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1.
Ann Vasc Surg ; 2024 Jun 27.
Artículo en Inglés | MEDLINE | ID: mdl-38944192

RESUMEN

Thoracic aortic aneurysms evolving within a type IIIb chronic aortic dissection are mostly treated with the deployment of an endograft. However, several cases of dissecting aneurysms are associated with a significant dilatation of the aortic arch. These cases are usually managed in two steps : arch reconstruction or supra-aortic trunk debranching at first and a secondary graft deployment for the descending thoracic aorta. We present through this case series an alternative approach for this severe condition which consists in the replacement of the thoracic aorta from its hemi-arch to the distal thoracic or visceral aorta using a left thoracotomy. We deliberately neglected the remaining dissecting aorta if its diameter was below 45 mm, hypothesizing its non evolution after repair. From 2012 to 2021, 9 patients have been treated for a thoracic aneurysm evolving after a IIIb chronic aortic dissection using a left thoracotomy and a 19°C circulatory arrest. Immediate postoperative results show no mortality nor neurological disorders and the 7 years follow up for all of these 9 cases enlightened the absence of aneurysmal evolution especially for the distal anastomosis and the remaining dissected aorta. This work suggests that this direct approach strategy can definitively treat a thoracic dissecting aneurysm unsuitable for a simple endovascular treatment.

2.
Ann Vasc Surg ; 105: 125-131, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38588952

RESUMEN

BACKGROUND: Endovascular aortic surgery is increasingly becoming the standard treatment. Percutaneous access preclosing systems appear to be effective and notably the Proglide (PG). We aimed to prospectively assess the clinical effectiveness of combining ultrasound-guided femoral puncture with ultrasound-guided PG deployment. METHODS: Our single-center study consecutively included patients managed at a tertiary center from May to September 2023, undergoing endovascular aortic surgery. The placement of PG was performed under ultrasound guidance. Preoperative patient characteristics were evaluated using preoperative computed tomography scans. Clinical and technical success were defined, respectively, as the ability to achieve complete hemostasis confirmed by ultrasound 48 hr postprocedure and as the successful placement of a PG under ultrasound guidance contributing to final hemostasis. RESULTS: Twenty patients were included over a 6-month period, totaling 34 common femoral arteries (CFAs). Fourteen were male, with an average age of 72.8 ± 8.2 years. Among the 34 CFA, CFA had diameter of 12.05 ± 2.4 mm and a depth of 38.0 ± 13.4 mm. The mean introducer sheath diameter was 6.2 ± 1.5 mm with a sheath to femoral artery ratio of 0.54 ± 0.18. Successful Proglide placement under ultrasound guidance was achieved in 100% of cases. No PG failure occurred. Clinical and technical success were, respectively, of 95% and 100%. One small pseudoaneurysm was observed at 48 hr treated medically. No CFA access reintervention was required. CONCLUSIONS: The technique of ultrasound-guided PG deployment in aortic surgery is a safe and effective method for achieving hemostasis. It effectively prevents PG failures at a lower cost.


Asunto(s)
Procedimientos Endovasculares , Arteria Femoral , Técnicas Hemostáticas , Punciones , Ultrasonografía Intervencional , Humanos , Masculino , Procedimientos Endovasculares/efectos adversos , Procedimientos Endovasculares/instrumentación , Femenino , Anciano , Arteria Femoral/diagnóstico por imagen , Arteria Femoral/cirugía , Resultado del Tratamiento , Estudios Prospectivos , Técnicas Hemostáticas/instrumentación , Técnicas Hemostáticas/efectos adversos , Anciano de 80 o más Años , Persona de Mediana Edad , Cateterismo Periférico/efectos adversos , Dispositivos de Cierre Vascular , Hemostáticos/administración & dosificación , Hemostáticos/uso terapéutico , Factores de Tiempo
3.
Ann Vasc Surg ; 93: 18-28, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36572096

