Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 16 de 16
Filtrar
Más filtros

Tipo del documento
País de afiliación
Intervalo de año de publicación
1.
Surg Endosc ; 36(8): 6319-6325, 2022 08.
Artículo en Inglés | MEDLINE | ID: mdl-35608699

RESUMEN

BACKGROUND: About 4 years ago, we described the pure endoscopic cervical approach to posterior mediastinum parathyroid adenomas, which we called the "prevertebral cervical approach". At that time, we had operated on three patients and did not have enough quality videos to demonstrate this approach. After broadening our experience, we present our results and show this technique through a video. METHODS: From June 2015 to January 2021, information on patients undergoing the prevertebral cervical approach was obtained from a specific prospective database, including clinical presentation, biochemistry, preoperative imaging, surgical approach and patient outcomes. The step by step technique is described for both right- and left-sided adenomas, by means of a short video clip. RESULTS: Ten patients were operated on using this technique. Seven adenomas were right-sided and three were left-sided. The mean surgical time was 33 ± 7 min. There were neither intraoperative nor major postoperative complications. Seven patients presented with a slight subcutaneous emphysema, which did not cause complaints. All patients were discharged the day after surgery, except for one patient with a previous open neck removal of four glands due to secondary hyperparathyroidism, which required calcium replacement. Calcium and parathyroid hormone levels were normalised in the other nine patients after surgery. One patient experienced a transient recurrent laryngeal nerve injury which was spontaneously resolved within 1 month. No permanent recurrent laryngeal nerve injury was found. The postoperative cosmetic outcomes were excellent. CONCLUSION: In our experience, the pure cervical endoscopic approach has shown a high feasibility and short operation time, with excellent postoperative results regarding patient comfort, length of stay and disease cure. This approach also offers a very reasonable procedure cost, and may result in a less aggressive surgical option when compared with thoracic approaches.


Asunto(s)
Adenoma , Neoplasias de las Paratiroides , Traumatismos del Nervio Laríngeo Recurrente , Adenoma/complicaciones , Adenoma/cirugía , Calcio , Humanos , Mediastino/cirugía , Glándulas Paratiroides , Hormona Paratiroidea , Neoplasias de las Paratiroides/complicaciones , Neoplasias de las Paratiroides/diagnóstico por imagen , Neoplasias de las Paratiroides/cirugía , Paratiroidectomía/métodos
2.
Rev Esp Enferm Dig ; 109(6): 406-413, 2017 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-28508661

RESUMEN

INTRODUCTION: Post-transplant lymphoproliferative syndrome (PTLD) is a rare and potentially life-threatening complication after liver transplantation. The aim of this study was to analyze the clinicopathologic features related to PTLD in a single institution after liver transplantation. METHODS: Observational study where we have retrospectively analyzed 851 cases who underwent liver transplantation. Ten cases have developed PTLD. Their clinical-pathological characteristics and the treatment received have been analyzed. RESULTS: PTLD incidence was 1.2% (10/851). The mean time from liver transplantation to PTLD diagnosis was 36 months (range 1.2 to 144 months). PTLD localization was extranodal in all cases, the most frequent location being intestinal. Seven cases showed a monomorphic lymphoma which in all cases was differentiated B cell lymphomas. Fifty per cent of the series were seropositive for Epstein-Barr virus. Five patients were alive at the time of the review. Among these patients, we observed three cases of complete remission and two cases of disease stabilization. The death rate was higher in the first year after diagnosis of PTLD. CONCLUSION: PTLD is a rare complication after liver transplantation, but it may pose a threat to the life of a liver transplant recipient. It is essential to identify patients at risk, to establish an early diagnosis and treatment that can change the outcome of the disease.


