Is there a correlation between pelvic incidence and orientation of the acetabulum? An analysis based on a three-dimensional statistical model of the pelvic ring.

The pelvic ring is a complex anatomical structure building up the connection between the trunk and the legs. Whilst there is a broad discussion in the literature about the dynamic interaction between spine, pelvis and the hip joints, there is still little information about the relation and interaction of the constant pelvic parameters. Based on a three-dimensional (3D) statistical model consisting of 150 uninjured and bony healthy pelves (100 Europeans, 50 Japanese; 81 males, 69 females; average age 74.3 years ± 17.5 years) an evaluation of pelvic incidence (PI) and acetabular orientation in anteversion and inclination was performed and potential correlations of these intraindividual constant parameters were investigated. Pelvic incidence is defined as the angle between the perpendicular to the sacral plate at its midpoint and the line connecting this point to the middle axis of the femoral heads. Acetabular anteversion is defined as the angle between the perpendicular to the best-fit plane on the acetabular rim and the coronal plane measured in strict lateral view. Acetabular inclination is defined as the angle between the perpendicular to the best-fit plane on the acetabular rim and the sagittal plane in strict frontal view. Data were further analysed with regard to different subgroup's age, sex and ethnicity. A positive correlation between PI and acetabular anteversion could be demonstrated. Further, PI and also the acetabular parameters anteversion and inclination were found to be significantly higher in the European individuals than in the Asian. The results of the present study demonstrate a relation between the anatomical configuration of the constant pelvic parameters building up the connection points to the next proximal respectively caudal skeleton section. The findings might lead to more comprehensive treatment strategies in case of trauma or degenerative pathologies of the pelvis in the future.

Asymmetry of the pelvic ring evaluated by CT-based 3D statistical modeling.

The human pelvis is a complex anatomical structure that consists of the innominate bones, sacrum and coccyx to form the pelvic ring. Even though considered to be a symmetric entity, asymmetry of the pelvic ring (APR) might occur to alter its anatomy, function, or biomechanics or to impact assessment and treatment of clinical cases. APR and its assessment is complicated by the intricate anatomy of the pelvic ring. There is only limited information and understanding about APR with no established evaluation methods existing. The objective of the present study was to adopt CT-based 3D statistical modeling and analysis to assess APR within the complex anatomy of the pelvic ring. We were interested to establish a better understanding of APR with knowledge and applications transferred to human anatomy, related research, and development subjects and to clinical settings. A series of 150 routine, clinical, pelvic CT protocols of European and Asian males and females (64 ± 15 (20-90) years old) were post-processed to compute gender- and ancestry-specific 3D statistical models of the pelvic ring. Evaluations comprised principal component analysis (PCA) that included size, shape, and asymmetry patterns and their variations to be assessed. Four different CT-based 3D statistical models of the entire pelvic ring were computed according to the gender and ancestry specific groups. PCA mainly displayed size and shape variations. Examination of additional PCA modes permitted six distinct asymmetry patterns to be identified. They were located at the sacrum, iliac crest, pelvic brim, pubic symphysis, inferior pubic ramus, and near to the acetabulum. Accordingly, the pelvic ring demonstrated not to be entirely symmetric. Assessment of its asymmetry proved to be a challenging task. Using CT-based 3D statistical modeling and PCA, we identified six distinct APRs that were located at different anatomical regions. These regions are more prone to APRs than other sites. Minor asymmetry patterns have to be distinguished from the distinct APRs. Side differences with regard to size, shape, and/or position require to be taken into account. APRs may be due different load mechanisms applied via spine or lower extremity or locally. There is a need for simpler and efficient, yet reliable methods to be routinely transferred to human anatomy, related research, and development subjects and to clinical settings.

3D statistical model of the pelvic ring - a CT-based statistical evaluation of anatomical variation.