RESUMEN

BACKGROUND: We hypothesized that supraceliac aortic cross clamping could induce lung injury mediated by an inflammatory ischemia-reperfusion (IR) trigger. We aimed to characterize glycocalyx (GCX), a component of endothelial membrane, participating to remote lung injury. METHODS: Rats underwent supraceliac aortic cross clamping for 40 min and were sacrificed at 0, 3, 6, and 24 hr of reperfusion (n = 10/group). Each group was compared to sham (n = 6/group). GCX products (syndecan-1 [Sdc-1] and heparan sulfate [HS]), tumor necrosis factor-alpha (TNF-α), and interleukin-1ß (IL-1ß) were measured in plasma (enzyme-linked immunosorbent assay[ELISA]). Lungs were harvested for measurements of TNF-α, IL-1ß (polymerase chain reaction) and Sdc-1 (western blotting [WB]). Histologic lung injury scoring and pulmonary gravimetry were analyzed in a blinded manner. RESULTS: Plasmatic Sdc-1, HS, TNF-α, and IL-1ß reached peak levels at 3 hr. Levels were significantly higher in clamping groups than sham at 6 hr for Sdc-1, at 0 and 3 hr for HS, at 3 and 6 hr for TNF-α, and at 3 hr for IL-1ß. Lung TNF-α and Interleukin-1ß reached peak levels at 6 hr. Levels were significantly higher than sham at 6 and 24 hr for TNF-α and at 6 hr for IL-1ß. Lung Sdc-1 was lowest at 3 hr. Sdc-1 was not significantly different compared to sham at the different reperfusion times. At 3 hr, it was 0.27 ± 0.03 vs. 0.33 ± 0.02 (sham) (P = 0.09). Histopathologic scores at 6 and 24 hr were higher in clamping groups than sham. At 6 and 24 hr, it was higher for hemorrhage, polynuclear neutrophil (PNN) infiltration and intravascular leukocytes. Pulmonary edema was higher by gravimetry at 0 and 6 hr. CONCLUSIONS: Supra celiac aortic clamping causes early lung injury in relation with a systemic inflammatory response associated with altered GCX structure.


Asunto(s)
Lesión Pulmonar , Daño por Reperfusión , Ratas , Animales , Lesión Pulmonar/etiología , Interleucina-1beta , Factor de Necrosis Tumoral alfa , Constricción , Glicocálix , Resultado del Tratamiento , Pulmón/patología , Daño por Reperfusión/patología
4.
Ann Vasc Surg ; 71: 536.e5-536.e8, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33157251

RESUMEN

We present an uncommon case of a 16-year-old woman with type 1 neurofibromatosis and renovascular hypertension due to bilateral renal stenosis associated with asymptomatic digestive artery stenosis. Our patient was treated by several autologous bypasses to the superior mesenteric artery and the left and right renal arteries. She had no postoperative complications and good clinical and imaging outcomes at 10 years. Furthermore, there are few data on the vascular impairment of this rare disease, thus justifying its presentation.


Asunto(s)
Arteria Femoral/trasplante , Hipertensión Renovascular/cirugía , Neurofibromatosis 1/complicaciones , Obstrucción de la Arteria Renal/cirugía , Injerto Vascular , Adolescente , Antihipertensivos/uso terapéutico , Femenino , Humanos , Hipertensión Renovascular/diagnóstico por imagen , Hipertensión Renovascular/etiología , Neurofibromatosis 1/diagnóstico , Obstrucción de la Arteria Renal/diagnóstico por imagen , Obstrucción de la Arteria Renal/etiología , Trasplante Autólogo , Resultado del Tratamiento
5.
Ann Vasc Surg ; 69: 449.e7-449.e9, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32502680

RESUMEN

We present a case of abdominal aortic aneurysm open repair planned with temporary left ventricular support (Impella®) in a patient suffering from severe chronic heart failure. Only 1 single similar case was reported in the literature from 1974.


Asunto(s)
Aneurisma de la Aorta Abdominal/cirugía , Insuficiencia Cardíaca/terapia , Corazón Auxiliar , Hemodinámica , Procedimientos Quirúrgicos Vasculares , Función Ventricular Izquierda , Anciano , Aneurisma de la Aorta Abdominal/diagnóstico por imagen , Aneurisma de la Aorta Abdominal/fisiopatología , Enfermedad Crónica , Insuficiencia Cardíaca/diagnóstico , Insuficiencia Cardíaca/fisiopatología , Humanos , Masculino , Resultado del Tratamiento
6.
Ann Vasc Surg ; 68: 316-325, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-32439519

RESUMEN

BACKGROUND: Type IV thoracoabdominal aortic aneurysm surgical repair is often complicated by postoperative acute kidney injury. The aim was to evaluate early renal injury influence on long-term renal function. METHODS: All type IV thoracoabdominal surgical repair performed between January 2000 and January 2014 in our tertiary hospital were included in this retrospective observational study. All procedures were performed through a retroperitoneal approach with at least suprarenal aortic cross-clamping. Cold Ringer Lactate was used to perfuse the kidneys. Serum creatinine (Scr.) and glomerular filtration rate (GFR) were recorded preoperatively, daily until discharge and at least annually during follow-up. Postoperative renal dysfunction was classified using the RIFLE score. Predictors of long-term renal decline were identified by logistic regression and a Cox model. RESULTS: Of total, 80 patients were included. Aortic clamping level was suprarenal (10%), supramesenteric (37%) or supracoeliac (53%). Ischemic durations were 29 ± 9 min for the gastrointestinal tract and the right kidney, 54 ± 28 min for the left kidney. Three patients died postoperatively. At discharge, 31 (38.8%) patients did not have a postoperative renal impairment (RIFLE-), compared with 49 (61.2%) who had a renal dysfunction (RIFLE+). GFR was 89 ± 29 ml/min vs 68 ± 37 ml/min, respectively (P < 0.01). In the RIFLE + group, Scr. was increased by x1.5 (Risk) for 22 patients, x2 (Injury) for 19 patients, and ×3 (Failure) for 8 patients. Mean follow-up was 59 months. Eighteen patients died, and 2 patients started permanent dialysis at 46 and 118 months during follow-up. The only predictive factor of long-term GFR degradation was a postoperative GFR below 45 ml/min (OR: 16.5; 95%; P < 0.001). CONCLUSIONS: Postoperative renal dysfunction was a frequent complication, associated with long-term renal function degradation.


