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3.
Cir Esp ; 93(3): 174-80, 2015 Mar.
Artículo en Inglés, Español | MEDLINE | ID: mdl-25443154

RESUMEN

INTRODUCTION: Complete resection with clear margins in locally advanced pelvic visceral tumors, primary or recurrent, occasionally requires total pelvic exenteration (TPE). METHODS: We reviewed the results of EFA in 34 consecutive patients operated on between June 2006 and December 2013. RESULTS: Median age was 62 (40-82) years; 24 (70%) were male. The tumor origin most frequent was advanced primary rectal tumor (APRT), with 19 cases (55.9%) and most common type of exenteration was supraelevator (61.8%). R0 resection was achieved in 24 (70.6%) patients and in 16 (85%) of the APRT. Fifteen (79%) patients had pT4 APRT, and 4 (20%) pN +. Reconstruction of the bowel and bladder was performed with two stomas in 17 cases (50%), colorectal anastomosis and Bricker in 11 (32.3%) and wet double barreled colostomy in 6 (17.6%). There was no postoperative mortality; 23 (67,5%) patients had complications, and 5 (14.6%) required a postoperative reoperation to solve them. Median follow-up was 23 (13-45) months. Overall survival (OS) and disease free survival (DFS) at 2 years were 67% and 58% respectively, and the median OS and DFS was 59 months (95% CI 26-110) and 39 months (95% CI 14-64), respectively. The DFS of R0 was significantly better (p=0.003) than R1. CONCLUSIONS: TPE is a potentially curative procedure for advanced pelvic visceral malignancies with similar morbi-mortality than other extended excisional surgery.


Asunto(s)
Recurrencia Local de Neoplasia/cirugía , Exenteración Pélvica , Neoplasias Pélvicas/cirugía , Adulto , Anciano , Anciano de 80 o más Años , Supervivencia sin Enfermedad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Recurrencia Local de Neoplasia/mortalidad , Neoplasias Pélvicas/mortalidad , Estudios Retrospectivos , Tasa de Supervivencia
4.
Cir Esp ; 89(5): 269-74, 2011 May.
Artículo en Español | MEDLINE | ID: mdl-21429480

RESUMEN

A literature review has been made on the pelvic recurrence of rectal cancer using the MedLine, Ovid, EMBASE, Cochrane and Cinahl data bases. Assessment of the locoregional recurrence must be made using imaging tests in order to rule out the presence of metastasis, as well as for locating its exact location within the pelvis. As the only curative treatment should be complete resection of the recurrence with negative margins, a pre-operative CT, NMR, endorectal ultrasound and PET-CT must be performed to determine its resectability. For a potential cure, radical resections must be made, with the technique varying according to whether the location is central (axial), posterior (presacral) or lateral, as well as treatment directed at the primary tumour. Neoadjuvant treatments, brachiterapy and intra-operative radiotherapy improve the local control results and survival in these patients.


Asunto(s)
Recurrencia Local de Neoplasia/cirugía , Neoplasias del Recto/cirugía , Humanos
7.
Cir. Esp. (Ed. impr.) ; 93(3): 174-180, mar. 2015. ilus, tab
Artículo en Español | IBECS (España) | ID: ibc-133732

RESUMEN

INTRODUCCIÓN: La resección completa con márgenes libres en los tumores viscerales pélvicos localmente avanzados, primarios o recurrentes, requiere ocasionalmente de una exenteración pélvica total (EPT). MÉTODOS: Revisamos los resultados obtenidos con la EPT en 34 pacientes consecutivos operados entre junio de 2006 y diciembre de 2013. RESULTADOS: La mediana de edad fue de 62 (40-82) años; 24 (70%) eran varones. El origen tumoral más frecuente fue el avanzado y primitivo de recto (TAPR), con 19 casos (55,9%) y el tipo de exenteración, la supraelevadora (61,8%). Se logró una resección R0 en 24 (70,6%) pacientes y en 16 (85%) de los TAPR. Quince (79%) pacientes con TAPR tenían pT4, y 4 (20%) pN+. La continuidad intestinal y urinaria se realizó con 2 estomas en 17 casos (50%), Bricker y anastomosis colorrectal en 11 (32,3%) y colostomía húmeda double barreled en 6 (17,6%). No hubo mortalidad postoperatoria; 23 (67,5%) pacientes tuvieron complicaciones y 5 (14,6%) requirieron una reoperación en el postoperatorio. La mediana de seguimiento fue de 23 (13-45) meses. La supervivencia global (SG) y libre de enfermedad (SLE) a los 2 años fueron del 67% y 58% respectivamente, y la mediana de SG y SLE fue de 59 meses (IC 95%: 26 a 110) y de 39 meses (IC 95%: 14 a 64), respectivamente. La SLE de las R0 fue significativamente mejor (p = 0,003) que las R1. CONCLUSIONES: La EPT es un procedimiento potencialmente curativo para las neoplasias viscerales avanzadas de la pelvis, con una morbimortalidad similar a otras cirugías exeréticas mayores