Asunto(s)
Trasplante de Hígado/efectos adversos , Trastornos Linfoproliferativos/etiología , Trastornos Linfoproliferativos/terapia , Adulto , Anciano , Diagnóstico Precoz , Femenino , Humanos , Incidencia , Trasplante de Hígado/mortalidad , Trastornos Linfoproliferativos/mortalidad , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/terapia , Estudios Retrospectivos , Análisis de Supervivencia
3.
Rev Esp Enferm Dig ; 107(7): 417-22, 2015 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-26140634

RESUMEN

INTRODUCTION: The anatomical variants of the hepatic artery may have important implications for pancreatic cancer surgery. The aim of our study is to compare the outcome following a pancreatoduodenectomy (PD) in patients with or without a variant hepatic artery arising from superior mesenteric artery. MATERIAL AND METHODS: We reviewed 151 patients with periampullary tumoral pathology. All patients underwent oncological PD between January 2005 and February 2012. Our series was divided into two groups: Group A: Patients with a hepatic artery arising from superior mesenteric artery; and Group B: Patients without a hepatic artery arising from superior mesenteric artery. We expressed the results as mean +/- standard deviation for continuous variables and percentages for qualitative variables. Statistical tests were considered significant if p < 0.05. RESULTS: We identified 11 patients with a hepatic artery arising from superior mesenteric artery (7.3%). The most frequent variant was an aberrant right hepatic artery (n = 7), following by the accessory right hepatic artery (n = 2) and the common hepatic artery trunk arising from the superior mesenteric artery (n = 2). In 73% of cases the diagnosis of the variant was intraoperative. R0 resection was performed in all patients with a hepatic artery arising from superior mesenteric artery. There were no significant differences in the tumor resection margins and the incidence of postoperative complications. CONCLUSION: Oncological PD is feasible by the presence of a hepatic artery arising from superior mesenteric artery. The complexity of having it does not seem to influence in tumor resection margins, complications and survival.


Asunto(s)
Arteria Hepática/anomalías , Arteria Mesentérica Superior/anomalías , Neoplasias Pancreáticas/cirugía , Pancreaticoduodenectomía , Malformaciones Vasculares/complicaciones , Adenocarcinoma/complicaciones , Adenocarcinoma/cirugía , Adulto , Anciano , Neoplasias de los Conductos Biliares/complicaciones , Neoplasias de los Conductos Biliares/cirugía , Colangiocarcinoma/complicaciones , Colangiocarcinoma/cirugía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Tumores Neuroendocrinos/complicaciones , Tumores Neuroendocrinos/cirugía , Pancreatectomía , Neoplasias Pancreáticas/complicaciones , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Estudios Retrospectivos , Resultado del Tratamiento
4.
Cir Esp ; 93(8): 530-5, 2015 Oct.
Artículo en Inglés, Español | MEDLINE | ID: mdl-25659535

RESUMEN

INTRODUCTION: Dynamic endoanal ultrasound has emerged in recent years as a test that could replace the now existing tests in the diagnosis of pelvic floor disorders. The aim of this paper is to determine the usefulness of echodefecography in the diagnosis and evaluation of patients with symptoms of anorrectal obstruction, and show the results obtained after its implementation in a pelvic floor unit, as a complementary tool that could replace conventional defecography. METHODS: In this retrospective study we analyzed 66 patients with a mean age of 55 years (19-83), 61 women (92%). All dynamic ultrasound was performed in 3 dimensions and was correlated with symptoms and physical findings in the consultation. A descriptive and inferential study was performed to find a kappa correlation between physical examination and echodefecography. RESULTS: The reasons for consultation were: Anorrectal obstruction syndrome 36 patients (54.5%), pelvic organ prolapse 27 patients (40.9%), and anorrectal obstruction syndrome along with pelvic organ prolapse 3 patients (4.5%). The correlation of the 2 groups indicated that echodefecography diagnosed more patients with grade III rectocele, enteroceles, and anismus than the combination of scan-ultrasound-manometry-proctoscopy (Kappa 0.26, 0.38 and 0.21, 95% CI: from 0,07 to 1.00, 0.15 to 1.00 and from 0.12 to 1.00, respectively) (P<.001). Conversely, echodefecography diagnosed less perineal descense (Kappa 0.28, 95% CI: 0.12 to 1.00). CONCLUSIONS: Dynamic anal ultrasonography may have a role as a complementary test in patients with pelvic floor disorders, achieving diagnoses that would go undetected by inspection, physical examination and manometry.