Asunto(s)
Lesión Renal Aguda/etiología , Aneurisma de la Aorta Abdominal/cirugía , Implantación de Prótesis Vascular/efectos adversos , Tasa de Filtración Glomerular , Riñón/fisiopatología , Lesión Renal Aguda/diagnóstico , Lesión Renal Aguda/fisiopatología , Anciano , Aneurisma de la Aorta Abdominal/diagnóstico por imagen , Biomarcadores/sangre , Creatinina/sangre , Progresión de la Enfermedad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Medición de Riesgo , Factores de Riesgo , Factores de Tiempo , Resultado del Tratamiento
7.
BMC Surg ; 20(1): 193, 2020 Aug 27.
Artículo en Inglés | MEDLINE | ID: mdl-32854681

RESUMEN

BACKGROUND: Open surgical repair (OSR) for thoracoabdominal aortic aneurysms (TAA) is associated with a high pulmonary and renal morbidity rate. Ischemic preconditioning (IPC) is a mechanism of protection against the deleterious effects of ischemia-reperfusion. To our knowledge IPC has never been tested during OSR for TAA. METHODS: The primary objective of the study is to evaluate the efficacy of IPC during OSR for TAA with respect to acute kidney injury (AKI) according to KDIGO and pneumonia/prolonged ventilation-time during the first 8 postoperative days. The secondary objectives are to compare both arms with respect to cardiac complications within 48 h, renal and pulmonary complications within 21 days and mortality at 60 days. To assess the efficacy of IPC with respect to pulmonary and renal morbidity, a cox model for competing risks will be used. Assuming that the event occurs among 36% of the patients when no IPC is performed, the allocation of 55 patients to each arm should allow detecting a hazard ratio of at least 2.75 with a power of 80% when admitting 5% for an error of first kind. This means that 110 patients, enrolled in this multicenter study, may be randomised within 36 months of the first randomization. Randomization will be performed to allocate patients either to surgery with preconditioning before aortic cross clamping (Arm 1) or to surgery without preconditioning before aortic cross clamping (Arm 2). Randomization takes place during the intervention after intravenous injection of heparin, or after the start of femoral assistance. The procedure for IPC will be a supra-visceral thoracic aortic cross clamping for 5 min followed by an unclamping period of 5 min. This procedure will be repeated twice before starting thoracic aortic cross clamping needed to perform surgery. CONCLUSIONS: Our hypothesis is that ischemic preconditioning could reduce clinical morbidity and the incidence of lung damage associated with supra-visceral aortic clamping. TRIAL REGISTRATION: EPICATAStudy registered in ClinicalTrial.gov / number: NCT03718312 on Oct.24.2018 URL number.


Asunto(s)
Aneurisma de la Aorta Torácica , Precondicionamiento Isquémico , Daño por Reperfusión/prevención & control , Lesión Renal Aguda/etiología , Lesión Renal Aguda/prevención & control , Aorta/cirugía , Aneurisma de la Aorta Torácica/complicaciones , Aneurisma de la Aorta Torácica/cirugía , Implantación de Prótesis Vascular , Puente Cardiopulmonar , Constricción , Cardiopatías/etiología , Cardiopatías/prevención & control , Humanos , Hipotermia Inducida , Isquemia/etiología , Isquemia/prevención & control , Precondicionamiento Isquémico/métodos , Enfermedades Pulmonares/etiología , Enfermedades Pulmonares/prevención & control , Morbilidad , Ensayos Clínicos Controlados Aleatorios como Asunto , Daño por Reperfusión/etiología , Resultado del Tratamiento
8.
Ann Vasc Surg ; 58: 378.e1-378.e3, 2019 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-30763713

RESUMEN

Totally occluded aortic aneurysm is a rare pathology. The medical history and the evolution are unknown. We present a case of a regularly followed up 60-year-old man with chronic thrombosed aneurysm, presenting with mycotic acute rupture. As an original treatment, the patient was treated by aortic ligation without distal revascularization. A literature review from 1974 to 2015 enhances the contemporary understanding of the pathology, by exploring the thrombus interaction, pressure, and the wall shear stress. The literature review confirms the poor prognosis and concludes of a necessary closer follow-up for chronic occluded aneurysm.


