll, Miles; Collini, Paul J; Brown, Stephen; de Silva, Thushan I; Peden, Andrew A.

iScience ; 26(7): 107056, 2023 Jul 21.

Artículo en Inglés | MEDLINE | ID: mdl-37346049

5.

Interleukin-1ß regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages.

Marriott, Helen M; Gascoyne, Kate A; Gowda, Ravi; Geary, Ian; Nicklin, Martin J H; Iannelli, Francesco; Pozzi, Gianni; Mitchell, Timothy J; Whyte, Moira K B; Sabroe, Ian; Dockrell, David H.

Infect Immun ; 80(3): 1140-9, 2012 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-22158745

6.

Impact of IL-1 signalling on experimental uveitis and arthritis.

Planck, Stephen R; Woods, April; Clowers, Jenna S; Nicklin, Martin J; Rosenbaum, James T; Rosenzweig, Holly L.

Ann Rheum Dis ; 71(5): 753-60, 2012 May.

Artículo en Inglés | MEDLINE | ID: mdl-22267332

7.

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis.

Abdollahi-Roodsaz, Shahla; Joosten, Leo A B; Koenders, Marije I; Devesa, Isabel; Roelofs, Mieke F; Radstake, Timothy R D J; Heuvelmans-Jacobs, Marleen; Akira, Shizuo; Nicklin, Martin J H; Ribeiro-Dias, Fátima; van den Berg, Wim B.

J Clin Invest ; 118(1): 205-16, 2008 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-18060042

8.

ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin.

Partridge, Lynda J; Urwin, Lucy; Nicklin, Martin J H; James, David C; Green, Luke R; Monk, Peter N.

Cells ; 10(6)2021 06 07.

Artículo en Inglés | MEDLINE | ID: mdl-34200372

9.

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust.

Colton, Hayley; Hodgson, David; Hornsby, Hailey; Brown, Rebecca; Mckenzie, Joanne; Bradley, Kirsty L; James, Cameron; Lindsey, Benjamin B; Birch, Sarah; Marsh, Louise; Wood, Steven; Bayley, Martin; Dickson, Gary; James, David C; Nicklin, Martin J; Sayers, Jon R; Zafred, Domen; Rowland-Jones, Sarah L; Kudesia, Goura; Kucharski, Adam; Darton, Thomas C; de Silva, Thushan I; Collini, Paul J.

Wellcome Open Res ; 6: 220, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-35600250

10.

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust.

Hodgson, David; Colton, Hayley; Hornsby, Hailey; Brown, Rebecca; Mckenzie, Joanne; Bradley, Kirsty L; James, Cameron; Lindsey, Benjamin B; Birch, Sarah; Marsh, Louise; Wood, Steven; Bayley, Martin; Dickson, Gary; James, David C; Nicklin, Martin J H; Sayers, Jon R; Zafred, Domen; Rowland-Jones, Sarah L; Kudesia, Goura; Kucharski, Adam; Darton, Thomas C; de Silva, Thushan I; Collini, Paul J.

medRxiv ; 2021 Jul 08.

Artículo en Inglés | MEDLINE | ID: mdl-34268521

11.

Finally, function for "IL-1Fs".

Nicklin, Martin J H.

Blood ; 118(22): 5713-4, 2011 Nov 24.

Artículo en Inglés | MEDLINE | ID: mdl-22123902

12.

Evidence that all Sorsby's fundus dystrophy mutations cause TIMP3 dimerization resulting in impaired inhibition of VEGFR2.

Alsaffar, Fatimah A; Mujamammi, Ahmed H; Aldughaim, Mohammed S K; Nicklin, Martin J H; Barker, Michael D.

Genes Dis ; 10(1): 45-47, 2023 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-37013036

13.

Elastic-vessel arteritis in interleukin-1 receptor antagonist-deficient mice involves effector Th1 cells and requires interleukin-1 receptor.

Shepherd, Joanna; Nicklin, Martin J H.

Circulation ; 111(23): 3135-40, 2005 Jun 14.

Artículo en Inglés | MEDLINE | ID: mdl-15939811

14.

Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.

Somm, Emmanuel; Henrichot, Elvire; Pernin, Agnès; Juge-Aubry, Cristiana E; Muzzin, Patrick; Dayer, Jean-Michel; Nicklin, Martin J H; Meier, Christoph A.

Diabetes ; 54(12): 3503-9, 2005 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-16306368

15.

Psoriasis-like cutaneous inflammation in mice lacking interleukin-1 receptor antagonist.

Shepherd, Joanna; Little, Matthew C; Nicklin, Martin J H.

J Invest Dermatol ; 122(3): 665-9, 2004 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-15086551

16.

Intracellular function of interleukin-1 receptor antagonist in ischemic cardiomyocytes.

Vecile, Elena; Dobrina, Aldo; Salloum, Fadi N; Van Tassell, Benjamin W; Falcione, Antonella; Gustini, Edoardo; Secchiero, Samuele; Crovella, Sergio; Sinagra, Gianfranco; Finato, Nicoletta; Nicklin, Martin J; Abbate, Antonio.

PLoS One ; 8(1): e53265, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23308180

17.

Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis.

Mohanty, Sindhu T; Kottam, Lucksy; Gambardella, Alessandra; Nicklin, Martin J; Coulton, Les; Hughes, David; Wilson, Anthony G; Croucher, Peter I; Bellantuono, Ilaria.

Arthritis Res Ther ; 12(4): R149, 2010.

Artículo en Inglés | MEDLINE | ID: mdl-20649960

18.

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice.

Koenders, Marije I; Devesa, Isabel; Marijnissen, Renoud J; Abdollahi-Roodsaz, Shahla; Boots, Annemieke M H; Walgreen, Birgitte; di Padova, Franco E; Nicklin, Martin J H; Joosten, Leo A B; van den Berg, Wim B.

Arthritis Rheum ; 58(11): 3461-70, 2008 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-18975337

19.

The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes.

Magne, David; Palmer, Gaby; Barton, Jenny L; Mézin, Francoise; Talabot-Ayer, Dominique; Bas, Sylvette; Duffy, Trevor; Noger, Marcus; Guerne, Pierre-Andre; Nicklin, Martin J H; Gabay, Cem.

Arthritis Res Ther ; 8(3): R80, 2006.

Artículo en Inglés | MEDLINE | ID: mdl-16646978

20.

Toll-like receptor 2 and 4 (TLR2 and TLR4) agonists differentially regulate secretory interleukin-1 receptor antagonist gene expression in macrophages.

Carl, Virginia S; Brown-Steinke, Kathleen; Nicklin, Martin J H; Smith, Michael F.

J Biol Chem ; 277(20): 17448-56, 2002 May 17.

Artículo en Inglés | MEDLINE | ID: mdl-11877429

BVS CLAP/SMR-OPS/OMS

Centro Latinoamericano de Perinatología, Salud de la Mujer y Reproductiva

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Long-range DNA interactions at the IL-1/IL-36/IL-37 gene cluster (2q13) are induced by activation of monocytes.

High SARS-CoV-2 incidence and asymptomatic fraction during Delta and Omicron BA.1 waves in The Gambia.

Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration.

Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy.

Interleukin-1ß regulates CXCL8 release and influences disease outcome in response to Streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages.

Impact of IL-1 signalling on experimental uveitis and arthritis.

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis.

ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin.

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust.

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust.

Finally, function for "IL-1Fs".

Evidence that all Sorsby's fundus dystrophy mutations cause TIMP3 dimerization resulting in impaired inhibition of VEGFR2.

Elastic-vessel arteritis in interleukin-1 receptor antagonist-deficient mice involves effector Th1 cells and requires interleukin-1 receptor.

Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.

Psoriasis-like cutaneous inflammation in mice lacking interleukin-1 receptor antagonist.

Intracellular function of interleukin-1 receptor antagonist in ischemic cardiomyocytes.

Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis.

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice.

The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes.

Toll-like receptor 2 and 4 (TLR2 and TLR4) agonists differentially regulate secretory interleukin-1 receptor antagonist gene expression in macrophages.