[Postoperative bed header position after burr-hole drainage of chronic subdural haematoma: systematic review and meta-analysis of randomised controlled trials]. / Posicionamiento postoperatorio de la cabecera tras drenaje de hematomas subdurales crónicos por trepanación: Revisión sistemática y metaanálisis de estudios controlados aleatorizados.

INTRODUCTION: Several studies have suggested the possible influence of postoperative bed header position on the risk of symptomatic recurrences and medical complications in patients who have been intervened due chronic subdural haematomas. Nevertheless, this hypothesis has not been assessed by a meta-analysis. METHODS: All randomised controlled trials analysing symptomatic recurrence rates in patients who underwent burr-hole drainage of chronic subdural haematomas, describing postoperative bed header positioning, were included. The primary outcome was risk of recurrence and the secondary outcome were the risks of reoperation and medical complications. Results were presented as pooled relative risks, with 95% confidence intervals. RESULTS: A total of 4 controlled studies were included. Pooled relative risks were: symptomatic recurrences 0.51 ([95% CI: 0.22-1.16]; P=.11), reoperations, 1.07 ([95% CI: 0.42-2.69]; P=.89) and medical complications, 1.15 ([95% CI: 0.7-1.91]; P=.58). No statistically significant heterogeneity was found in any of the analyses. CONCLUSION: There were no differences regarding frequency of symptomatic recurrences, reoperations or medical complications in patients who were maintained in a flat position compared with those whose bed header was elevated during the postoperative course. Despite there being consistency between the results, there is a potential risk of bias; thus proscribing definitive recommendations until studies with higher methodological quality are available.

[The influence of climate on the onset of intracranial hemorrhages]. / Variaciones climáticas y hemorragias intracraneales.

BACKGROUND: there are not studies exploring the potential role of weather conditions in the incidence of intracranial hemorrhages in Latin America. METHODS: a descriptive study was carried out in an emergency room from Cartagena de Indias (Colombia). Data for all adult patients with intracranial hemorrhage and meteorological variables of the days when intracranial hemorrhages occurred were recorded and compared to with those where not a single case. RESULTS: the differences between the average temperature, maximum and minimum temperatures, barometric pressure, relative humidity and wind speed were non statistically significant. However, when comparing the temperature differences day of the event over the previous days, those met the pre-established criteria of statistical significance. Furthermore, differences in barometric pressure, relative humidity, maximum and minimum temperature over the previous day, also reached this criterion. CONCLUSIONS: the results of this study suggest the existence of a climatic profile associated with the onset of intracranial hemorrhages.

[Brain stem compression preceded by trigeminal neuralgia in a patient with vertebro-basilar and bilateral carotid dolichoectasia]. / Compresión tronco-encefálica precedida por neuralgia del trigémino en un paciente con dolicoectasia vertebro-basilar y carotidea bilateral.

We described a patient who had left trigeminal neuralgia by vertebro-basilar dolichoectasia, who underwent microvascular decompression separating the basilar artery of the trigeminal nerve by interposing a vascular graft piece. Symptoms resolved completely after surgery. Nine years later, he has a recurrence of facial pain associated with rapidly progressive brainstem compressive symptoms. The brain MRI showed the vertebro-basilar dolichoectasia exerting compression on the ventral-lateral aspect of the pons and the medulla. In cerebral angiography confirmed the presence of dilated tortuous vertebral arteries, basilar, and of both internal carotid. To our knowledge this is the first case of brain stem compression syndrome preceded by NT in patients with vertebro-basilar dolichoectasia and one of the few cases with coexistence of vertebro-basilar and bilateral carotid dolichoectasia.

[Intracerebral hemorrhages following drainage of chronic subdural hematomas]. / Hemorragia intracerebral posterior a drenado de hematomas subdurales crónicos.

BACKGROUND: postoperative intracerebral hemorrhage after drainage of chronic subdural hematoma is a rarely reported complication; however, its incidence, according to different series may be underestimated. CASE REPORT: this report presents a 77 year old male patient who, after the drainage of bilateral chronic subdural hematomas, developed an extensive hemorrhage in the thalami, basal ganglia, midbrain and pons, with extension into the ventricles and obstructive hydrocephalus. CONCLUSIONS: compression by extra-axial collection decreases cerebral blood flow on the affected hemisphere and alters its vascular self-adjustment. The rapid increase in cerebral blood flow in brain areas with altered vascular self-adjustment appears to be the precipitating mechanism of intracerebral hemorrhage after surgical evacuation of chronic subdural hematomas.