Asunto(s)
Aneurisma Infectado/complicaciones , Aneurisma de la Aorta Abdominal/complicaciones , Rotura de la Aorta/etiología , Trombosis/etiología , Aneurisma Infectado/diagnóstico por imagen , Aneurisma Infectado/fisiopatología , Aneurisma Infectado/cirugía , Aneurisma de la Aorta Abdominal/diagnóstico por imagen , Aneurisma de la Aorta Abdominal/fisiopatología , Aneurisma de la Aorta Abdominal/cirugía , Rotura de la Aorta/diagnóstico por imagen , Rotura de la Aorta/fisiopatología , Rotura de la Aorta/cirugía , Aortografía/métodos , Enfermedad Crónica , Angiografía por Tomografía Computarizada , Hemodinámica , Humanos , Síndrome de Leriche/etiología , Ligadura , Masculino , Persona de Mediana Edad , Flujo Sanguíneo Regional , Trombosis/diagnóstico por imagen , Trombosis/fisiopatología , Trombosis/cirugía , Resultado del Tratamiento
9.
Ann Vasc Surg ; 54: 261-268, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-30092435

RESUMEN

The occurrence of transplant renal artery stenosis (TRAS) ranges from 1 to 23% and is associated with resistant hypertension, volume overload, graft dysfunction, and poor long-term graft and patient survival. Enhancing graft availability with expanded criteria donors results in the transplantation of kidneys with atherosclerotic arteries, increasing the risk of vascular complications. Although endovascular management is the first-line strategy in this context, in some patients, surgery has to be considered. We report the experience and long-term follow-up of TRAS surgery in a French kidney transplantation center. Between 2004 and 2009, 10 patients with postoperative TRAS, considered unfit for an endovascular procedure by a multidisciplinary team, were addressed for surgery. Mean time from transplantation to surgery was 139.8 ± 136.4 days. Clinical indications were oliguria, anuria, or acute decrease in urine output (n = 5), resistant hypertension (n = 4), and persistence of a decreased allograft function (n = 1). Imaging-revealed ostial stenosis is associated with external iliac artery stenosis (n = 3) or early bifurcation (n = 2), and kinking (n = 5). Revascularization techniques consisted in a great saphenous vein bypass (n = 5) and internal iliac artery anastomosis (n = 5). In the postoperative period, there was no graft loss, but 2 patients required hemodialysis during the first week. Mean follow-up was 9.8 ± 2.1 years. One patient lost his graft 10.3 years after transplantation due to chronic rejection, and 1 patient needed endovascular dilation. There was no graft loss at 5 years. Blood pressure was controlled in all patients. Surgical intervention for TRAS is safe and effective on graft survival and graft function and has to be considered for patients unsuitable for endovascular repair.


Asunto(s)
Trasplante de Riñón , Obstrucción de la Arteria Renal/cirugía , Adulto , Anastomosis Quirúrgica , Angiografía , Femenino , Estudios de Seguimiento , Supervivencia de Injerto , Humanos , Arteria Ilíaca/cirugía , Masculino , Persona de Mediana Edad , Obstrucción de la Arteria Renal/diagnóstico por imagen , Obstrucción de la Arteria Renal/etiología , Estudios Retrospectivos , Vena Safena/cirugía , Resultado del Tratamiento
10.
Eur J Nucl Med Mol Imaging ; 45(4): 549-557, 2018 04.
Artículo en Inglés | MEDLINE | ID: mdl-29159573

RESUMEN

PURPOSE: The growth phases of medically treated abdominal aortic aneurysms (AAA) are frequently associated with an 18F-fluorodesoxyglucose positron emission tomography (FDG-PET) pattern involving low baseline and subsequent higher FDG uptake. However, the FDG-PET patterns associated with the endovascular aneurysm repair (EVAR) of larger AAA are presently unknown. This study aimed to investigate the relationship between serial AAA FDG uptake measurements, obtained before EVAR and 1 and 6 months post-intervention and subsequent sac shrinkage at 6 months, a well-recognized indicator of successful repair. METHODS: Thirty-three AAA patients referred for EVAR (maximal diameter: 55.4 ± 6.0 mm, total volume: 205.7 ± 63.0 mL) underwent FDG-PET/computed tomography (CT) before EVAR and at 1 and 6 months thereafter, with the monitoring of AAA volume and of a maximal standardized FDG uptake [SUVmax] averaged between the axial slices encompassing the AAA. RESULTS: Sac shrinkage was highly variable and could be stratified into three terciles: a first tercile in which shrinkage was absent or very limited (0-29 mL) and a third tercile with pronounced shrinkage (56-165 mL). SUVmax values were relatively low at baseline in the 1st tercile (SUVmax: 1.69 ± 0.33), but markedly increased at 6 months (2.42 ± 0.69, p = 0.02 vs. baseline). These SUV max values were by contrast much higher at baseline in the 3rd tercile (SUVmax: 2.53 ± 0.83 p = 0.009 vs. 1st tercile) and stable at 6 months (2.49 ± 0.80), while intermediate results were documented in the 2nd tercile. Lastly, the amount of sac shrinkage, expressed in absolute values or in percentages of baseline AAA volumes, was positively correlated with baseline SUVmax (p = 0.001 for both). CONCLUSION: A low pre-EVAR FDG uptake and increased AAA FDG uptake at 6 months are associated with reduced sac shrinkage. This sequential FDG-PET pattern is similar to that already shown to accompany growth phases of medically treated AAA.