The pelvic ring is a highly complex construct with a central role for human stability and mobility. The observable interindividual differences in skeletal anatomy are caused by anatomical variation in the innominate bones as well as the sacrum, further to differences in the spatial arrangement of these bones to each other. The aim of this study was to generate a 3D statistical model of the entire pelvic ring in order to analyse the observed interindividual differences and anatomical variation. A series of 50 anonymized pelvic CT scans of uninjured Japanese adults [30 males, 20 females, average age of 74.9 years, standard deviation (SD) 16.9 years] were processed and analysed, resulting in a 3D statistical overall mean model and separate male and female mean models. Principal component analysis (PCA) of the overall statistical model predominantly showed size variation (20.39%) followed by shape variation (14.13%), and a variation of the spatial arrangement of the sacrum to the innominate bones in different anatomical peculiarities (11.39 and 8.85%). In addition, selected internal and external pelvic parameters were manually measured with the objective of further evaluating and quantifying the observed interindividual as well as the known sex-specific differences. A separate statistical model of the grey value distribution based on the given Hounsfield unit (HU) values was calculated for assessing bone mass distribution, thus an indication of bone quality utilizing grey values as a quantitative description of radiodensity was obtained. A consistent pattern of grey value distribution was shown, with the highest grey values observed between the sacro-iliac joint and the acetabulum along the pelvic brim. Low values were present in the sacral ala, in the area of the iliac fossa as well as in the pubic rami next to the symphysis. The present model allows a differentiated analysis of the observed interindividual variation of the pelvic ring and an evaluation of the grey value distribution therein. Besides providing a better understanding of anatomical variation, this model could be also used as a helpful tool for educational purposes, preoperative planning and implant design.

Computerized anatomy of the distal radius and its relevance to volar plating, research, and teaching.

Distal radius fractures are common and fracture patterns and fixation can be complex. Computerized anatomy evaluation (CAE) might offer non-invasive and enhanced anatomy assessment that might help with implant selection and placement and screw length determination. Our goal was to test the accuracy of two CAE methods for anatomical volar plate positioning and screw lengths measurement of the distal radius. We included 56 high-resolution peripheral quantitative computed tomography scans of intact, human distal radii. Plates were placed manually onto 3D printed models (method 1), which was compared with automated computerized plate placement onto the 3D computer models (method 2). Subsequently, screw lengths were determined digitally for both methods. Screw lengths evaluations were compared via Bland-Altman plots. Both CAE methods resulted in identical volar plate selection and in anatomical plate positioning. For screw length the concordance correlation coefficient was ≥0.91, the location shift ≤0.22 mm, and the scale shift ≤0.16. The differences were smaller than ±1 mm in all samples. Both CAE methods allow for comparable plate positioning and subsequent screw length measurement in distal radius volar plating. Both can be used as a non-invasive teaching environment for volar plate fixation. Method 2 even offers fully computerized assessments. Future studies could compare our models to other anatomical areas, post-operative volar plate positioning, and model performance in actual distal radius fracture instead of intact radii. Clin. Anat. 32:361-368, 2019. © 2018 The Authors. Clinical Anatomy published by Wiley Periodicals, Inc. on behalf of American Association of Clinical Anatomists.

Space available for trans-sacral implants to treat fractures of the pelvis assessed by virtual implant positioning.

INTRODUCTION: The use of trans-sacral implants to treat fractures of the sacrum is limited by the variable pelvic anatomy. We were interested in how many trans-sacral implants can be placed per pelvis? If a trans-sacral implant cannot be placed in S1, where is the cortex perforated, and is the use of sacroiliac screws safe in these pelves? MATERIALS AND METHODS: 3D pelvic models were created from CT scans of 156 individuals without fractures (92 European and 64 Japanese, 79 male and 77 female, mean age 66.7 ± 13.7 years). Trans-sacral implants with a diameter of 7.3 mm were positioned virtually with and without a surrounding safe zone of 12 mm diameter. RESULTS: Fifty-one percent of pelves accommodated trans-sacral implants in S1 with a safe zone. Twenty-two percent did not offer enough space in S1 for an implant even when ignoring the safe zone. Every pelvis had sufficient space for a trans-sacral implant in S2, in 78% including a safe zone as well. In S1, implant perforation was observed in the sacral ala and iliac fossa in 69%, isolated iliac fossa perforation in 23% and perforation of the sacral ala in 8%. Bilateral sacroiliac screw placement was always possible in S1. CONCLUSIONS: The use of trans-sacral implants in S1 requires meticulous preoperative planning to avoid injury of neurovascular structures. S2 more consistently offers space for trans-sacral implants.

Fragility fractures of the sacrum occur in elderly patients with severe loss of sacral bone mass.