Síndrome del muñeco cabeza de resorte por quiste aracnoideo selar en un adulto / Bobble-head doll syndrome by selar arachnoid cyst in an adult

El síndrome del muñeco cabeza de resorte es un raro trastorno usualmente descrito en la población pediátrica como resultado de lesiones selares y del tercer ventrículo, especialmente quistes coloides. Su fisiopatología no está bien esclarecida. Se ha planteado que los trastornos del funcionamiento de las aferencias y eferencias hacia el núcleo dorso-medial del tálamo originarían los movimientos y estos permanecerían en el tiempo gracias a fenómenos de aprendizaje. Presentamos un raro caso del síndrome del muñeco cabeza de resorte de una paciente adulta como consecuencia de un quiste aracnoideo selar con extensión paraselar a través de la fisura de Silvio. Se realizaron comunicaciones del quiste hacia las cisternas adyacentes con lo cual se logro control completo de los síntomas tras 48 horas del procedimiento.

Bobble head doll syndrome is a rare disorder usually described in the pediatric population as a result of sellar lesions and the third ventricle, especially colloid cysts. Its pathophysiology is not well understood. It has been suggested that functional disorders of the afferent and efferent system to the dorso-medial nucleus of the thalamus causes of the movement and these remain over time through learning phenomena. We present a rare case of bobble head doll syndrome in an adult patient caused by a sellar arachnoid cyst with parasellar extension through the Sylvian fissure. Communications were made from the cyst into adjacent cisterns thereby achieving complete control of symptoms after 48 hours of the procedure.

Apoplejía postoperatoria de un macroadenoma hipofisiario residual e infarto de la arteria cerebral media / Post-operative apoplexy of a residual pituitary macro-adenoma and middle cerebral artery infarction

La apoplejía postoperatoria de los adenomas hipofisiarios es una complicación rara vez reportada. La presión ejercida por el tumor residular edematoso puede comprometer estructuras nerviosas y vasculares adyacentes a la región selar. Describios el caso de un hombre de 69 años de edad con un tumor selar gigante a quien le fue realizada una resección incompleta a través de un acceso pterional. La cirugía fue detenida por inestabilidad hemodinámica. Cuarenta y ocho horas más tarde, desarrolla oftalmparesias y disminución bilateral de la agudeza visual, deterioro del estado de consciencia, poliuria y hemiparesia izquierda. Una tomografía cerebral simple de emergencia demostró incremento del volumen tumoral con hemorragia y un infarto en el territorio de la arteria cerebral media derecha. El paciente falleció siete días más tarde. Este caso ejemplifica esta rara y catastrófica complicación con alta morbilidad y mortalidad. En la revisión de la literatura, solo fueron encontrados dos casos de ictus isquémico debido a la compresión de arterias intracraneales mayores por apoplejía postoperatoria de macroadenomas residuales.

Postoperative apoplexy of residual pituitary adenomas is a rarely reported complication. Pressure from edematous residual tumor may affect vascular and nervous structures adjacent to sellar region. We described a 69 years old man with a giant sellar tumor who underwent to incomplete resection through pterional approach. Surgery was stopped by hemodynamic instability. Forty-eight hours later, he developed bilateral decreased of visual acuity, bilateral ophthalmoparesis, drowsiness, polyuria and left hemiparesis. An emergency computed tomography scan showed increase in tumor volume with hemorrhage and an infarct of right middle cerebral artery. The patient died seven days later. This case exemplifies this rare and catastrophic complication with high morbidity and mortality. On literature review, only two cases of ischemic strokes due to compression major intracranial arteries by postoperative tumor apoplexy were found.

Potencial terapéutico de las células madre en la enfermedad cerebrovascular: [revisión] / Therapeutic potential of stem cells in cerebrovascular disease: [review]

La enfermedad cerebrovascular es una importante causa de muerte e incapacidad en todo el mundo. Esta enfermedad es consecuencia de un complejo grupo de procesos fisiopatológicos que afectan la vasculatura del sistema nervioso, resultando en isquemia y modificaciones del metabolismo neuronal. Se ha demostrado que células neurales han ayudado a reparar los daños asociados a la enfermedad cerebrovascular en modelos animales y han conducido a mejoras en su capacidad física. Además, se ha observado que la aplicación endógena de células madre ocasiona neurogénesis espontánea en respuesta a la lesión isquémica y se puede mejorar a través de una adecuada infusión de citoquinas. En esta revisión se analizan diversos aspectos de la potencial aplicación de las células madre como estrategia terapéutica en el manejo de la enfermedad cerebrovascular...

Cerebrovascular disease is a major cause of death and disability in the worldwide, this disease results from a complex set of pathophysiologic processes that affect the nervous system vasculature, resulting in ischemia and changes in neuronal metabolism. It has been shown that neural cells helped repair damage associated with cerebrovascular disease in animal models and have led to improvements in physical capacity. Furthermore, it appears that the application of endogenous stem cells causes spontaneous neurogenesis in response to ischemic injury and can be improved through proper infusion of cytokines. This review discusses various aspects of the potential application of stem cells as a therapeutic strategy in the management of cerebrovascular disease...