INTRODUCTION: Complete resection with clear margins in locally advanced pelvic visceral tumors, primary or recurrent, occasionally requires total pelvic exenteration (TPE). METHODS: We reviewed the results of EFA in 34 consecutive patients operated on between June 2006 and December 2013.ResultsMedian age was 62 (40-82) years; 24 (70%) were male. The tumor origin most frequent was advanced primary rectal tumor (APRT), with 19 cases (55.9%) and most common type of exenteration was supraelevator (61.8%). R0 resection was achieved in 24 (70.6%) patients and in 16 (85%) of the APRT. Fifteen (79%) patients had pT4 APRT, and 4 (20%) pN +. Reconstruction of the bowel and bladder was performed with two stomas in 17 cases (50%), colorectal anastomosis and Bricker in 11 (32.3%) and wet double barreled colostomy in 6 (17.6%). There was no postoperative mortality; 23 (67,5%) patients had complications, and 5 (14.6%) required a postoperative reoperation to solve them. Median follow-up was 23 (13-45) months. Overall survival (OS) and disease free survival (DFS) at 2 years were 67% and 58% respectively, and the median OS and DFS was 59 months (95% CI 26-110) and 39 months (95% CI 14-64), respectively. The DFS of R0 was significantly better (p = 0.003) than R1. CONCLUSIONS: TPE is a potentially curative procedure for advanced pelvic visceral malignancies with similar morbi-mortality than other extended excisional surgery


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Exenteración Pélvica/métodos , Neoplasias Pélvicas/cirugía , Neoplasias del Recto/cirugía , Neoplasias Urogenitales/cirugía , Recurrencia Local de Neoplasia/cirugía
8.
Cir. Esp. (Ed. impr.) ; 89(5): 269-274, mayo 2011. ilus
Artículo en Español | IBECS (España) | ID: ibc-92687

RESUMEN

Se ha realizado una revisión literaria relativa a la cirugía de la recurrencia pélvica del cáncer de recto utilizando las bases de datos MedLine, Ovid, EMBASE, Cochrane y Cinahl. La evaluación por pruebas de imagen de la recidiva locorregional debe realizarse tanto para descartar la presencia de metástasis como con el objetivo de localizar el sitio preciso (subsitio) de la misma dentro de la pelvis. Como el único tratamiento curativo será la resección completa de la recidiva con márgenes negativos, se deben realizar preoperatoriamente TC, RMN, ecografía endorrectal y PET-TC para determinar la resecabilidad. Para una potencial curación, se deben realizar resecciones radicales, variando la técnica según la localización de la recurrencia sea central (axial), posterior (presacra) o lateral, así como el tratamiento efectuado del tumor primario. Los tratamientos neoadyuvantes, la braquiterapia y la RTIO mejoran los resultados de control local y la supervivencia en estos pacientes (AU)


A literature review has been made on the pelvic recurrence of rectal cancer using the MedLine, Ovid, EMBASE, Cochrane and Cinahl data bases. Assessment of the locoregional recurrence must be made using imaging tests in order to rule out the presence of metastasis, as well as for locating its exact location within the pelvis. As the only curative treatment should be complete resection of the recurrence with negative margins, a pre-operative CT,NMR, endorectal ultrasound and PET-CT must be performed to determine its resectability. For a potential cure, radical resections must be made, with the technique varying according to whether the location is central (axial), posterior (presacral) or lateral, as well as treatment directed at the primary tumour. Neoadjuvant treatments, brachiterapy and intra-operative radiotherapy improve the local control results and survival in these patients (AU)


Asunto(s)
Humanos , Recurrencia Local de Neoplasia/cirugía , Neoplasias del Recto/cirugía
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