INTRODUCTION: Patients suffering from osteoporosis-associated fragility fractures of the sacrum (FFS; also termed sacral insufficiency fractures) are increasingly observed. They have typical fracture patterns with fracture lines located in the sacral ala. When treating these patients operatively, iliosacral screw loosening is not uncommon. We aimed to study the sacral bone mass in patients presenting with a FFS using 3D statistical models. MATERIALS AND METHODS: 3D models of averaged Hounsfield units (HU) were generated based on CT scans from 13 patients with a unilateral FFS (mean age 79.6 years; 11 females, 2 males). The control group without fractures consisted of 28 males and 32 females (mean age of 68.3 years). A virtual bone probe along the trans-sacral corridors S1 and S2 was taken. RESULTS: The bone mass distribution in the fractured sacra was similar to the control group, however, with overall lower HU. Large zones of negative HU were located in the sacral ala. In the fractured sacra, the HU in the sacral ala was significantly lower on the non-injured side when comparing to the fractured side (p < 0.001) as well as compared to the non-fractured group (p < 0.001). Low bone mass was observed in sacral body S1 (40 HU) and S2 (20 HU). CONCLUSIONS: The extensive area of negative HU may explain the fracture location in the sacral ala. The low HU in the sacral bodies advocates the use of trans-sacral implants or augmented iliosacral screws to enhance the strength of fracture fixation. The increased HU in the fractured ala could be explained by fracture-asssociated hemorrhage and can be used as a diagnostic tool.

Bone Mass Distribution of the Distal Tibia in Normal, Osteopenic, and Osteoporotic Conditions: An Ex Vivo Assessment Using HR-pQCT, DXA, and Computational Modelling.

Osteoporosis leads to bone loss and structural deterioration, which increase the risk of fractures. The aim of this study was to characterize the three-dimensional (3D) bone mass distributions of the distal tibia in normal, osteopenic, and osteoporotic conditions. High-resolution peripheral quantitative computed tomography (HR-pQCT) of the 33 % of the distal tibia and local dual-energy X-ray absorptiometry were applied to 53 intact, fresh-frozen tibiae. The HR-pQCTs were graded to assign local T-scores and merged into three equally sized average normal, osteopenic, and osteoporotic surface models. Volumetric bone mineral density (vBMD) was determined using categorized T-scores, volumetric visualization, and virtual bore probes at the dia-, meta-, and epiphyseal sites (T-DIA, T-META, and T-EPI). We observed a distinct 3D bone mass distribution that was gradually uninfluenced by T-score categories. T-DIA was characterized by the lowest bone mass located in the medullary cavity and a wide homogenous cortex containing the maximum vBMD. The T-META showed decreased cortical thickness and maximal vBMD. At the T-EPI, the relatively low vBMD of the mostly trabecular bone was similar to the maximal cortical vBMD in this sub-region. Four trabecular regions of low bone mass were identified in the recesses. The bone content gradually decreased at all sites, whereas the pattern of bone mass distribution remained essentially unchanged, with the exception of disproportionate losses at T-DIA, T-META, and T-EPI that consistently showed increased endocortical, intracortical, and trabecular bone loss. Extra information can be obtained from the specific pattern of bone mass distribution, potential disproportionate bone losses, and method used.

Anatomical background for the development of preformed cranioplasty implants.

Preformed cranioplasty implants form a new concept of implants to repair relatively large-sized calvarial defects. They could offer an alternative treatment to manually molded cranioplasty, and to flat or patient specific implants, while still achieving a satisfactory clinical result.We report on 3D statistical modeling and analysis performed in 80 clinical CT data of adult European Whites with unaffected calvarial bones to establish an anatomical background for the development of preformed alloplastic cranioplasty implants.Most size and shape (=form) variation was observed bilateral symmetrically in the central temporal region, showing up to 26.8 mm variation and 9.4 mm standard deviation from the mean form. Large deviation was also observed in the central lower forehead, in the central occipital region at the protuberantia occipitalis externa and laterally to it. An intermediate variation was detected at the transition area from the temporal to other regions, as well as in the frontal and occipital area. The cranial roof, the temporal fossa, and the nuchal region exhibited the lowest variability with a standard deviation of about 4 mm. Principal components analysis revealed no relevant shape but a significant size difference between genders. Size contributed to 24.4% of the overall form variability. The mean surface area difference between genders was 67 cm.The size and number of implant forms required have to be referred to the relatively large anatomical variation experienced, and also to considerations related to implant location, design, and material. A rigid material is considered to significantly increase the number of implants forms, especially when repairing relatively large-sized defects.