Enfoque neuroquirurgico del infarto maligno de la arteria cerebral media: [revisión] / Neurosurgical focus of malignant stroke of the medium cerebral artery: [review]

El manejo quirúrgico de la enfermedad vascular cerebral (EVC) isquémica constituye un reto para el neurocirujano, esta entidad es la segunda causa más frecuente de muerte a nivel mundial precedida solo por las diferentes formas de enfermedad cardíaca isquémica. Con las actuales medidas de prevención implementadas en países desarrollados, su frecuencia como enfermedad fatal ha decrecido, de tal modo que se ubica como la tercera causa de muerte, al ser superada, además, por las neoplasias malignas. Una estrategia para el manejo de la enfermedad isquemica cerebral es la craniectomia descompresiva para casos seleccionados. Presentamos algunos topicos interesantes desde la perspectiva neuroquirurgica para el manejo de la Enfermedad Vascular Cerebral.

Posicionamiento postoperatorio de la cabecera tras drenaje de hematomas subdurales crónicos por trepanación: Revisión sistemática y metaanálisis de estudios controlados aleatorizados / Postoperative bed header position after burr-hole drainage of chronic subdural haematoma: Systematic review and meta-analysis of randomised controlled trials

INTRODUCCIÓN: Algunos estudios han señalado la posible influencia del posicionamiento postoperatorio de la cabecera sobre el riesgo de recurrencias y complicaciones médicas en los pacientes intervenidos por hematomas subdurales crónicos; sin embargo, esta hipótesis aún no se ha evaluado mediante un metaanálisis. MÉTODOS: Se incluyeron todos los estudios prospectivos controlados aleatorizados que analizaron la frecuencia de recurrencias sintomáticas en los pacientes operados por hematomas subdurales crónicos mediante trepanación, con relación al posicionamiento postoperatorio de la cabecera. El desenlace primario fueron las recurrencias sintomáticas y los secundarios, las reintervenciones y las complicaciones médicas postoperatorias. Los resultados se presentaron en riesgos relativos combinados, con sus intervalos de confianza del 95%. RESULTADOS: Fueron incluidos un total de 4 estudios controlados aleatorizados. Los riesgos relativos combinados fueron: recurrencias sintomáticas, 0,51 ([IC 95%: 0,22-1,16]; p = 0,11); reintervenciones, 1,07 ([IC 95%: 0,42-2,69]; p = 0,89) y complicaciones, 1,15 ([IC 95%: 0,7-1,91]; p = 0,58). No se encontró heterogeneidad estadísticamente significativa en ninguno de los análisis. CONCLUSIÓN: No se encontraron diferencias en el riesgo de recurrencias sintomáticas, reintervenciones ni complicaciones médicas en los pacientes que fueron mantenidos con la cabecera plana, en comparación con aquellos en quienes fue elevada en el postoperatorio. Aunque los resultados fueron consistentes entre los estudios incluidos, existe un potencial riesgo de sesgos, lo que proscribe emitir recomendaciones definitivas antes de contarse con estudios de mayor calidad metodológica

INTRODUCTION: Several studies have suggested the possible influence of postoperative bed header position on the risk of symptomatic recurrences and medical complications in patients who have been intervened due chronic subdural haematomas. Nevertheless, this hypothesis has not been assessed by a meta-analysis. METHODS: All randomised controlled trials analysing symptomatic recurrence rates in patients who underwent burr-hole drainage of chronic subdural haematomas, describing postoperative bed header positioning, were included. The primary outcome was risk of recurrence and the secondary outcome were the risks of reoperation and medical complications. Results were presented as pooled relative risks, with 95% confidence intervals. RESULTS: A total of 4 controlled studies were included. Pooled relative risks were: symptomatic recurrences 0.51 ([95% CI: 0.22-1.16]; P = .11), reoperations, 1.07 ([95% CI: 0.42-2.69]; P = .89) and medical complications, 1.15 ([95% CI: 0.7-1.91]; P = .58). No statistically significant heterogeneity was found in any of the analyses. CONCLUSION: There were no differences regarding frequency of symptomatic recurrences, reoperations or medical complications in patients who were maintained in a flat position compared with those whose bed header was elevated during the postoperative course. Despite there being consistency between the results, there is a potential risk of bias; thus proscribing definitive recommendations until studies with higher methodological quality are available

Carcinoma folicular de tiroides y metástasis a cráneo: presentación de caso / Follicular carcinoma of thyroid and skull metastases: a case report

El carcinoma folicular de tiroides muy raras veces produce metástasis a cráneo. Presentamos el caso de un hombre con masa en región parietal de varios años de evolución, la cual después de ser tratada quirúrgicamente fue diagnósticada histopatológicamente como carcinoma folicular de tiroides. Lo que nos deja como enseñanza que ante una lesión lítica en cráneo debemos buscar un foco primario en la tiroides.