Asunto(s)
Imagenología Tridimensional , Trastornos del Suelo Pélvico/diagnóstico por imagen , Diafragma Pélvico/diagnóstico por imagen , Ultrasonografía/métodos , Adulto , Anciano , Anciano de 80 o más Años , Defecografía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto Joven
5.
Surg Endosc ; 27(11): 4347-53, 2013 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-23846366

RESUMEN

BACKGROUND: The current tendency to use increasingly less aggressive procedures has facilitated the development of new minimally invasive techniques. In this context, single-port (SP) access procedures can become an alternative to the conventional laparoscopic approach. METHODS: A total of 22 morbidly obese patients were submitted to pure SP Roux-en-Y gastric bypass without additional ports. Selection for this approach was based on distance from the xiphoid to the umbilicus less than 28 cm, body mass index (BMI) lower than 50 kg/m(2), and preferably peripheral obesity. Access to the cavity was obtained through a single transverse, transumbilical incision, with placement of a SILS Port device. RESULTS: The mean age of the patients was 41 ± 8.98 years, and 95 % of the patients were women. The mean BMI of the series was 42.68 ± 2.28 kg/m(2), and the mean body weight was 111.34 ± 10.66 kg. Surgery was performed successfully in all cases through a transumbilical incision with a mean length of 26.68 ± 5.27 mm. The mean surgical time was 114.05 ± 21 min, and the mean hospital stay was 3.27 ± 1.01 days. No intraoperative or immediate postoperative deaths or complications occurred. The median postoperative BMI during a mean follow-up period of 12 months was 28 kg/m(2) (range, 18-35 kg/m(2)). The median weight loss was 39 kg, and the percentage loss of excess body weight was 86 %. In relation to improvement of the comorbidities, two of the three patients with arterial hypertension showed normalization of their blood pressure values. Likewise, the blood glucose levels were corrected in two of the three diabetic patients, as well as in the patient with altered fasting blood glucose. CONCLUSIONS: Single-port Roux-en-Y gastric bypass surgery seems to be a safe, viable, and reproducible technique, but randomized studies involving larger patient series and longer follow-up periods are needed to compare the SP access and the multiple-port laparoscopic approach.


Asunto(s)
Derivación Gástrica/instrumentación , Derivación Gástrica/métodos , Procedimientos Quirúrgicos Mínimamente Invasivos/instrumentación , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Obesidad Mórbida/cirugía , Adulto , Índice de Masa Corporal , Femenino , Estudios de Seguimiento , Humanos , Laparoscopía , Tiempo de Internación , Masculino , Instrumentos Quirúrgicos , Resultado del Tratamiento , Ombligo/cirugía
8.
Emergencias ; 30(4): 261-264, 2018.
Artículo en Inglés, Español | MEDLINE | ID: mdl-30033700

RESUMEN

OBJECTIVES: To analyze the clinical presentation, management, and outcome of acute appendicitis (AA) in pregnant and nonpregnant women of childbearing age. MATERIAL AND METHODS: Descriptive study of 2 cohorts of women (pregnant -P- and nonpregnant -NP-). The women, who were matched according to risk factors, were included when they underwent an emergency appendectomy based on clinical suspicion of AA. We recorded age, medical history, clinical presentation, management, and outcome. Pregnant women were classified according to gestational age of the fetus (trimester). RESULTS: . We included 153 women (51 P, 102 NP). The mean (SD) age was 28.8 (6.5) years (P women, 29.7 [5.8] years; NP, 28.3 [6.8]; P=.242). The mean Alvarado score was 7.1 (1.6) (P, 6.7 [1.7]; NP, 7.3 [1.5]; P=.016). The rate of complicated AA was higher in P (19.6%) than NP (2.9%) women (P<.001). Pregnancy was also associated with higher rates of surgical wound infection (P, 14.0%; NP, 3.0%; P=.016) and a longer mean hospital stay (P, 5.1 [4.8] days; NP, 1.7 [1.0]; P<.001). In the third trimester of P, poorer outcomes were recorded in relation to these risks (P=.031; P=.003, and P<.001, respectively). CONCLUSION: The atypical clinical presentation of AA during pregnancy makes diagnosis difficult and may lead to a higher incidence of complicated AA and surgical wound infection as well as longer hospital stays, particularly when AA presents in the third trimester.