Asunto(s)
Aneurisma de la Aorta Abdominal/diagnóstico por imagen , Procedimientos Endovasculares , Tomografía de Emisión de Positrones , Aorta , Aneurisma de la Aorta Abdominal/cirugía , Fluorodesoxiglucosa F18 , Humanos , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
12.
Ann Vasc Surg ; 52: 192-200, 2018 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-29673584

RESUMEN

BACKGROUND: The treatment of thoracoabdominal aortic aneurysms through an open approach has general and pulmonary consequences of multiple etiologies. Our assumption was that the supraceliac aortic clamping needed for this operation causes a systemic inflammatory response associated with a pulmonary attack. METHODS: We developed a model of 30-min supraceliac aortic clamping in Wistar rats weighing 300 g. After 90 min of reperfusion, the rats were sacrificed. The effects on the digestive tract wall were analyzed by measurement of the mucosal thickness/total thickness ratio. The effects on the mesenteric endothelial function were determined by an ex situ measurement of the arterial pressure/volume curves (third branch). The systemic consequences of the procedure were analyzed by dosing tumor necrosis factor alpha (TNFα), interleukin (IL)1ß, and IL10 in the blood. The pulmonary consequences were analyzed by the measurement of macrophages, polymorphonuclear neutrophils (PNs), T lymphocyte infiltration, pulmonary apoptosis (TUNEL) and active caspase 3. The experimental scheme included 20 rats with ischemia-reperfusion (IR) and 20 control rats. An analysis of survival was carried out on 20 other rats (10 IR and 10 controls). RESULTS: The results were expressed as average ± standard error of the mean. The statistical tests were Student's t-test and Mann-Whitney test. This visceral IR model decreased the ratio of the thickness of the intestinal mucosa compared with that of the control rats (0.77 ± 0.008 vs. 0.82 ± 0.009 [P < 0.001]). This local effect was not accompanied by any mesenteric endothelial dysfunction (P = 0.91). On a systemic level, IR increased TNFα (37.9 ± 1.5 vs. 28.2 ± 0.6 pg/mL; P < 0.0001), IL1ß (67.1 ± 9.8 vs. 22.5 ± 5.6 pg/mL; P < 0.001), and IL10 (753.3 ± 96 vs. 3.7 ± 1.7 pg/mL; P < 0.0001). As regards the lungs, IR increased the parenchymal cellular infiltration by macrophages (6.8 ± 0.8 vs. 4.5 ± 0.4 cells per field; P < 0.05) and PNs (7.4 ± 0.5 vs. 6.2 ± 03 cells per field; P < 0.05). There was no increase in the pulmonary cellular apoptosis measured by TUNEL (P = 0.77) or in the caspase 3 activity (P = 0.59). The mortality of the visceral IR rats was 100% at 36 hr vs. 0% in the animals without IR. CONCLUSIONS: This work showed that the inflammatory response to visceral IR had systemic and pulmonary effects which always results in the death in the rat.


Asunto(s)
Aorta/cirugía , Lesión Pulmonar/etiología , Daño por Reperfusión/etiología , Síndrome de Respuesta Inflamatoria Sistémica/etiología , Procedimientos Quirúrgicos Vasculares/efectos adversos , Animales , Aorta/fisiopatología , Apoptosis , Quimiotaxis de Leucocito , Constricción , Citocinas/sangre , Mediadores de Inflamación/sangre , Mucosa Intestinal/patología , Pulmón/metabolismo , Pulmón/patología , Lesión Pulmonar/sangre , Lesión Pulmonar/patología , Activación de Macrófagos , Macrófagos/metabolismo , Macrófagos/patología , Masculino , Ratas Wistar , Daño por Reperfusión/sangre , Daño por Reperfusión/patología , Síndrome de Respuesta Inflamatoria Sistémica/sangre , Síndrome de Respuesta Inflamatoria Sistémica/patología , Linfocitos T/metabolismo , Linfocitos T/patología , Factores de Tiempo
13.
J Vasc Surg ; 63(4): 902-8, 2016 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-26610645