Anatomy-based surgical concepts for individualized orbital decompression surgery in graves orbitopathy. II. Orbital rim position and angulation.

PURPOSE: To detect anatomical conditions that may benefit from an orbital rim advancement procedure in patients suffering from Graves orbitopathy. METHODS: In postprocessed 70 clinical CTs from adults of white European ethnicity with unaffected orbits, the authors assessed the intra- and interindividual variability of the orbital rim angulation and orbital rim position relative to their medial rim parts. This included morphometrical analysis and computer model visualization using Amira software (version 5.3.1, Visage Imaging GmbH, Berlin, Germany). RESULTS: Significant variation was observed in rim angulation, varying up to 16.6° in different individuals. A large variability of the sagittal rim position became evident, with the highest at the lateral orbital rim being 1.1 cm. CONCLUSIONS: These anatomical data may be used to benchmark the given Graves orbitopathy patients. CT assessment to detect and quantify orbital rim pro-/retrusion may help to decide whether orbital rim advancement may be considered for orbital decompression/enlargement.

Cup positioning in total hip arthoplasty: spatial alignment of the acetabular entry plane.

PURPOSE: Correct cup positioning is one of the keys for successful total hip replacement. There are mechanical and computer assistant guides for correct cup positioning in the market. To optimize the cup positioning, the use of navigation systems is recommended. The aim of this study was to compare spatial orientation of the acetabulary entry plane in relation to tables plane which is used by mechanical guides as well as anterior pelvic plane used for cup orientation by navigation systems. METHODS: CT raw data of 80 Caucasians (160 acetabuli) (done in supine position) with osteoartritic hips were collected. 3-D pelvic reconstruction was generated using Amira software (Visage Imaging Berlin, Germany). Anterior pelvic plane and acetabulary entry plane were defined by reliable anatomical landmarks. Spatial orientation were calculated by a custom made program code for the Amira software. RESULTS: There were no differences between anterior pelvic plane and table's plane as well as spatial orientation of acetabulary entry plane of both acetabuli in relation to anterior pelvic plane or table's plane. Furthermore, there was no correlation between age, sex or body mass index and spatial orientation of the acetabulary entry plane as well. CONCLUSIONS: The use of mechanical alignment guides for cup orientation during total hip arthroplasty based on table's plane in patient's supine position is a successful method to achieve proper cup orientation.

Typical accuracy and quality control of a process for creating CT-based virtual bone models.

A pragmatic method for assessing the accuracy and precision of a given processing pipeline required for converting computed tomography (CT) image data of bones into representative three dimensional (3D) models of bone shapes is proposed. The method is based on coprocessing a control object with known geometry which enables the assessment of the quality of resulting 3D models. At three stages of the conversion process, distance measurements were obtained and statistically evaluated. For this study, 31 CT datasets were processed. The final 3D model of the control object contained an average deviation from reference values of -1.07 ± 0.52 mm standard deviation (SD) for edge distances and -0.647 ± 0.43 mm SD for parallel side distances of the control object. Coprocessing a reference object enables the assessment of the accuracy and precision of a given processing pipeline for creating CT-based 3D bone models and is suitable for detecting most systematic or human errors when processing a CT-scan. Typical errors have about the same size as the scan resolution.

A method for computing general sacroiliac screw corridors based on CT scans of the pelvis.

Sacroiliac (SI) joint dislocations and sacral fractures of the pelvis can be stabilized by SI screws; however, screw insertion into a sacral isthmus region is risky for the adjacent neurovascular structures. Therefore, shape analyses of general SI screw corridors or safety zones are of great surgical interest; however, before such analyses can be conducted, a method for computing 3D models of general SI corridors from routine clinical computed tomography (CT) scans has to be developed. This work describes a method for determining general corridors in pelvic CT data for accurate screw placement into the first sacral body. The method is implemented with the computer language C++. The pelvic CT data are preprocessed before the presented algorithm computes a model of the 3D corridor volume. Additionally, the two most important parameters of the algorithm, the raster step and the virtual SI screw diameter, have been characterized. The result of the work is an algorithm for computing general SI screw corridors and its implementation. Additionally the influences of two important parameters, the raster step and the SI screw diameter, on corridor volume precision and computation time have been quantified for the test sample. We conclude that the method can be used in further corridor shape analyses with a large number of pelvic CT data sets for investigating general SI screw corridors and clinical consequences for the placements of the screws. Implementation of the presented software algorithm could also enhance performance of computer-assisted surgery in the near future.

