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1.
Treatment with a VEGFR-2 antibody results in intra-tumor immune modulation and enhances anti-tumor efficacy of PD-L1 blockade in syngeneic murine tumor models.
PLoS One
; 17(7): e0268244, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35849586
2.
Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.
Front Pharmacol
; 13: 829063, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35795558
3.
SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery.
J Immunother Cancer
; 8(2)2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33268350
4.
Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity.
Mol Cancer Ther
; 19(4): 988-998, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32241872
5.
Immunomodulatory Activity of a Colony-stimulating Factor-1 Receptor Inhibitor in Patients with Advanced Refractory Breast or Prostate Cancer: A Phase I Study.
Clin Cancer Res
; 26(21): 5609-5620, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32847933
6.
Bispecific Targeting of PD-1 and PD-L1 Enhances T-cell Activation and Antitumor Immunity.
Cancer Immunol Res
; 8(10): 1300-1310, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32873605
7.
Randomised phase II study of second-line olaratumab with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer.
Eur J Cancer
; 107: 186-195, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30573277
8.
Genomic characterization of intrinsic and acquired resistance to cetuximab in colorectal cancer patients.
Sci Rep
; 9(1): 15365, 2019 10 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31653970
9.
The Folate Pathway Inhibitor Pemetrexed Pleiotropically Enhances Effects of Cancer Immunotherapy.
Clin Cancer Res
; 25(23): 7175-7188, 2019 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31409612
10.
Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance.
Mol Cancer Ther
; 17(2): 521-531, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29158469
11.
Targeting the TGFß pathway with galunisertib, a TGFßRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockade.
J Immunother Cancer
; 6(1): 47, 2018 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29866156
12.
Correction to: Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054.
J Immunother Cancer
; 6(1): 45, 2018 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29866166
13.
Discovery and preclinical characterization of the antagonist anti-PD-L1 monoclonal antibody LY3300054.
J Immunother Cancer
; 6(1): 31, 2018 04 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-29712568
14.
The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade.
Cell Rep
; 22(11): 2978-2994, 2018 03 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-29539425
15.
An Open-Label, Multicenter, Randomized, Phase II Study of Cisplatin and Pemetrexed With or Without Cixutumumab (IMC-A12) as a First-Line Therapy in Patients With Advanced Nonsquamous Non-Small Cell Lung Cancer.
J Thorac Oncol
; 12(2): 383-389, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27464970
16.
Mouse PDX Trial Suggests Synergy of Concurrent Inhibition of RAF and EGFR in Colorectal Cancer with BRAF or KRAS Mutations.
Clin Cancer Res
; 23(18): 5547-5560, 2017 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28611205
17.
High-content molecular profiling of T-cell therapy in oncology.
Mol Ther Oncolytics
; 3: 16009, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27626060
18.
Clinical and Translational Results of a Phase II, Randomized Trial of an Anti-IGF-1R (Cixutumumab) in Women with Breast Cancer That Progressed on Endocrine Therapy.
Clin Cancer Res
; 22(2): 301-9, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26324738
19.
Intrinsic Resistance to Cixutumumab Is Conferred by Distinct Isoforms of the Insulin Receptor.
Mol Cancer Res
; 13(12): 1615-26, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26263910
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