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Epithelioid sarcoma is a very rare tumor, comprising less than 1% of all soft tissue sarcoma. Due to its rarity and benign presentation, it is often misdiagnosed. We present a case of epithelioid sarcoma mimicking coronary artery bypass grafting post-operative keloid. Current literature suggests the management for epithelioid sarcoma to include surgery and adjuvant radiation. In this patient, chest wall reconstruction was done using titanium mesh and muscle flaps. Post-operative radiation was given and computerized tomography scan was evaluated 3 months after reconstruction.
RESUMEN
BACKGROUND: Cardioplegia is an integral part of myocardial protection. The superiority of blood cardioplegia in adult patients has been reported. However, this is yet to be studied in cyanotic pediatric patients. METHODS: A randomized open-label trial was conducted in 70 patients with tetralogy of Fallot. They were divided into two groups: 35 patients had crystalloid cardioplegia (controls), and 35 had blood cardioplegia. Lactate and coronary oxygen extraction in arterial blood and the coronary sinus were measured immediately after cessation of cardiopulmonary bypass, 15 and 30 min later. Postoperative mortality, major adverse cardiac events, mechanical ventilation time, inotrope administration, arrhythmias, right ventricular function, intensive care unit and hospital length of stay were observed. RESULTS: There were no significant differences in clinical outcomes or lactate levels. There was a significant difference in coronary oxygen extraction immediately and 15 min after cessation of cardiopulmonary bypass ( p = 0.038, p = 0.015). CONCLUSION: Blood cardioplegia gave a better postoperative oxygen extraction value but there were no differences in myocardial damage or clinical outcome between the two groups.
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Procedimientos Quirúrgicos Cardíacos , Soluciones Cardiopléjicas/uso terapéutico , Puente Cardiopulmonar , Paro Cardíaco Inducido/métodos , Compuestos de Potasio/uso terapéutico , Tetralogía de Fallot/cirugía , Adolescente , Adulto , Biomarcadores/sangre , Procedimientos Quirúrgicos Cardíacos/efectos adversos , Soluciones Cardiopléjicas/efectos adversos , Puente Cardiopulmonar/efectos adversos , Niño , Preescolar , Cianosis/sangre , Cianosis/etiología , Femenino , Paro Cardíaco Inducido/efectos adversos , Humanos , Indonesia , Lactante , Recién Nacido , Ácido Láctico/sangre , Masculino , Oxígeno/sangre , Complicaciones Posoperatorias/etiología , Compuestos de Potasio/efectos adversos , Factores de Riesgo , Tetralogía de Fallot/sangre , Tetralogía de Fallot/complicaciones , Tetralogía de Fallot/diagnóstico por imagen , Factores de Tiempo , Resultado del Tratamiento , Adulto JovenRESUMEN
Introduction Myocardial protection is vital to ensure successful open heart surgery. Cardioplegic solution is one method to achieve good myocardial protection. Inevitably, ischemia-reperfusion injury occurs with aortic crossclamping. Histidine-tryptophan-ketoglutarate solution is a frequently used cardioplegia for complex congenital heart surgery. We postulated that addition of terminal warm blood cardioplegia before removal of the aortic crossclamp might improve myocardial protection. Method A randomized controlled trial was conducted on 109 cyanotic patients aged, 1 to 5 years who underwent complex biventricular repair. They were divided into a control group of 55 patients who had histidine-tryptophan-ketoglutarate only and a treatment group of 54 who had histidine-tryptophan-ketoglutarate with terminal warm blood cardioplegia. Endpoints were clinical parameters, troponin I levels, and caspase-3 as an apoptosis marker. Results The incidence of low cardiac output syndrome was 34%, with no significant difference between groups (35.2% vs. 33.3%, p = 0.84). The incidence of arrhythmias in our treatment group was lower compared to the control group (36% vs. 12%, p = 0.005). Troponin I and caspase-3 results did not show any significant differences between groups. For cases with Aristotle score ≥ 10, weak expression of caspase-3 in the treatment group post-cardiopulmonary bypass was lower compared to the control group. Conclusion For complex congenital cardiac surgery, the addition of terminal warm blood cardioplegia does not significantly improve postoperative clinical or metabolic markers.
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Soluciones Cardiopléjicas/administración & dosificación , Paro Cardíaco Inducido/métodos , Cardiopatías Congénitas/cirugía , Temperatura , Apoptosis , Arritmias Cardíacas/etiología , Biomarcadores/sangre , Gasto Cardíaco Bajo/etiología , Soluciones Cardiopléjicas/efectos adversos , Caspasa 3/análisis , Preescolar , Femenino , Glucosa/administración & dosificación , Glucosa/efectos adversos , Paro Cardíaco Inducido/efectos adversos , Cardiopatías Congénitas/diagnóstico por imagen , Cardiopatías Congénitas/fisiopatología , Humanos , Indonesia , Lactante , Masculino , Manitol/administración & dosificación , Manitol/efectos adversos , Miocardio/química , Miocardio/patología , Cloruro de Potasio/administración & dosificación , Cloruro de Potasio/efectos adversos , Procaína/administración & dosificación , Procaína/efectos adversos , Factores de Tiempo , Resultado del Tratamiento , Troponina I/sangreRESUMEN
Isolated saccular compared to fusiform aneurysm is considered to be a rare entity with challenges of its own. A 62-year-old female was diagnosed with a case of saccular aneurysm and penetrating atherosclerotic ulcer of the aortic arch. Additionally, she also had one vessel coronary artery disease and type B abdominal aortic dissection. She was then managed with open aortic arch repair and coronary artery bypass grafting. If required, elective endovascular repair will be done for the abdominal aorta on a later date.