3D computational anatomy of the scaphoid and its waist for use in fracture treatment.

BACKGROUND: A detailed understanding of scaphoid anatomy helps anatomic fracture reduction, and optimal screw position. Therefore, we analysed (1) the size and shape variations of the cartilage and osseous surface, (2) the distribution of volumetric bone mineral density (vBMD) and (3) if the vBMD values differ between a peripheral and a central screw pathway? METHODS: Forty-three fresh frozen hand specimens (17 females, 26 males) were analysed with high-resolution peripheral quantitative computed tomography (HR-pQCT) and dissected to compute a 3D-statistical osseous and cartilage surface model and a 3D-averaged vBMD model of the scaphoid. 3D patterns were analysed using principal component analysis (PCA). vBMD was analysed via averaging HR-pQCT grey values and virtual bone probing along a central and peripheral pathway. RESULTS: (1) PCA displayed most notable variation in length ranging from 1.7 cm (- 2SD) to 2.6 cm (mean) and 3.7 cm (+ 2SD) associated with differences of the width and configuration of the dorsal surface (curved and narrow (4 mm) to a wider width (9 mm)). (2) High vBMD was located in the peripheral zone. Lowest vBMD was observed in the centre and waist. (3) Virtual probing along a peripheral pathway near to the cartilage surfaces for the capitate and lunate allowed the center region to be bypassed, resulting in increased vBMD compared to a central pathway. CONCLUSION: High anatomical variations regarding the osseous and cartilage surfaces were associated with three distinct concentrically arranged zones with notable different vBMD. The complex scaphoid anatomy with its waist might alter the strategy of fracture fixation, education and research.

Artificial intelligence and CT-based 3D statistical modeling to assess transsacral corridors and plan implant positioning.

Transsacral corridors at levels S1 and S2 represent complex osseous spaces allowing percutaneous fixation of non- or minimally-displaced fragility fractures of the sacrum. To safely place transsacral implants, they must be completely intraosseous. However, standard radiographs and CT do not properly demonstrate the corridor's intricate configuration. Our goal was to facilitate the three-dimensional assessment of transsacral corridors using artificial intelligence and the planning of transsacral implant positioning. In total, 100 pelvic CTs (49 women, mean age: 58.6 ± SD 14.8 years; 51 men, mean age: 60.7 ± SD 13 years) were used to compute a 3D statistical model of the pelvic ring. On the basis of morphologic features (=predictors) and principal components scores (=response), regression learners were interactively trained, validated, and tuned to predict/sample personalized 3D pelvic models. They were matched via thin-plate spline transformation to a series of 20 pelvic CTs with fragility fractures of the sacrum (18 women and 2 men, age: 69-9.5 years, mean age: 78.65 ± SD 8.4 years). These models demonstrated the availability, dimension, cross-section, and symmetry of transsacral corridors S1 and S2, as well as the planned implant position, dimension, axes, and entry and exit points. The complete intraosseous pathway was controlled in CT reconstructions. We succeeded to establish a workflow determining transsacral corridors S1 and S2 using artificial intelligence and 3D statistical modeling.

Anatomical evaluation of the transpubic screw corridor based on a 3D statistical model of the pelvic ring.

Retrograde transpubic screw fixation is a common procedure for the treatment of anterior pelvic ring fractures. With its sparing surgical approach and significant pain relief after screw fixations allowing early mobilisation, it has gained importance especially in the treatment of insufficiency fractures in elderly patients. However, positioning of transpubic screw osteosynthesis is not always possible due to narrowness and curvature of the screw corridor. The aim of the present study was to evaluate availability and length of the screw corridor using a 3D statistical model of the pelvic ring consisting out of 150 uninjured pelves. Virtual bore probes with a diameter of 7.5 mm were analysed as to accessibility, length and grey value distribution in Hounsfield Unit (HU). A transpubic corridor with a diameter of ≥ 7.5 mm was available in 185 of 300 investigated superior pubic rami with mean screw length of 131.7 mm. Accessibility of the screw corridor was higher in males than in females. However, screw length showed no systematic differences between the sexes or ethnicities. Analysis of the grey value distribution demonstrated the strongest bone to be located at the lateral ilium and the supraacetabular region.

