Fulminant Reversible Cerebral Vasoconstriction Syndrome in Breakthrough COVID 19 Infection.

COVID 19 infection continues to afflict people worldwide. Neurological complications of COVID infection are common. We report a case of fulminant reversible cerebrovascular constriction syndrome (RCVS) in a patient with breakthrough COVID 19 infection who was fully vaccinated. A 64 year old lady, fully vaccinated 2 months back, presented with headache, drowsiness, partial seizures, visual impairment and quadriplegia. Her nasopharyngeal swab was tested positive for SARS COV2 on real time PCR assay. MRI brain FLAIR images showed multifocal hyperintensities with MR angiogram showing arterial vasoconstriction suggestive of RCVS. Despite initiation of nimodipine, patient's symptoms worsened and she succumbed to sepsis. RCVS following COVID infection has been reported to have a benign outcome. However, despite vaccination, fulminant RCVS following a breakthrough COVID infection was observed in our patient.

Carpal Boss: A Case Series of a Radiological Enigma in Dorsal Wrist Pathology.

Carpal boss, a relatively rare and often underdiagnosed condition, is characterized by a bony protuberance at the dorsal aspect of the carpometacarpal (CMC) joint. It is commonly misdiagnosed due to its nonspecific clinical presentation, which can mimic other conditions, such as ganglion cysts or fractures. This case series aims to document and analyze the clinical presentations and radiological findings of three patients diagnosed with carpal boss, highlighting the importance of advanced imaging techniques in accurate diagnosis and management. A case series was conducted at Tenet Diagnostics, Bengaluru, Karnataka, involving three patients with dorsal wrist pain and swelling at the CMC joint. All patients underwent clinical evaluation followed by imaging studies using 3T magnetic resonance imaging (MRI) (United Imaging, Shanghai, China) and 32-slice computed tomography (CT) (Siemens Somatom Go; Siemens Healthineers, Munich, Germany). The MRI sequences included T1-weighted and proton density (PD) fat-saturated images, while CT imaging focused on axial and sagittal sections to assess bony structures. All three patients were diagnosed with carpal boss based on imaging findings. MRI revealed hypertrophied bony protuberances at the bases of the second and third metacarpal bones, forming pseudoarthrosis with associated osteoarthritic changes. CT imaging confirmed these findings, providing high-resolution views of the bony abnormalities. Combining MRI and CT was crucial in differentiating carpal boss from other potential diagnoses, such as ganglion cysts or fractures. This case series underscores the importance of advanced imaging modalities, such as MRI and CT, in diagnosing carpal boss. Accurate and early diagnosis can prevent mismanagement and guide appropriate treatment strategies, improving patient outcomes. Increased awareness of carpal boss among clinicians and radiologists is essential for promptly recognizing and managing this condition.

Association between chronic periodontitis and vasculogenic erectile dysfunction.

BACKGROUND: Erectile dysfunction (ED) and chronic periodontitis (CP) share common risk factors. There is only one report on the association between ED and CP. Thus, the aim of this study is to find the association between vasculogenic ED and CP. METHODS: A total of 70 patients (mean age: 35.3 ± 3.64 years) clinically diagnosed with ED were included in the study. They were given the Sexual Health Inventory for Men Questionnaire and subjected to colored penile Doppler ultrasound. Periodontal parameters of probing depth and periodontal attachment level were recorded. Five patients with ED and CP were selected randomly for cardiac color Doppler to assess the integrity. RESULTS: Among the selected vasculogenic patients with ED, mild-to-moderate vasculogenic ED showed the highest prevalence, whereas prevalence for CP among all vasculogenic patients with ED was highest among severe ED (81.8%). Association of CP and vasculogenic ED was found to be correlated positively, but it showed no statistical significance. Two of five patients were found to have vascular insufficiency. CONCLUSIONS: It can be hypothesized that an association exists between vasculogenic ED and CP in young males. However, a large-scale study with confounder analysis and a longitudinal follow-up is warranted.