OBJETIVO: Evaluar la presentación clínica, el manejo y los resultados de la apendicitis aguda (AA) en mujeres de edad fértil en función de la presencia de embarazo y su estado evolutivo. METODO: Estudio observacional de dos cohortes (gestantes [G] y no gestantes [NG]), apareadas según técnicas de propensión de riesgo, que incluyó mujeres adultas en edad fértil sometidas a apendicectomía urgente por la sospecha clínica de AA. Se recogieron variables relacionadas con la edad, los antecedentes personales, la presentación clínica, el manejo y los resultados. Se realizó un análisis según la presencia de embarazo y el trimestre de gestación. RESULTADOS: Se incluyeron 153 mujeres (51 G y 102 NG). La edad media fue de 28,8 (DE 6,5) años (G: 29,7 [DE 5,8] vs NG: 28,3 [DE 6,8]; p = 0,242). La puntuación de la escala de Alvarado fue de 7,1 (DE 1,6) (G: 6,7 [DE 1,7] vs NG: 7,3 [DE 1,5]; p = 0,016). Las G presentaron mayor incidencia de AA complicada (G: 19,6% vs NG: 2,9%; p < 0,001), infección del sitio quirúrgico (G: 14,0% vs NG: 3,0; p = 0,016), estancia media (G: 5,1 [DE 4,8] vs NG: 1,7 [DE 1,0]; p < 0,001). Los resultados fueron peores, entre las G del tercer trimestre (p = 0,031, p = 0,003 y p < 0,001, respectivamente). CONCLUSIONES: La presentación clínica atípica de la AA durante el embarazo dificulta su diagnóstico, lo que podría traducirse en una mayor incidencia de AA complicada, infección del sitio quirúrgico y tiempo de estancia hospitalaria, sobre todo si se presenta la AA durante el tercer trimestre de gestación.


Asunto(s)
Apendicitis , Complicaciones del Embarazo , Enfermedad Aguda , Adulto , Apendicectomía , Apendicitis/complicaciones , Apendicitis/diagnóstico , Apendicitis/cirugía , Femenino , Humanos , Tiempo de Internación/estadística & datos numéricos , Análisis por Apareamiento , Embarazo , Complicaciones del Embarazo/diagnóstico , Complicaciones del Embarazo/cirugía , Estudios Retrospectivos , Factores de Riesgo , Infección de la Herida Quirúrgica/etiología , Resultado del Tratamiento
9.
World J Gastroenterol ; 24(7): 794-809, 2018 Feb 21.
Artículo en Inglés | MEDLINE | ID: mdl-29467550

RESUMEN

AIM: To assess the viability of orthotopic and heterotopic patient-derived pancreatic cancer xenografts implanted into nude mice. METHODS: This study presents a prospective experimental analytical follow-up of the development of tumours in mice upon implantation of human pancreatic adenocarcinoma samples. Specimens were obtained surgically from patients with a pathological diagnosis of pancreatic adenocarcinoma. Tumour samples from pancreatic cancer patients were transplanted into nude mice in three different locations (intraperitoneal, subcutaneous and pancreatic). Histological analysis (haematoxylin-eosin and Masson's trichrome staining) and immunohistochemical assessment of apoptosis (TUNEL), proliferation (Ki-67), angiogenesis (CD31) and fibrogenesis (α-SMA) were performed. When a tumour xenograft reached the target size, it was re-implanted in a new nude mouse. Three sequential tumour xenograft generations were generated (F1, F2 and F3). RESULTS: The overall tumour engraftment rate was 61.1%. The subcutaneous model was most effective in terms of tissue growth (69.9%), followed by intraperitoneal (57.6%) and pancreatic (55%) models. Tumour development was faster in the subcutaneous model (17.7 ± 2.6 wk) compared with the pancreatic (23.1 ± 2.3 wk) and intraperitoneal (25.0 ± 2.7 wk) models (P = 0.064). There was a progressive increase in the tumour engraftment rate over successive generations for all three models (F1 28.1% vs F2 71.4% vs F3 80.9%, P < 0.001). There were no significant differences in tumour xenograft differentiation and cell proliferation between human samples and the three experimental models among the sequential generations of tumour xenografts. However, a progressive decrease in fibrosis, fibrogenesis, tumour vascularisation and apoptosis was observed in the three experimental models compared with the human samples. All three pancreatic patient-derived xenograft models presented similar histological and immunohistochemical characteristics. CONCLUSION: In our experience, the faster development and greatest number of viable xenografts could make the subcutaneous model the best option for experimentation in pancreatic cancer.