Anatomy-based surgical concepts for individualized orbital decompression surgery in graves orbitopathy. I. Orbital size and geometry.

PURPOSE: To analyze orbital morphological parameters that potentially could influence the effect of decompression surgery on exophthalmos reduction in Graves orbitopathy, thus making decompression surgery more predictable. METHODS: To generate a reference database, a CT-based study was performed in 140 orbits obtained from adult patients with unaffected orbits in a European white ethnicity. The following parameters were chosen: orbital volume, globe volume, globe to orbital volume ratio, and orbital cone angle. Volumes were measured on postprocessed CT data using morphometric techniques. To define the cone angle, a 3-dimensional approach was chosen using the program Amira. RESULTS: Significant interindividual variation was found in orbital volume from 18.9 to 33.4 ml and in globe volume from 6.0 to 10.1 ml. The globe to orbital volume ratio showed a relatively broad variation from 0.25 to 0.4. Differences in the orbital cone angle from 39.7° to 65.7° were observed. CONCLUSION: The experienced large variations in orbital morphology might significantly influence the degree of exophthalmos reduction, which can be obtained by standardized decompression procedures. Based on our results, a prospective clinical study will be conducted to test our hypothesis.

A method for assessing 3D shape variations of fuzzy regions and its application on human bony orbits.

In complex orbital defects, typically the eye globe is retruded in a pathological position. This is associated with severe functional and cosmetic post-traumatic conditions. Characteristically, the posterior orbital floor and the medial wall of the bony orbit (=region of interest, ROI) is fractured where adequate reconstruction is crucial for a satisfactory surgical outcome but difficult to achieve. By introducing the concept of preshaped, navigated orbital implants, the repair of complex orbital fracture patterns could be significantly facilitated and improved. However, this ROI, delineated according to surgical criteria, cannot be defined by distinct anatomical landmarks because of the absence of reliable anatomical features. The determination of homologous surface points therefore remains a problem in such regions. The aim of this study was to provide a method for the assessment of the 3D shape of the ROI and of its variability, respectively. By aligning an anatomically determinable region that embeds the region of interest with a thin plate spline, transformation homology can be determined suitable for subsequent state-of-the-art shape analysis. First results of shape variations are illustrated and give hints into the future of optimized implant design.

Development of generic Asian pelvic bone models using CT-based 3D statistical modelling.

BACKGROUND/OBJECTIVE: Artificial bone models (ABMs) are used in orthopaedics for research of biomechanics, development of implants and educational purposes. Most of the commercially available ABMs approximate the morphology of Europeans, but they may not depict the Asian anatomy. Therefore, our aim was to develop the first Asian ABM of the pelvis and compare it with the existing pelvic ABM (Synbone®; Caucasian male). METHODS: One hundred clinical computed tomography (CTs) of adult pelvises (male n â€‹= â€‹50, female n â€‹= â€‹50) of Malay, Chinese and Indian descent were acquired. CTs were segmented and defined landmarks were placed. Three 3D statistical pelvic model and mean models (overall, male, female) were generated. Anatomical variations were analysed using principal component analysis. To measure gender-related differences and differences to the existing ABM, distances between the anterior superior iliac spines (ASIS), the anterior inferior iliac spines (AIIS), the promontory and the symphysis (conjugate vera, CV) as well as the ischial spines (diameter transversa, DT) were quantified. RESULTS: Principal component analysis displayed large variability regarding the pelvic shape and size. Female and male statistical models were similar in ASIS (225 â€‹± â€‹20; 227 â€‹± â€‹13 â€‹mm; P â€‹= â€‹0.4153) and AIIS (185 â€‹± â€‹11; 187 â€‹± â€‹10 â€‹mm; P â€‹= â€‹0.3982) and differed in CV (116 â€‹± â€‹10; 105 â€‹± â€‹10 â€‹mm; P â€‹< â€‹0.0001) and DT (105 â€‹± â€‹7; 88 â€‹± â€‹8 â€‹mm; P â€‹< â€‹0.0001). Comparing the unisex mean model with the pre-existing ABM, the ASIS (226; 275 â€‹mm; P â€‹< â€‹0.0001), the AIIS (186; 209 â€‹mm; P â€‹< â€‹0.0001) and the CV (111; 105 â€‹mm; P â€‹< â€‹0.0001) differed significantly. Both models were similar regarding DT (97; 95 â€‹mm; P â€‹= â€‹0.6927). The analysis revealed notable gender- and size-dependent anatomical variations within the Asian population. Chinese, Malay and Indian descents did not differ notably. The overall Asian model was smaller than the existing ABM. THE TRANSLATION POTENTIAL OF THIS ARTICLE: Owing to the large differences between the Asian ABM and the pre-existing ABM, as well as differences between genders, the use of an Asian- and gender-specific ABM is important to consider in research, biomechanics and implant development for this population.