RESUMEN

BACKGROUND: Persistent type II endoleaks (T2Ls) with sac enlargement after endovascular abdominal aortic aneurysm repair are still of concern in view of the potential for rupture. Current treatments (embolization and stent graft [SG] explantation) are associated with lack of efficacy or high perioperative morbidity and mortality. This study evaluated an alternative technique that combines sacotomy, ligation of patent back-bleeding vessels, and SG preservation for T2L or unspecified endoleak repair. METHODS: This multicenter study in France included 28 patients (27 men; median age, 78 years). Twenty-one patients (75%) had a bifurcated SG (including 3 fenestrated SGs) and seven (25%) had an aortouni-iliac SG (2 for ruptured aneurysm). Unsuccessful embolization had been performed in 10 patients (36%). Four patients (14%) presented sac enlargement with no endoleak visible on computed tomography. The origin of the endoleak remained unspecified in three patients 3 (11%). The median diameter of the aneurysmal sac was 78 mm (vs 55 mm at the time of endovascular abdominal aortic aneurysm repair) after a median follow-up of 24 months. RESULTS: A transperitoneal approach was used in 21 patients (75%) and a retroperitoneal approach was used in seven (25%). A guidewire was placed in the supraceliac aorta in 14 patients, and an occlusion balloon was temporarily inflated in six. Aortic cross-clamping was performed in five patients. T2Ls were identified in 26 patients, and associated with a distal type I endoleak in 1 patient, a type III endoleak in 3, and a type IV endoleak in 1. Two patients presented with endotension. All the endoleaks were treated successfully, with a mean operating time of 120 minutes and a mean blood loss of 450 mL. One SG was explanted 12 days after the procedure because of early infection. One patient died during SG explantation for an aortoduodenal fistula 26 months after the endoaneurysmorrhaphy. During a median follow-up of 24 months, the control computed tomography scan showed shrinkage of the aneurysmal sac with stable diameters in all patients. No missed T2Ls, no recurrence of T2L, and no SG migration or disjunction was observed. CONCLUSIONS: Obliterating endoaneurysmorrhaphy with SG preservation can be considered as an alternative to SG removal in cases of persistent T2L responsible for aneurysmal sac enlargement after embolization failure. By avoiding extensive dissection for surgical aortic cross-clamping, minimizing hemodynamic changes, and reducing blood loss and operating time, this procedure can be performed even in patients initially considered unfit for surgery.


Asunto(s)
Aneurisma de la Aorta Abdominal/cirugía , Implantación de Prótesis Vascular/efectos adversos , Endofuga/cirugía , Procedimientos Endovasculares/efectos adversos , Anciano , Anciano de 80 o más Años , Aneurisma de la Aorta Abdominal/diagnóstico , Aneurisma de la Aorta Abdominal/mortalidad , Aortografía/métodos , Oclusión con Balón , Pérdida de Sangre Quirúrgica , Prótesis Vascular/efectos adversos , Implantación de Prótesis Vascular/instrumentación , Implantación de Prótesis Vascular/mortalidad , Remoción de Dispositivos , Embolización Terapéutica , Endofuga/diagnóstico , Endofuga/etiología , Endofuga/mortalidad , Procedimientos Endovasculares/instrumentación , Procedimientos Endovasculares/mortalidad , Femenino , Francia , Humanos , Ligadura , Masculino , Persona de Mediana Edad , Tempo Operativo , Selección de Paciente , Diseño de Prótesis , Infecciones Relacionadas con Prótesis/diagnóstico , Infecciones Relacionadas con Prótesis/cirugía , Reoperación , Estudios Retrospectivos , Medición de Riesgo , Factores de Riesgo , Stents/efectos adversos , Factores de Tiempo , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
15.
Ann Vasc Surg ; 36: 127-131, 2016 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27427350

RESUMEN

BACKGROUND: Distal aortic retrograde perfusion systems like the left heart bypass or femoro-femoral extracorporeal circulation are the methods of reference for organ protection during direct approaches to thoracoabdominal aortic aneurysms. The aim of this work was to evaluate the use of a passive arterial shunt to reduce visceral ischemia during aortic operations when occlusive diseases of the iliac arteries make distal aortic retrograde perfusion inappropriate. METHODS: Ten patients affected by a Crawford type III thoracoabdominal aneurysm (TAA) were operated on between January 2013 and January 2015 with the use of a temporary shunt inserted onto the left axillar artery that allows visceral perfusion immediately after the aorta is opened. The operation was performed after a single dose of heparin (50 UI/kg). The sera lactate levels were measured 2 hr after the last aortic clamp was removed and compared with those obtained from a group of 19 patients operated on for a Crawford type IV TAA during the same period without any arterial shunt. RESULTS: Neither mortality nor paraplegia occurred. The sera lactate levels were lower in the group of patients operated on for a type III TAA (2.57 ± 1) than for a type IV TAA (3.68 ± 1) (P < 0.01, Student's t-test). CONCLUSION: This method was effective for low mesenteric ischemia, easy to perform, and did not require high doses of anticoagulants.