Asunto(s)
Adenocarcinoma/patología , Neoplasias Pancreáticas/patología , Investigación Biomédica Traslacional/métodos , Trasplante Heterólogo/métodos , Ensayos Antitumor por Modelo de Xenoinjerto/métodos , Adenocarcinoma/cirugía , Anciano , Anciano de 80 o más Años , Animales , Femenino , Humanos , Masculino , Ratones , Ratones Desnudos , Persona de Mediana Edad , Páncreas/patología , Páncreas/cirugía , Neoplasias Pancreáticas/cirugía , Estudios Prospectivos , Factores de Tiempo , Neoplasias Pancreáticas
11.
Emergencias (Sant Vicenç dels Horts) ; 30(4): 261-264, ago. 2018. tab
Artículo en Español | IBECS (España) | ID: ibc-180061

RESUMEN

Objetivo: Evaluar la presentación clínica, el manejo y los resultados de la apendicitis aguda (AA) en mujeres de edad fértil en función de la presencia de embarazo y su estado evolutivo. Método: Estudio observacional de dos cohortes (gestantes [G] y no gestantes [NG]), apareadas según técnicas de propensión de riesgo, que incluyó mujeres adultas en edad fértil sometidas a apendicectomía urgente por la sospecha clínica de AA. Se recogieron variables relacionadas con la edad, los antecedentes personales, la presentación clínica, el manejo y los resultados. Se realizó un análisis según la presencia de embarazo y el trimestre de gestación. Resultados: Se incluyeron 153 mujeres (51 G y 102 NG). La edad media fue de 28,8 (DE 6,5) años (G: 29,7 [DE 5,8] vs NG: 28,3 [DE 6,8]; p = 0,242). La puntuación de la escala de Alvarado fue de 7,1 (DE 1,6) (G: 6,7 [DE 1,7] vs NG: 7,3 [DE 1,5]; p = 0,016). Las G presentaron mayor incidencia de AA complicada (G: 19,6% vs NG: 2,9%; p < 0,001), infección del sitio quirúrgico (G: 14,0% vs NG: 3,0; p = 0,016), estancia media (G: 5,1 [DE 4,8] vs NG: 1,7 [DE 1,0]; p < 0,001). Los resultados fueron peores, entre las G del tercer trimestre (p = 0,031, p = 0,003 y p < 0,001, respectivamente). Conclusiones: La presentación clínica atípica de la AA durante el embarazo dificulta su diagnóstico, lo que podría traducirse en una mayor incidencia de AA complicada, infección del sitio quirúrgico y tiempo de estancia hospitalaria, sobre todo si se presenta la AA durante el tercer trimestre de gestación


Objective: To analyze the clinical presentation, management, and outcome of acute appendicitis (AA) in pregnant and nonpregnant women of childbearing age. Methods: Descriptive study of 2 cohorts of women (pregnant -P- and nonpregnant -NP-). The women, who were matched according to risk factors, were included when they underwent an emergency appendectomy based on clinical suspicion of AA. We recorded age, medical history, clinical presentation, management, and outcome. Pregnant women were classified according to gestational age of the fetus (trimester). Results: We included 153 women (51 P, 102 NP). The mean (SD) age was 28.8 (6.5) years (P women, 29.7 [5.8] years; NP, 28.3 [6.8]; P=.242). The mean Alvarado score was 7.1 (1.6) (P, 6.7 [1.7]; NP, 7.3 [1.5]; P=.016). The rate of complicated AA was higher in P (19.6%) than NP (2.9%) women (P<.001). Pregnancy was also associated with higher rates of surgical wound infection (P, 14.0%; NP, 3.0%; P=.016) and a longer mean hospital stay (P, 5.1 [4.8] days; NP, 1.7 [1.0]; P<.001). In the third trimester of P, poorer outcomes were recorded in relation to these risks (P=.031; P=.003, and P<.001, respectively). Conclusions: The atypical clinical presentation of AA during pregnancy makes diagnosis difficult and may lead to a higher incidence of complicated AA and surgical wound infection as well as longer hospital stays, particularly when AA presents in the third trimester