Fit assessment of anatomic plates for the distal medial tibia.

OBJECTIVES: With the development and popularization of minimally invasive surgical methods and implants for fracture fixation, it is increasingly important that the available implants are precontoured to the specific anatomic location for which they are designed. The objective of this study was to develop a noninvasive method and criteria for quantifying the fit of a distal periarticular medial tibia plate and to test the method on a small set of tibia models. METHODS: The undersurface of the plate was extracted from a digital model of the plate. The surface of the plate was fitted to 21 computer tomography (CT)-based 3-dimensional (3-D) models of human tibiae. Four criteria were defined that constitute an anatomic plate fit and subsequently were applied for the quantitative fit assessment. The fitting of the plate undersurface to the bone was entirely conducted in a virtual environment. RESULTS: An anatomic fit of the plate was achieved for 4 of the models (19%). The individual categories generated fits of 62% (n = 13) for the proximal end; 43% (n = 9) for the proximal angle; 57% (n = 12) for the middle distance; and 57% (n = 12) for a distal fit. CONCLUSIONS: Although for the 4 individual criteria plate fits of 43%-62% were achieved, a global/anatomic fit only occurred for 19% of the bone models. This outcome is likely a result of bone morphology variations, which exist in a random population sample combined with the effects of a nonoptimized plate shape. Recommendations for optimizing the fit of the plate are discussed.

Secure corridor for infraacetabular screws in acetabular fracture fixation-a 3-D radiomorphometric analysis of 124 pelvic CT datasets.

BACKGROUND: Acetabular fracture surgery is directed toward anatomical reduction and stable fixation to allow for the early functional rehabilitation of an injured hip joint. Recent biomechanical investigations have shown the superiority of using an additional screw in the infraacetabular (IA) region, thereby transfixing the separated columns to strengthen the construct by closing the periacetabular fixation frame. However, the inter-individual existence and variance concerning secure IA screw corridors are poorly understood. METHODS: This computer-aided 3-D radiomorphometric study examined 124 CT Digital Imaging and Communications in Medicine (DICOM) datasets of intact human pelves (248 acetabula) to visualize the spatial IA corridors as the sum of all intraosseous screw positions. DICOM files were pre-processed using the Amira® 4.2 visualization software. Final corridor computation was accomplished using a custom-made software algorithm. The volumetric measurement data of each corridor were calculated for further statistical analyses. Correlations between the volumetric values and the biometric data were investigated. Furthermore, the influence of hip dysplasia on the IA corridor configuration was analyzed. RESULTS: The IA corridors consistently showed a double-cone shape with the isthmus located at the acetabular fovea. In 97% of male and 91% of female acetabula, a corridor for a 3.5-mm screw could be found. The number of IA corridors was significantly lower in females for screw diameters ≥ 4.5 mm. The mean 3.5-mm screw corridor volume was 16 cm3 in males and 9.2 cm3 in female pelves. Corridor volumes were significantly positively correlated with body height and weight and with the diameter of Köhler's teardrop on standard AP pelvic X-rays. No correlation was observed between hip dysplasia and the IA corridor extent. CONCLUSION: IA corridors are consistently smaller in females. However, 3.5-mm small fragment screws may still be used as the standard implant because sex-specific differences are significant only with screw diameters ≥ 4.5 mm. Congenital hip dysplasia does not affect secure IA screw insertion. The described method allows 3-D shape analyses with highly reliable results. The visualization of secure IA corridors may support the spatial awareness of surgeons. Volumetric data allow the reliable assessment of individual IA corridors using standard AP X-ray views, which aids preoperative planning.