Asunto(s)
Aneurisma de la Aorta Torácica/cirugía , Arteria Axilar/cirugía , Implantación de Prótesis Vascular , Perfusión/métodos , Adulto , Anciano , Anticoagulantes/administración & dosificación , Aneurisma de la Aorta Torácica/diagnóstico por imagen , Aneurisma de la Aorta Torácica/fisiopatología , Arteria Axilar/diagnóstico por imagen , Arteria Axilar/fisiopatología , Biomarcadores/sangre , Implantación de Prótesis Vascular/efectos adversos , Heparina/administración & dosificación , Humanos , Ácido Láctico/sangre , Masculino , Isquemia Mesentérica/etiología , Isquemia Mesentérica/fisiopatología , Isquemia Mesentérica/prevención & control , Persona de Mediana Edad , Perfusión/efectos adversos , Flujo Sanguíneo Regional , Estudios Retrospectivos , Factores de Riesgo , Resultado del Tratamiento
16.
Ann Vasc Surg ; 36: 199-207, 2016 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27427347

RESUMEN

BACKGROUND: To evaluate the long-term clinical results of below-the-knee percutaneous transluminal angioplasty (BTK-PTA) with or without stenting, in patients with critical limb ischemia (CLI), and to determine factors affecting clinical results including the role of the angiosome concept. METHODS: All patients undergoing primary BTK-PTA from January 2007 to December 2011 were included. Primary patency, assisted patency, limb salvage, survival, and wound healing were assessed using the Kaplan-Meier method. Predictors of patency, limb salvage, survival, and wound healing, including the role of the angiosome theory, were determined using multivariate models. RESULTS: A total of 157 procedures were performed in 139 patients with CLI (Rutherford IV 10.8%; Rutherford V-VI 89.2%). Mean age was 74.2 years and 68.3% were men; 60% had diabetes and 31% renal insufficiency. PTA was confined to the infrapopliteal segment alone in 53.5% of cases. Technical success was 87.9%. Stents were placed in 42.6% of cases. The mean follow-up was 14.7 months (range, 1-67 months). Four-year primary and secondary patency were 51% and 61%, respectively. Limb salvage at 4 years was 68.8%. Complete wound healing was 52% at 4 years. Positive predictors of survival were the absence of renal insufficiency (P < 0.0001) and technical success (P = 0.029). Target vessel occlusion of >50% was a negative predictor of limb salvage (P = 0.0072). Positive predictors of wound healing were technical success (P = 0.0067), the absence of renal insufficiency (P < 0.0001) and continuity between a leg artery and a foot artery (P = 0.02). CONCLUSIONS: BTK-PTA can be performed with favorable long-term results in patients with limited longevity. Secondary interventions may be necessary to maintain target vessel patency. In our experience, the angiosome concept had no impact on clinical success.


Asunto(s)
Angioplastia de Balón/métodos , Isquemia/terapia , Extremidad Inferior/irrigación sanguínea , Modelos Cardiovasculares , Enfermedad Arterial Periférica/terapia , Anciano , Anciano de 80 o más Años , Amputación Quirúrgica , Angioplastia de Balón/efectos adversos , Angioplastia de Balón/instrumentación , Angioplastia de Balón/mortalidad , Enfermedad Crítica , Femenino , Francia , Humanos , Isquemia/diagnóstico , Isquemia/mortalidad , Isquemia/fisiopatología , Estimación de Kaplan-Meier , Recuperación del Miembro , Masculino , Persona de Mediana Edad , Análisis Multivariante , Oportunidad Relativa , Enfermedad Arterial Periférica/diagnóstico , Enfermedad Arterial Periférica/mortalidad , Enfermedad Arterial Periférica/fisiopatología , Modelos de Riesgos Proporcionales , Flujo Sanguíneo Regional , Estudios Retrospectivos , Factores de Riesgo , Stents , Factores de Tiempo , Resultado del Tratamiento , Grado de Desobstrucción Vascular , Cicatrización de Heridas
17.
Ann Vasc Surg ; 31: 99-104, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26631773