Asunto(s)
Humanos , Femenino , Embarazo , Adulto , Apendicitis/complicaciones , Apendicitis/diagnóstico , Apendicitis/cirugía , Complicaciones del Embarazo/diagnóstico , Complicaciones del Embarazo/cirugía , Enfermedad Aguda , Tiempo de Internación/estadística & datos numéricos , Análisis por Apareamiento , Estudios Retrospectivos , Factores de Riesgo , Infección de la Herida Quirúrgica/etiología , Resultado del Tratamiento
12.
Rev. esp. enferm. dig ; 109(6): 406-413, jun. 2017. tab, graf
Artículo en Español | IBECS (España) | ID: ibc-163248

RESUMEN

Introducción: el síndrome linfoproliferativo postrasplante (SLPT) es una complicación infrecuente que ensombrece el pronóstico de los pacientes sometidos a un trasplante hepático (TH). Su patogenia es multifactorial, siendo sus dos principales factores de riesgo la inmunodepresión y la infección del virus de Epstein- Barr (VEB); sin embargo, en actualidad se piensa que puede estar relacionada con otros factores. Métodos: estudio observacional en el que hemos analizado de forma retrospectiva 851 casos que fueron sometidos a un trasplante hepático, de los cuales diez casos han desarrollado un SLPT. Se han analizado sus características clinicopatológicas y el tratamiento recibido. Resultados: la incidencia del SLPT ha sido del 1,2% (10/851) y el tiempo medio de presentación desde el TH hasta el diagnóstico, de 36 meses (rango 1,2-144 meses). El lugar de presentación ha sido extranodal en todos los casos, siendo más frecuente la localización intestinal. Siete casos presentaron un SLPT monomorfo, todos ellos linfomas diferenciados de células B. El 50% de la serie presentó seronegatividad para el virus de Epstein-Barr. La supervivencia global ha sido del 50%. Entre estos pacientes, hemos observado tres casos de curación completa, un caso de estabilización de la enfermedad y otro caso de recurrencia. Conclusión: el SLPT es una complicación infrecuente que supone una amenaza para la vida del paciente. Para poder instaurar un diagnóstico precoz y un tratamiento que pueda modificar el curso de la enfermedad, es fundamental la identificación de los pacientes en riesgo (AU)


Introduction: Post-transplant lymphoproliferative syndrome (PTLD) is a rare and potentially life-threatening complication after liver transplantation. The aim of this study was to analyze the clinicopathologic features related to PTLD in a single institution after liver transplantation. Methods: Observational study where we have retrospectively analyzed 851 cases who underwent liver transplantation. Ten cases have developed PTLD. Their clinical-pathological characteristics and the treatment received have been analyzed. Results: PTLD incidence was 1.2% (10/851). The mean time from liver transplantation to PTLD diagnosis was 36 months (range 1.2 to 144 months). PTLD localization was extranodal in all cases, the most frequent location being intestinal. Seven cases showed a monomorphic lymphoma which in all cases was differentiated B cell lymphomas. Fifty per cent of the series were seropositive for Epstein-Barr virus. Five patients were alive at the time of the review. Among these patients, we observed three cases of complete remission and two cases of disease stabilization. The death rate was higher in the first year after diagnosis of PTLD. Conclusion: PTLD is a rare complication after liver transplantation, but it may pose a threat to the life of a liver transplant recipient. It is essential to identify patients at risk, to establish an early diagnosis and treatment that can change the outcome of the disease (AU)


Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Trastornos Linfoproliferativos/complicaciones , Trasplante de Hígado/métodos , Rituximab/uso terapéutico , Estudios Observacionales como Asunto , Complicaciones Posoperatorias/fisiopatología , Diagnóstico Precoz , Análisis Multivariante , Pronóstico , Supervivencia/fisiología , 28599 , Terapia de Inmunosupresión/métodos , Estimación de Kaplan-Meier , Factores de Riesgo , Inhibidores de la Calcineurina/uso terapéutico
14.
Rev. esp. enferm. dig ; 107(7): 417-422, jul. 2015. tab, ilus
Artículo en Español | IBECS (España) | ID: ibc-137618

RESUMEN

INTRODUCCIÓN: las variantes anatómicas de la arteria hepática pueden tener importantes implicaciones en la cirugía oncológica del páncreas. Nuestro objetivo es comparar los resultados tras un procedimiento de Whipple en pacientes con y sin presencia de una arteria hepática variante procedente de la arteria mesentérica superior. MATERIAL Y MÉTODOS: estudio analítico observacional retrospectivo en el que hemos analizado 151 pacientes con patología tumoral periampular sometidos a una duodenopancreatectomía desde enero de 2005 hasta febrero de 2012. Diferenciamos entre 2 grupos: grupo A (variante de la arteria hepática) y grupo B (no evidencia de variante de la arteria hepática). Hemos expresado los resultados como la media ± desviación estándar para las variables continuas y porcentajes para las cualitativas. Los test estadísticos fueron considerados significativos si la p < 0,05. RESULTADOS: hemos detectado 11 pacientes con anomalías de la arteria hepática (7,3%). La variante más frecuentemente fue la arteria hepática derecha aberrante (n = 7), seguida de la arteria hepática derecha accesoria (n = 2) y tronco de la arteria hepática común procedente de la arteria mesentérica superior (n = 2). En el 73% de los casos la detección de la variante arterial fue intraoperatoria. En todos los pacientes se realizó una resección R0. No se han apreciado diferencias significativas en los márgenes de resección tumoral, complicaciones, ni en la supervivencia. CONCLUSIÓN: la cirugía oncológica de la región céfalopancreática en presencia de una variante de la artería hepática es factible. La complejidad que supone tener una variante anatómica de la arteria hepática no parece influir en los márgenes de resección tumoral, complicaciones o supervivencia


INTRODUCTION: The anatomical variants of the hepatic artery may have important implications for pancreatic cancer surgery. The aim of our study is to compare the outcome following a pancreatoduodenectomy (PD) in patients with or without a variant hepatic artery arising from superior mesenteric artery. MATERIAL AND METHODS: We reviewed 151 patients with periampullary tumoral pathology. All patients underwent oncological PD between January 2005 and February 2012. Our series was divided into two groups: Group A: Patients with a hepatic artery arising from superior mesenteric artery; and Group B: Patients without a hepatic artery arising from superior mesenteric artery. We expressed the results as mean +/- standard deviation for continuous variables and percentages for qualitative variables. Statistical tests were considered significant if p < 0.05. RESULTS: We identified 11 patients with a hepatic artery arising from superior mesenteric artery (7.3%). The most frequent variant was an aberrant right hepatic artery (n = 7), following by the accessory right hepatic artery (n = 2) and the common hepatic artery trunk arising from the superior mesenteric artery (n = 2). In 73% of cases the diagnosis of the variant was intraoperative. R0 resection was performed in all patients with a hepatic artery arising from superior mesenteric artery. There were no significant differences in the tumor resection margins and the incidence of postoperative complications. CONCLUSION: Oncological PD is feasible by the presence of a hepatic artery arising from superior mesenteric artery. The complexity of having it does not seem to influence in tumor resection margins, complications and survival


Asunto(s)
Femenino , Humanos , Masculino , Pancreaticoduodenectomía/métodos , Pancreaticoduodenectomía/tendencias , Pancreaticoduodenectomía , Neoplasias Pancreáticas/patología , Neoplasias Pancreáticas/cirugía , Complicaciones Posoperatorias/clasificación , Complicaciones Posoperatorias/prevención & control , Arteria Hepática/patología , Arteria Hepática/cirugía , Arteria Hepática , Estudios Retrospectivos
15.
Cir. Esp. (Ed. impr.) ; 93(8): 530-535, oct. 2015. ilus, tab
Artículo en Español | IBECS (España) | ID: ibc-143311

