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1.
Ophthalmic Plast Reconstr Surg ; 40(1): 11-17, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-37486339

RESUMEN

PURPOSE: There is no known optimal treatment for primary periocular orofacial granulomatosis (PPOFG), a disorder that results in periocular edema. This case series and systematic review identifies management strategies and their reported improvement. METHODS: Systematic review and case series. PubMed and MEDLINE databases were searched following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines to identify published cases of PPOFG. Cases were included when edema involved the periocular tissues and when a biopsy was interpreted to be PPOFG. Cases were excluded when edema did not involve the periocular tissues or when the edema was secondary to another process. The electronic medical records of the pathology department were studied to identify cases that were in keeping with PPOFG. The clinical charts were examined to confirm the diagnosis and provide a local case series. RESULTS: There are 38 published cases of PPOFG. An additional 9 cases were identified locally. These cases were combined and analyzed. Most PPOFG has eyelid swelling in isolation, without other facial swelling (36/47; 76.6%). It is most commonly a bilateral disease (30/47; 63.8%). Fissured tongue and facial nerve palsy occur, just as they do in other cases of orofacial granulomatosis. Treatment with surgical debulking or intralesional steroids resulted in high rates of symptomatic improvement of eyelid swelling, but recurrences were common. CONCLUSIONS: In light of no curative or highly successful treatment currently available, intralesional steroids and/or surgical debulking are therapies in the treatment of eyelid swelling associated with PPOFG that demonstrate reasonable short- and medium-term results. There is no established therapy that can offer disease remission or long-term symptom improvement.


Asunto(s)
Parálisis Facial , Granulomatosis Orofacial , Humanos , Granulomatosis Orofacial/terapia , Granulomatosis Orofacial/tratamiento farmacológico , Edema/diagnóstico , Biopsia , Esteroides/uso terapéutico
3.
Saudi J Ophthalmol ; 26(2): 177-9, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-23960989

RESUMEN

Orofacial granulomatosis (OFG) is an uncommon but increasingly recognized disease of unknown etiology. The typical presentation is chronic swelling of the perioral soft tissue, but eyelid edema can be the sole manifestation. Terminology of this disease can be confusing as it may also be referred to as granulomatous cheilitis and a monosymptomatic presentation of Melkersson-Rosenthal syndrome (MRS). Crohn's disease and sarcoidosis should also be considered in the differential as the histopathology can be similar. Corticosteroids are the mainstay of treatment but can lack efficacy. Atypical presentations and the possibility of systemic disease involvement can further challenge the management. We describe an unusual case in which OFG manifests solely as chronic eyelid swelling. This 69-year old Asian female patient had a delayed diagnosis that responded well to intralesional corticosteroid injection with surgical skin reduction. In addition to describing this unusual presentation of OFG, we review the relevant literature and evaluate the current terminology used to describe this entity.

4.
Ophthalmic Plast Reconstr Surg ; 23(2): 126-9, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17413627

RESUMEN

PURPOSE: To describe the association between entropion and pediatric facial nerve paralysis in the pediatric population. METHODS: A retrospective case series was collected from 5 pediatric patients who required surgical correction for symptomatic entropion with a history of facial nerve palsy. RESULTS: All 5 patients presented with epiphora and punctate keratopathy. Following surgical correction of the entropion, all ocular symptoms resolved. CONCLUSIONS: To the best of our knowledge, this is the first report linking facial nerve paralysis with entropion in the pediatric population. Ophthalmologists and pediatricians should consider this in the evaluation of children with craniofacial abnormalities and facial nerve paralysis.


Asunto(s)
Entropión/etiología , Párpados/patología , Parálisis Facial/complicaciones , Niño , Preescolar , Enfermedades de la Córnea/etiología , Enfermedades de la Córnea/cirugía , Entropión/cirugía , Párpados/cirugía , Parálisis Facial/cirugía , Femenino , Humanos , Lactante , Enfermedades del Aparato Lagrimal/etiología , Enfermedades del Aparato Lagrimal/cirugía , Masculino , Músculos Oculomotores/patología , Músculos Oculomotores/cirugía , Estudios Retrospectivos
5.
Artículo en Inglés | MEDLINE | ID: mdl-16418660

RESUMEN

PURPOSE: To assess the efficacy of bioresorbable mesh in reconstruction of orbitocranial deformities. METHODS: A retrospective case series evaluating 6 orbits of 6 patients, ages 12 to 70 years old, with large multicontoured orbitocranial defects that were repaired using bioresorbable macroporous mesh. Both functional (presence of diplopia, ocular motility, exophthalmometry, and vertical globe position) and cosmetic outcomes were evaluated. RESULTS: Follow-up time ranged from 20 to 48 months (mean, 29.1 months). After surgery, all patients reported cosmetically pleasing results. Diplopia resolved in all patients. Ocular motility, exophthalmos, enophthalmos, and vertical globe positioning improved in all patients. One patient had new onset of mild enophthalmos and hypoglobus after surgery. No cases of implant exposure or instability occurred. Complications included one patient with skin breakdown over a previous site of irradiation and one patient with ptosis requiring surgical correction. CONCLUSIONS: Bioresorbable macroporous mesh combined with bone grafts is a useful and accurate method to reconstruct complex multicontoured orbitocranial defects.


Asunto(s)
Implantes Absorbibles , Modelos Anatómicos , Enfermedades Orbitales/cirugía , Implantes Orbitales , Procedimientos de Cirugía Plástica/métodos , Implantación de Prótesis/instrumentación , Mallas Quirúrgicas , Adolescente , Anciano , Niño , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Orbitales/diagnóstico por imagen , Diseño de Prótesis , Estudios Retrospectivos , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
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