RESUMEN

BACKGROUND: The main aim of this study was to compare the 5 years rates of secondary patency of above-knee femoropopliteal revascularizations with autologous veins or prosthetic grafts. The secondary objectives were to compare the rates of primary patency, limb salvage, morbidity, and mortality between the 2 groups. METHODS: This was a single-blind randomized study of noninferiority (ratio 1:1), carried out in 11 centers of vascular surgery with 2 parallel groups between July 2002 and November 2005. Follow-up finished in May 2011. The monitoring protocol included a clinical examination and an ultrasound control at 1 month, 3 and 6 months, then annually. RESULTS: One hundred patients were included and randomized in the study, 52 in the prosthetic group and 48 in the autologous vein group. Four patients randomized in the vein group received a prosthetic graft. No patient was excluded from the analysis. In the in intent-to-treat analysis, the 5 years secondary patency was 84.6% in the prosthetic group (IC 95%, 71.9-93.1) and 70.8% in the autologous vein group (IC 95%: 55.9-83.1), and the difference in secondary patency between the prosthetic and the autologous vein groups was 13.8% (IC 95%, -4.4 to 32.0). In the under treatment analysis, the 5 years secondary patency was 96.2% among patients receiving a prosthesis (IC 95%, 80.4-99.9) and 90.5% among patients receiving an autologous vein (IC 95%, 66.9-98.9), and the difference in the rate of patency between prostheses and veins was 5.7% (IC 95%, -13.2 to 24.6). Although there was no significant difference at 5 years, the death rate and the rate of amputation were higher in the prosthetic group. CONCLUSIONS: Although it is impossible to conclude definitely to the noninferiority of prosthetic bypass compared with venous bypass because of the insufficient number of inclusions, this randomized study nevertheless showed at 5 years the satisfactory results obtained with prostheses compared with autologous vein for above-knee femoropopliteal bypasses.


Asunto(s)
Arteria Femoral/cirugía , Enfermedad Arterial Periférica/cirugía , Arteria Poplítea/cirugía , Venas/trasplante , Anciano , Amputación Quirúrgica , Implantación de Prótesis Vascular/efectos adversos , Implantación de Prótesis Vascular/instrumentación , Implantación de Prótesis Vascular/mortalidad , Constricción Patológica , Femenino , Arteria Femoral/diagnóstico por imagen , Arteria Femoral/fisiopatología , Francia , Humanos , Análisis de Intención de Tratar , Recuperación del Miembro , Masculino , Persona de Mediana Edad , Enfermedad Arterial Periférica/diagnóstico , Enfermedad Arterial Periférica/mortalidad , Enfermedad Arterial Periférica/fisiopatología , Arteria Poplítea/diagnóstico por imagen , Arteria Poplítea/fisiopatología , Flujo Sanguíneo Regional , Reoperación , Factores de Riesgo , Método Simple Ciego , Factores de Tiempo , Trasplante Autólogo , Resultado del Tratamiento , Grado de Desobstrucción Vascular
19.
Ann Vasc Surg ; 29(5): 1015.e1-3, 2015 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-25958119

RESUMEN

Iliac artery major calcifications can compromise kidney graft. First-performed prosthetic arterial bypass from the thoracic aorta to the femoral artery allows secondary kidney transplantation. Four patients were submitted to this procedure. No patient died during the postoperative period or the follow-up. The median time to receive a kidney graft after the arterial surgery was 24 months (4-52). The normalization of the sera creatinine level was 6.4 days (2-15). The median follow-up was 38 months (7-79). In our experience, using lateral side clamping of the descendant thoracic aorta during the proximal implantation of the arterial graft avoids bleeding and visceral abdominal ischemia. The secondary performed kidney graft is safe on a very available arterial conduit.


Asunto(s)
Aorta Torácica/cirugía , Arteriopatías Oclusivas/cirugía , Arteria Femoral/cirugía , Arteria Ilíaca , Trasplante de Riñón/métodos , Stents , Procedimientos Quirúrgicos Vasculares/métodos , Anciano , Anastomosis Quirúrgica/métodos , Arteriopatías Oclusivas/complicaciones , Estudios de Seguimiento , Humanos , Fallo Renal Crónico/complicaciones , Fallo Renal Crónico/cirugía , Masculino , Persona de Mediana Edad
20.
Ann Vasc Surg ; 29(6): 1315.e1-2, 2015 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-25958120

RESUMEN

The need to treat an abdominal aortic aneurysm (AAA) in kidney transplanted patient is a rare event. To date, no method to protect the kidney during the aneurysm treatment has been identified as undeniably relevant. On the other hand, the advantage of endovascular treatment of the aneurysm (EVAR) is to avoid transplanted kidney injury. Unfortunately, EVAR is not always available leading to open repair and then aortic cross clamping. We report here 3 cases of AAA open repair in kidney transplanted patients using a temporary axillofemoral bypass to protect the renal function.


Asunto(s)
Aneurisma de la Aorta Abdominal/cirugía , Arteria Axilar/cirugía , Implantación de Prótesis Vascular , Arteria Femoral/cirugía , Trasplante de Riñón , Anciano , Aneurisma de la Aorta Abdominal/diagnóstico , Aneurisma de la Aorta Abdominal/fisiopatología , Aortografía/métodos , Arteria Axilar/fisiopatología , Femenino , Arteria Femoral/fisiopatología , Supervivencia de Injerto , Humanos , Masculino , Persona de Mediana Edad , Flujo Sanguíneo Regional , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
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