RESUMEN

INTRODUCCIÓN: La ecografía endoanal dinámica (EEAD) en 3 dimensiones ha surgido en los últimos años como una alternativa a las pruebas existentes en el diagnóstico de las alteraciones del suelo pélvico. El objetivo de este trabajo es determinar la utilidad de la ecodefecografía en el diagnóstico y evaluación de los pacientes que presentan síntomas de obstrucción defecatoria, así como mostrar los resultados obtenidos tras su implementación en una unidad de suelo pélvico. MÉTODOS: Estudio retrospectivo que analiza a 66 pacientes (61 mujeres), con una edad media de 55 años (19-83). Se realizó una EEAD y se correlacionó con los síntomas y los hallazgos exploratorios en consulta. Se realizó tanto un estudio descriptivo como inferencial, así como un índice Kappa para buscar correlación entre la exploración física y la EEAD. RESULTADOS: Los motivos de consulta fueron: síndrome de obstrucción defecatoria (SOD) 36 pacientes (54,5%), prolapso de órganos pélvicos (POP) 27 pacientes (40,9%) y SOD junto con POP 3 pacientes (4,5%). La correlación de ambos grupos indica que la EEAD diagnostica más pacientes con rectocele grado III, enteroceles y anismos que la combinación de exploración-manometría-proctoscopia-ecografía bidimensional (Kappa 0,26; 0,38 y 0,21; IC 95%: 0,07-1,00; 0,15-1,00 y 0,12-1,00, respectivamente) (p < 0,001). Por el contrario, la EEAD diagnostica menos descensos del periné (Kappa 0,28; IC 95% 0,12-1,00). CONCLUSIÓN: La ecografía dinámica puede tener un papel relevante como prueba complementaria en el paciente con enfermedad del suelo pélvico, ya que permite diagnosticar procesos que mediante la inspección, la exploración física y la manometría pasarían desapercibidos


INTRODUCTION: Dynamic endoanal ultrasound has emerged in recent years as a test that could replace the now existing tests in the diagnosis of pelvic floor disorders. The aim of this paper is to determine the usefulness of echodefecography in the diagnosis and evaluation of patients with symptoms of anorrectal obstruction, and show the results obtained after its implementation in a pelvic floor unit, as a complementary tool that could replace conventional defecography. METHODS: In this retrospective study we analyzed 66 patients with a mean age of 55 years (19-83), 61 women (92%). All dynamic ultrasound was performed in 3 dimensions and was correlated with symptoms and physical findings in the consultation. A descriptive and inferential study was performed to find a kappa correlation between physical examination and echodefecography. RESULTS: The reasons for consultation were: Anorrectal obstruction syndrome 36 patients (54.5%), pelvic organ prolapse 27 patients (40.9%), and anorrectal obstruction syndrome along with pelvic organ prolapse 3 patients (4.5%). The correlation of the 2 groups indicated that echodefecography diagnosed more patients with grade III rectocele, enteroceles, and anismus than the combination of scan-ultrasound-manometry-proctoscopy (Kappa 0.26, 0.38 and 0.21, 95% CI: from 0,07 to 1.00, 0.15 to 1.00 and from 0.12 to 1.00, respectively) (P<.001). Conversely, echodefecography diagnosed less perineal descense (Kappa 0.28, 95% CI: 0.12 to 1.00). CONCLUSIONS: Dynamic anal ultrasonography may have a role as a complementary test in patients with pelvic floor disorders, achieving diagnoses that would go undetected by inspection, physical examination and manometry


Asunto(s)
Humanos , Neoplasias Pélvicas , Enfermedad Inflamatoria Pélvica , Diafragma Pélvico , Ultrasonido Enfocado Transrectal de Alta Intensidad/métodos , Rectocele , Hernia , Prolapso Rectal , Defecografía/métodos , Impactación Fecal/epidemiología , Diagnóstico Diferencial
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA