Detalles de la búsqueda
1.
Nanoparticles Bearing TSH Receptor Protein and a Tolerogenic Molecule Do Not Induce Immune Tolerance but Exacerbate Thyroid Autoimmunity in hTSHR/NOD.H2h4 Mice.
J Immunol
; 202(9): 2570-2577, 2019 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30944161
2.
Peri-tumor administration of controlled release anti-CTLA-4 synergizes with systemic anti-PD-1 to induce systemic antitumor immunity while sparing autoimmune toxicity.
Cancer Immunol Immunother
; 69(9): 1737-1749, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32333082
3.
Reflections on Thyroid Autoimmunity: A Personal Overview from the Past into the Future.
Horm Metab Res
; 50(12): 840-852, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30357776
4.
Critical Differences between Induced and Spontaneous Mouse Models of Graves' Disease with Implications for Antigen-Specific Immunotherapy in Humans.
J Immunol
; 197(12): 4560-4568, 2016 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27913646
5.
A unique mouse strain that develops spontaneous, iodine-accelerated, pathogenic antibodies to the human thyrotrophin receptor.
J Immunol
; 194(9): 4154-61, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25825442
6.
Discoveries in Thyroid Autoimmunity in the Past Century.
Thyroid
; 33(3): 278-286, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35765927
7.
Evidence that the thyroid-stimulating hormone (TSH) receptor transmembrane domain influences kinetics of TSH binding to the receptor ectodomain.
J Biol Chem
; 286(8): 6219-24, 2011 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-21190937
8.
Insight into Graves' hyperthyroidism from animal models.
Endocr Rev
; 26(6): 800-32, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15827111
9.
The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction.
Mol Endocrinol
; 22(5): 1171-82, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-18218728
10.
A transgenic mouse that spontaneously develops pathogenic TSH receptor antibodies will facilitate study of antigen-specific immunotherapy for human Graves' disease.
Endocrine
; 66(2): 137-148, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31560118
11.
A Mouse Thyrotropin Receptor A-Subunit Transgene Expressed in Thyroiditis-Prone Mice May Provide Insight into Why Graves' Disease Only Occurs in Humans.
Thyroid
; 29(8): 1138-1146, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31184281
12.
Identification of key amino acid residues in a thyrotropin receptor monoclonal antibody epitope provides insight into its inverse agonist and antagonist properties.
Endocrinology
; 149(7): 3427-34, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18388191
13.
Shared and unique susceptibility genes in a mouse model of Graves' disease determined in BXH and CXB recombinant inbred mice.
Endocrinology
; 149(4): 2001-9, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18162518
14.
Aberrant Iodine Autoregulation Induces Hypothyroidism in a Mouse Strain in the Absence of Thyroid Autoimmunity.
J Endocr Soc
; 2(1): 63-76, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29379895
15.
Thyroid Hemiagenesis in a Thyroiditis Prone Mouse Strain.
Eur Thyroid J
; 7(4): 187-192, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30283736
16.
Structure of a Thyrotropin Receptor Monoclonal Antibody Variable Region Provides Insight into Potential Mechanisms for its Inverse Agonist Activity.
Thyroid
; 28(7): 933-940, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29845889
17.
Suppression of thyrotropin receptor constitutive activity by a monoclonal antibody with inverse agonist activity.
Endocrinology
; 148(5): 2375-82, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17272389
18.
The link between Graves' disease and Hashimoto's thyroiditis: a role for regulatory T cells.
Endocrinology
; 148(12): 5724-33, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17823263
19.
The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim.
J Clin Invest
; 111(12): 1897-904, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12813025
20.
Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor.
J Clin Invest
; 110(2): 209-17, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12122113