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1.
J Clin Nurs ; 32(17-18): 6415-6426, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-36823713

RESUMEN

AIMS AND OBJECTIVES: Identify and compare learning needs, levels of self-efficacy and their association among inpatients and outpatients of a cardiac care unit with coronary heart disease who have undergone percutaneous coronary intervention (PCI) in a Swiss university hospital. BACKGROUND: After primary PCI, 42% of patients will suffer a recurrent ischemic cardiovascular event. Although adherence to therapeutic regimen contributes to prevent recurrence, patient adherence remains low. To strengthen it, learning needs and self-efficacy must be considered when developing effective therapeutic patient education (TPE). METHODS: Learning needs and self-efficacy were assessed using the Cardiac Patient Learning Needs Inventory (CPLNI) and the Cardiac Self-Efficacy Scale among inpatients and outpatients. The STROBE checklist for cross-sectional studies was used in reporting this study. RESULTS: Ninety-three patients participated in the study with a participation rate of 73.9%. The CPLNI median total score was significantly higher in inpatients than in outpatients: 4.23 (3.82, 4.64) versus 3.67 (3.33, 4.09), p < .001. In both units, participants declared that the most important need was related to 'anatomy and physiology' of the heart. Despite the high score, the least important need was about 'physical activity' for inpatients and 'miscellaneous information' for outpatients. No statistically significant differences were found among patients from both units regarding their self-efficacy level. CONCLUSIONS: This study shows that after PCI, patients have high learning needs and moderate levels of self-efficacy that require addressing. RELEVANCE TO CLINICAL PRACTICE: Patient's individual learning needs and self-efficacy level must be assessed prior/after PCI. A tailored TPE that considers individual learning needs and self-efficacy is recommended as a preventative measure to reduce recurrent ischemic cardiovascular events. Nurses can play a key role in this process. NO PATIENT OR PUBLIC CONTRIBUTION: For feasibility reasons, patients and public were not involved in the design, conduct, reporting or dissemination plans of this research.


Asunto(s)
Intervención Coronaria Percutánea , Humanos , Estudios Transversales , Autoeficacia , Puente de Arteria Coronaria , Aprendizaje
2.
Pacing Clin Electrophysiol ; 44(2): 341-359, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-33283883

RESUMEN

Anatomical-based approaches, targeting either pulmonary vein isolation (PVI) or additional extra PV regions, represent the most commonly used ablation treatments in symptomatic patients with atrial fibrillation (AF) recurrences despite antiarrhythmic drug therapy. PVI remains the main anatomical target during catheter-based AF ablation, with the aid of new technological advances as contact force monitoring to increase safety and effective radiofrequency (RF) lesions. Nowadays, cryoballoon ablation has also achieved the same level of scientific evidence in patients with paroxysmal AF undergoing PVI. In parallel, electrical isolation of extra PV targets has progressively increased, which is associated with a steady increase in complex cases undergoing ablation. Several atrial regions as the left atrial posterior wall, the vein of Marshall, the left atrial appendage, or the coronary sinus have been described in different series as locations potentially involved in AF initiation and maintenance. Targeting these regions may be challenging using conventional point-by-point RF delivery, which has opened new opportunities for coadjuvant alternatives as balloon ablation or selective ethanol injection. Although more extensive ablation may increase intraprocedural AF termination and freedom from arrhythmias during the follow-up, some of the targets to achieve such outcomes are not exempt of potential severe complications. Here, we review and discuss current anatomical approaches and the main ablation technologies to target atrial regions associated with AF initiation and maintenance.


Asunto(s)
Fibrilación Atrial/cirugía , Ablación por Catéter/métodos , Venas Pulmonares/cirugía , Procedimientos Quirúrgicos Cardíacos/métodos , Humanos , Resultado del Tratamiento
3.
J Cardiovasc Electrophysiol ; 30(12): 2657-2667, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31544291

RESUMEN

BACKGROUND: When pacing trains with a constant cycle length (CL) but increasing number of beats are introduced during a macroreentrant atrial tachycardia (MAT), the postpacing interval (PPI) is expected to increase if entrainment does not occur but could be stable if entrainment occurs. We tested the ability of PPI analysis to detect entrainment. METHODS: Synchronized pacing trains with increasing number of beats (1-20) were delivered from the coronary sinus (CS) and lateral right atrium (RA) at a CL 20 ms shorter than the MAT CL. Pacing trains were grouped in pairs differing by one-paced beat, and the ∆PPI measured. RESULTS: In an initial prospective cohort of 21 patients (48% had left atrial flutter) the mean ∆PPI was 21.3 ± 5.6 ms for pairs of pacing trains in which neither entrained the MAT and 2.8 ± 1.4 ms for those in which both entrained the MAT (P < .0001). Results were similar for common vs atypical flutter, PPI-TCL ≤30 ms vs PPI-TCL >30 ms, presence vs absence of antiarrhythmic drugs and faster vs slower MAT. When an index pacing train was compared to one with two-paced beats less, a PPI difference of <19 ms identified entrainment with 95% sensitivity and 98% specificity. In a validation cohort of 16 patients, this cut-off value resulted in sensitivity and specificity of 90% and 94%. CONCLUSIONS: A relatively constant ∆PPI in response to overdrive pacing with identical CL but different number of beats allows accurate discrimination between trains that entrained vs those which did not entrain a MAT.


Asunto(s)
Potenciales de Acción , Aleteo Atrial/diagnóstico , Función Atrial , Estimulación Cardíaca Artificial , Técnicas Electrofisiológicas Cardíacas , Frecuencia Cardíaca , Taquicardia Supraventricular/diagnóstico , Anciano , Anciano de 80 o más Años , Aleteo Atrial/fisiopatología , Aleteo Atrial/cirugía , Ablación por Catéter , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Estudios Prospectivos , Taquicardia Supraventricular/fisiopatología , Taquicardia Supraventricular/cirugía , Factores de Tiempo , Resultado del Tratamiento
4.
J Cardiovasc Electrophysiol ; 27(7): 846-50, 2016 07.
Artículo en Inglés | MEDLINE | ID: mdl-27090984

RESUMEN

INTRODUCTION AND OBJECTIVES: The Sprint Fidelis defibrillator lead (Medtronic) was recalled in 2007 due to an increased risk of failure. The generator exchange (GE) procedure has been associated with the development of Fidelis lead dysfunction. The aim of this study was to compare the rate of dysfunction between Sprint Fidelis and other defibrillator leads during the first year after GE. METHODS: A multicenter retrospective study involving patients from the UMBRELLA database who underwent GE with previous normal lead function and minimum follow-up of 1 year after the procedure was performed. The incidence of lead dysfunction was determined via remote monitoring and defined as pacing impedance > 1,500 ohm, high-voltage impedance > 100 ohm, R wave sensing under 2 mV, or the presence of VT/VF episodes classified as noise. RESULTS: A total of 531 patients were included (114 Fidelis). In the first year after GE, the total incidence of lead dysfunction was 3.6%. No significant differences were found between Fidelis and the others in survival analysis (3.5% vs. 3.6%, respectively, log-rank 0.002, P = 0.962). CONCLUSIONS: According to our results, the preventive removal/replacement of the Sprint Fidelis leads with normal function until GE is not a recommended practice since the rate of dysfunction after the procedure in this subgroup is no different compared with other defibrillator leads.


Asunto(s)
Arritmias Cardíacas/terapia , Desfibriladores Implantables , Remoción de Dispositivos/efectos adversos , Cardioversión Eléctrica/instrumentación , Suministros de Energía Eléctrica , Falla de Prótesis , Anciano , Arritmias Cardíacas/diagnóstico , Arritmias Cardíacas/fisiopatología , Bases de Datos Factuales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Estudios Retrospectivos , Factores de Riesgo , España , Factores de Tiempo
5.
Pacing Clin Electrophysiol ; 39(1): 21-7, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26173070

RESUMEN

BACKGROUND: Ventricular overdrive pacing (VOP) produces reset during the transition zone (TZ) of QRS fusion in orthodromic reentrant tachycardia (ORT) and after the TZ in atrioventricular nodal reentrant tachycardia (AVNRT), and this represents a simple diagnostic maneuver to differentiate the two tachycardia mechanisms. OBJECTIVE: The purpose of this study was to determine whether the number of beats with reset in the TZ predicts accessory pathway (AP) location in ORT. METHODS: We retrospectively reviewed 57 patients with ORT (21 left-sided AP, 20 septal AP, and 16 right-sided AP) and 20 patients with AVNRT (19 typical AVNRT and one atypical AVNRT) who underwent VOP from the right ventricular apex. We analyzed the number of beats with reset during or after the TZ, demonstrated by fixed ventricular stimulus-atrial (SA) interval during VOP. RESULTS: The overall mean tachycardia cycle length [CL] minus VOP CL was 22.6 ± 7.5 ms with no statistical difference between the groups (P = 0.480). The mean number of beats in the TZ with fixed SA interval was 2.5 ± 1.4 for the whole ORT group, 1.1 ± 0.4 for left-sided AP (range 1-2), 2.8  ±  0.9 for septal AP (range 1-5), and 4.0 ± 0.9 for right-sided AP (range 3-6) (P < 0.001). Using a cutoff >2 beats distinguished right- versus left-sided AP in all cases. CONCLUSION: Assessing the number of beats in the TZ with fixed SA interval during VOP helps to determine AP location in ORT and adds valuable information to an established simple diagnostic pacing maneuver, especially when a two-catheter simplified approach is employed.


Asunto(s)
Fascículo Atrioventricular Accesorio/diagnóstico , Fascículo Atrioventricular Accesorio/terapia , Estimulación Cardíaca Artificial/métodos , Electrocardiografía/métodos , Taquicardia por Reentrada en el Nodo Atrioventricular/diagnóstico , Taquicardia por Reentrada en el Nodo Atrioventricular/terapia , Adulto , Diagnóstico por Computador/métodos , Femenino , Frecuencia Cardíaca , Ventrículos Cardíacos , Humanos , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados , Sensibilidad y Especificidad , Resultado del Tratamiento
6.
Pacing Clin Electrophysiol ; 38(9): 1066-72, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-26095973

RESUMEN

BACKGROUND: The stimulus-atrial (SA) interval minus ventriculoatrial (VA) interval (SA-VA) difference represents a simple diagnostic maneuver to distinguish between atrioventricular nodal reentrant tachycardia (AVNRT) and orthodromic reentrant tachycardia (ORT) during electrophysiology study. However, its usefulness has largely been studied in selected patient subgroups. The purpose of this study was to evaluate the performance of the SA-VA difference against commonly used diagnostic maneuvers in a large cohort of consecutive patients. METHODS: Consecutive patients with inducible supraventricular tachycardia and successful entrainment through pacing trains from right ventricular apex during an electrophysiological study were included. Atrial tachycardias were excluded. The following intervals were calculated for each patient: SA-VA difference, His potential, and atrial electrogram during entrainment minus His potential and atrial electrogram during tachycardia, and the corrected return cycle. RESULTS: A total of 456 patients fulfilled the inclusion criteria, of which electrophysiological study revealed 265 typical AVNRT, 38 atypical AVNRT, and 54 and 108 ORT through a septal and free-wall accessory pathway, respectively. An SA-VA difference >99 ms identified AVNRT in all patients with sensitivity, specificity, and positive and negative predictive values of 97.7%, 96.9%, 98.3%, and 95.7%, respectively. CONCLUSIONS: This study confirms the high ability to distinguish AVNRT from ORT using the SA-VA difference, not only in selected patient subgroups, but as whole when a cut-off of >99 ms is used.


Asunto(s)
Fascículo Atrioventricular Accesorio/diagnóstico , Técnicas Electrofisiológicas Cardíacas/métodos , Taquicardia por Reentrada en el Nodo Atrioventricular/diagnóstico , Taquicardia Reciprocante/diagnóstico , Adulto , Estudios de Cohortes , Femenino , Humanos , Masculino , Persona de Mediana Edad , Reproducibilidad de los Resultados , Sensibilidad y Especificidad
7.
Europace ; 16(4): 558-62, 2014 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24058180

RESUMEN

AIMS: A new remote catheter system (AMIGO™ Remote Catheter System) compatible with conventional ablation catheters is now commercially available but no data about its performance in clinical use during ablation have been reported. This study evaluates the feasibility, efficacy, and safety of cavo-tricuspid isthmus (CTI) ablation with this system in patients with typical atrial flutter (AFl). METHODS AND RESULTS: Sixty patients with typical AFl underwent CTI ablation using the new remote catheter navigation system with 8 mm tip or irrigated catheters in three centres following each centre's routine practice. The endpoint was stable bidirectional CTI block. CTI ablation was successful in 98% of patients. Ablation was completed manually in one patient. The overall procedure, fluoroscopy, and radiofrequency times (median ± standard deviation, range) were 123 ± 42 (50-250), 24 ± 13 (3-82), and 10 ± 8 (1.17-43.3) min, respectively. Three patients had vascular complications not requiring surgical intervention. There were no complications related to the remote catheter manipulation system. CONCLUSION: Cavo-tricuspid isthmus ablation for typical AFl can be safely and effectively performed with the AMIGO™. The learning curve seems to be short even for physicians with limited ablation experience.


Asunto(s)
Aleteo Atrial/cirugía , Catéteres Cardíacos , Ablación por Catéter/instrumentación , Robótica/instrumentación , Cirugía Asistida por Computador/instrumentación , Válvula Tricúspide/cirugía , Vena Cava Inferior/cirugía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Aleteo Atrial/diagnóstico , Aleteo Atrial/fisiopatología , Ablación por Catéter/efectos adversos , Competencia Clínica , Diseño de Equipo , Estudios de Factibilidad , Femenino , Humanos , Curva de Aprendizaje , Masculino , Persona de Mediana Edad , Tempo Operativo , Estudios Prospectivos , España , Cirugía Asistida por Computador/efectos adversos , Factores de Tiempo , Resultado del Tratamiento , Válvula Tricúspide/fisiopatología , Vena Cava Inferior/fisiopatología , Adulto Joven
8.
Heart Rhythm ; 20(6): 822-830, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-37245897

RESUMEN

BACKGROUND: Pharmacological options for rate control in atrial fibrillation are scarce. Ivabradine was postulated to reduce the ventricular rate in this setting. OBJECTIVES: The objectives of this study were to evaluate the mechanism of inhibition of atrioventricular conduction produced by ivabradine and to determine its efficacy and safety in atrial fibrillation. METHODS: The effects of ivabradine on atrioventricular node and ventricular cells were studied by in vitro whole-cell patch-clamp experiments and mathematical simulation of human action potentials. In parallel, a multicenter, randomized, open-label, phase III clinical trial compared ivabradine with digoxin for uncontrolled permanent atrial fibrillation despite ß-blocker or calcium channel blocker treatment. RESULTS: Ivabradine 1 µM inhibited "funny" current and rapidly activating delayed rectifier potassium channel current by 28.9% and 22.8%, respectively (P < .05). The sodium channel current and L-type calcium channel current were reduced only at 10 µM. Ivabradine slowed the firing frequency of a modeled human atrioventricular node action potential by 10.6% and induced a minimal prolongation of ventricular action potential. Thirty-five (51.5%) patients were randomized to ivabradine and 33 (49.5%) to digoxin. The mean daytime heart rate decreased by 11.6 beats/min (-11.5%) in the ivabradine arm (P = .02) vs 19.6 (-20.6%) in the digoxin arm (P < .001), although the noninferiority margin of efficacy was not met (Z = -1.95; P = .97). The primary safety end point occurred in 3 patients (8.6%) on ivabradine and in 8 (24.2%) on digoxin (P = .10). CONCLUSION: Ivabradine produced a moderate rate reduction in patients with permanent atrial fibrillation. The inhibition of funny current in the atrioventricular node seems to be the main mechanism responsible for this reduction. Compared with digoxin, ivabradine was less effective, was better tolerated, and had a similar rate of serious adverse events.


Asunto(s)
Fibrilación Atrial , Humanos , Ivabradina/uso terapéutico , Fibrilación Atrial/tratamiento farmacológico , Frecuencia Cardíaca/fisiología , Digoxina/uso terapéutico , Antagonistas Adrenérgicos beta/uso terapéutico
9.
Invest Clin ; 53(3): 262-72, 2012 Sep.
Artículo en Español | MEDLINE | ID: mdl-23248970

RESUMEN

The aim of this study was to evaluate the fracture resistance of teeth with incomplete root development and intracanal reinforcement with adhesives materials. 50 human central and lateral incisors were instrumented and prepared to simulate an immature tooth and filled apically with MTA. The samples were divided into four experimental groups and one control group. Group 1: resin composite Filtek P90; Group 2: glass Ionomer Vitremer; Group 3: resin composite Filtek Z350 XT; Group 4: glass Ionomer Ketac N 100; Group 5: negative control (instrumented but not reinforced). After, the fracture test was performed using a fracture universal testing machine (Instron). The maximum values of resistance before catastrophic fracture were collected and analyzed by Anova (p = 0.05). The results show a significant difference between the groups compared (p = 0.02). A significant difference was found between group 1 (847.73 N) and group 5 (474.77 N) (p = 0.02) applying the Bonferroni test. Despite the limitations of the study, the conclusion is that micro-hybrid composite resins are ideal materials to strengthen teeth with incomplete root development endodontically treated.


Asunto(s)
Cementos Dentales , Análisis del Estrés Dental , Tratamiento del Conducto Radicular/métodos , Raíz del Diente/crecimiento & desarrollo , Humanos , Técnicas In Vitro , Ensayo de Materiales , Fracturas de los Dientes
10.
Artículo en Inglés | MEDLINE | ID: mdl-36361111

RESUMEN

During the COVID-19 pandemic, nurses were exposed to many stressors, which may have been associated with some mental health problems. However, most of the studies carried out on nurses' quality of life and workplace wellbeing during the COVID-19 pandemic took a pathogenic approach. Given that current scientific knowledge in this field presented too many gaps to properly inform preventive and therapeutic action, the aim of this study was to explore whether protective factors (resilience, perceived social support, and professional identification) and stressors (perceived stress and psychosocial risks in the workplace) influenced the quality of life and workplace wellbeing perceived by Portuguese nurses during the COVID-19 pandemic. Data for this cross-sectional study was collected through online self-administered questionnaires. Linear regression models were used to analyze the relationships between variables. Results showed that perceived stress, resilience and job satisfaction were associated with quality of life and workplace wellbeing among Portuguese nurses. The study's findings could serve to inform health policy and should draw the attention of nursing managers to the needs and difficulties reported by nurses, to the importance of providing them with emotional support, and to the relevance of promoting a good work environment.


Asunto(s)
COVID-19 , Enfermeras y Enfermeros , Humanos , COVID-19/epidemiología , Lugar de Trabajo/psicología , Pandemias , Calidad de Vida , Estudios Transversales , Factores Protectores , Portugal/epidemiología , Satisfacción en el Trabajo , Encuestas y Cuestionarios
11.
Food Chem ; 393: 133292, 2022 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-35688092

RESUMEN

There is a lack of knowledge about the influence of seasonality on the microbial and physicochemical quality of oysters in Sado and Mira rivers. Water, sediment, and oysters (Crassostrea angulata and Crassostrea gigas) were collected for microbiological, nutritional, and sensory analyses. The microbiological water quality and the oyster shell contamination were better during the warmer months. No seasonal effect was observed on sediments and on oyster meat. A good physicochemical and nutritional quality was also observed, with high content of polyunsaturated fatty acids, including omega-3 fatty acids, resulting in good lipid quality indices. From the sensory evaluation, both oysters' species were well scored and presented the highest scores (4) in parameters such as cream-ivory colour, sea smell, firmness and juiciness. These attributes denote the freshness degree at the time of the tasting, reflecting the quality of the bivalve.


Asunto(s)
Crassostrea , Calidad de los Alimentos , Estaciones del Año , Animales , Crassostrea/química , Crassostrea/microbiología , Ríos
12.
Sci Total Environ ; 806(Pt 3): 151232, 2022 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-34715209

RESUMEN

Diclofenac is a pharmaceutical active compound frequently detected in wastewater and water bodies, and often reported to be persistent and difficult to biodegrade. While many previous studies have focussed on assessing diclofenac biodegradation in nitrification and denitrification processes, this study focusses on diclofenac biodegradation in the enhanced biological phosphorus removal (EBPR) process, where the efficiency of this process for diclofenac biodegradation as well as the metabolites generated are not well understood. An enrichment of Accumulibacter polyphosphate accumulating organisms (PAOs) was operated in an SBR for over 300 d, and acclimatized to 20 µg/L of diclofenac, which is in a similar range to that observed in domestic wastewater influents. The diclofenac biotransformation was monitored in four periods of stable operation and linked to the microbial community and metabolic behaviour in each period. Nitrification was observed in two of the four periods despite the addition of a nitrification inhibitor, and these periods were positively correlated with increased diclofenac biodegradation. Interestingly, in two periods with excellent phosphorus removal (>99%) and no nitrification, different levels of diclofenac biotransformation were observed. Period 2, enriched in Accumulibacter Type II achieved more significant diclofenac biotransformation (3.4 µg/gX), while period 4, enriched in Accumulibacter Type I achieved lower diclofenac biotransformation (0.4 µg/gX). In total, 23 transformation products were identified, with lower toxicity than the parent compound, enabling the elucidation of multiple metabolic pathways for diclofenac biotransformation. This study showed that PAOs can contribute to diclofenac biotransformation, yielding less toxic transformation products, and can complement the biodegradation carried out by other organisms in activated sludge, particularly nitrifiers.


Asunto(s)
Diclofenaco , Fósforo , Reactores Biológicos , Biotransformación , Aguas del Alcantarillado
13.
Plants (Basel) ; 11(13)2022 Jun 30.
Artículo en Inglés | MEDLINE | ID: mdl-35807691

RESUMEN

This study describes the antimicrobial and anti-inflammatory effects from extracts obtained from the leaves of Salvia lavanduloides. The plant material was macerated with three solvents of ascending polarity (n-hexane (Sl-Hex), ethyl acetate (Sl-AcOEt), and dichloromethane (Sl-D)). The extracts, fractions (SlD-2 and SlD-3), and isolated compounds (15,16-epoxy-10-ß-hydroxy-neo-cleroda-3,7,13(16),14-tetraene-17,12R:18,19-diolide (1), salviandulin A (2), and eupatorin (3)) were evaluated as antimicrobials against Gram-negative, Gram-positive bacteria and the fungus Candida albicans (Ca) using the minimum inhibitory concentration (MIC) and the anti-inflammatory activity induced by 13-acetate of 12-O-tetradecanoylforbol (TPA). Sl-D and Sl-AcOEt extracts, SlD-2 and SlD-3 fractions showed the highest antimicrobial activity. The isolated compounds showed good activity against Pseudomonas aeruginosa with a MIC < 2 µg/mL, while the anti-inflammatory activity, the Sl-Hex, Sl-D extracts, and SlD-3 fraction presented an inhibition of 62, 45 and 61%, respectively, while (2) 70% and (3) 72%.

14.
Eur Cardiol ; 16: e21, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-34093742

RESUMEN

Catheter ablation remains the most effective and relatively minimally invasive therapy for rhythm control in patients with AF. Ablation has consistently shown a reduction of arrhythmia-related symptoms and significant improvement in patients' quality of life compared with medical treatment. The ablation strategy relies on a well-established anatomical approach of effective pulmonary vein isolation. Additional anatomical targets have been reported with the aim of increasing procedure success in complex substrates. However, larger ablated areas with uncertainty of targeting relevant regions for AF initiation or maintenance are not exempt from the potential risk of complications and pro-arrhythmia. Recent developments in mapping tools and computational methods for advanced signal processing during AF have reported novel strategies to identify atrial regions associated with AF maintenance. These novel tools - although mainly limited to research series - represent a significant step forward towards the understanding of complex patterns of propagation during AF and the potential achievement of patient-tailored AF ablation strategies for the near future.

15.
J Int Acad Periodontol ; 22(4): 231-235, 2020 10 01.
Artículo en Inglés | MEDLINE | ID: mdl-32980835

RESUMEN

AIMS: This study evaluated the mechanical properties of mandibular bone tissue retrieved from postmenopausal women under alendronate treatment. METHODS: Twenty postmenopausal women were divided into two groups: healthy postmenopausal subjects (control group) and osteoporotic subjects treated with alendronate (alendronate group). Mandibular bone samples were retrieved with a trephine bur at the time of dental implant placement and fixed in 4% formalin. Samples were processed for hard tissue histology, and the bone surface was analyzed for nanohardness measurement. Nanohardness and elastic modulus were evaluated by using a Berkovich tip with elastic modulus of 1.016x106 MPa, Poisson coefficient of 0.3, and a load of 100 mN. Each cycle was configured with a load time of 18 seconds (speed of 1 mN/second), the discharge time of 18 seconds, and a rest time of 5 seconds during indentation at a depth of 10 µm. RESULTS: The control group presented the highest values for nanohardness and elastic modulus (p less than 0.05) in relation to the osteoporotic subjects. CONCLUSIONS: Within the limitations of the study, it can be concluded that treatment with alendronate negatively influenced the mechanical properties of mandibular bone in postmenopausal women by reducing bone nanohardness and elastic modulus.


Asunto(s)
Alendronato , Posmenopausia , Módulo de Elasticidad , Femenino , Dureza , Humanos , Mandíbula
16.
Toxicon ; 170: 94-98, 2019 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-31563524

RESUMEN

The present study analyzes cases of scorpionism in 11 dogs and a cat that were registered at a veterinary clinic in the city of Manizales, between 2009 and 2018. All eight cases where expert identification of the arthropod was possible, involved Centruroides gracilis (Latreille, 1804). None of the stings were lethal, though two cases were classified as severe envenomation and five moderate. The primary sign was local pain, in addition to lameness in all 10 cases that involved one of the limbs (83,3%, 10 of 12 cases). The other two cases had injuries involving the face. The established treatment was symptomatic with clinical and patient monitoring. Antivenom could not be used due to its high cost and scarcity. However, even the severest cases improved satisfactorily, and all patients were discharged without complication.


Asunto(s)
Enfermedades de los Gatos/etiología , Enfermedades de los Perros/etiología , Picaduras de Escorpión/veterinaria , Animales , Enfermedades de los Gatos/diagnóstico , Enfermedades de los Gatos/terapia , Gatos , Colombia , Enfermedades de los Perros/diagnóstico , Enfermedades de los Perros/terapia , Perros , Cojera Animal/etiología , Dolor/tratamiento farmacológico , Dolor/etiología , Dolor/veterinaria , Estudios Retrospectivos , Picaduras de Escorpión/diagnóstico , Picaduras de Escorpión/terapia , Escorpiones
19.
Rev. cuba. estomatol ; 59(2): e3402, abr.-jun. 2022. graf
Artículo en Español | LILACS, CUMED | ID: biblio-1408395

RESUMEN

Introducción: La regeneración ósea permite la reintegración y conformación de tejidos posteriores a la extracción o corrección de un defecto óseo. Es considerada una técnica de estimulación para la formación de hueso nuevo, donde se favorece la construcción y la preservación del coágulo con el fin de evitar la infiltración en la zona de reparación, de componentes celulares (células epiteliales y conjuntivas). Objetivos: Describir los cambios a nivel morfológico durante el proceso de regeneración ósea y mencionar distintas técnicas de preservación ósea y los factores necesarios para su realización. Presentación de caso: Paciente femenina con periodontitis apical asintomática en órganos dentarios 34 y 37, que se sometió a preservación alveolar mediante la práctica de exodoncia atraumática y regeneración ósea con xenoinjerto, colocación de membrana colágeno e implante posextractivo inmediato. Principales comentarios: La colocación inmediata de implantes posexodoncia permite una buena preservación del alveolo, siempre y cuando las condiciones clínicas del paciente así lo permitan, por ejemplo, la ausencia de procesos infecciosos agudizados como en el presente caso. La regeneración ósea, en el defecto producido por el proceso inflamatorio periapical, implicó una correcta detoxificación de la zona a través del curetaje y la aplicación de antibióticos. La respuesta inmunológica exagerada ante injertos óseos no es frecuente; sin embargo, en este caso llevó a una pérdida parcial del sustituto óseo sin comprometer el pronóstico de los implantes(AU)


Introduction: Bone regeneration allows the reintegration and conformation of tissues after the extraction or correction of a bone defect. It is considered a stimulation technique for the formation of new bone, where the construction and preservation of the clot is favored in order to avoid infiltration in the repair area of cellular components (epithelial and conjunctiva cells). Objective: Describe the changes at the morphological level during the bone regeneration process and mention different bone preservation techniques and the necessary factors for their implementation. Case presentation: Female patient with asymptomatic apical periodontitis in dental organs 34 and 37, who underwent alveolar preservation through the practice of atraumatic exodontics and bone regeneration with xenograft, collagen membrane placement and immediate post-extraction implant. Main comments: The immediate placement of post-exodontic implants allows a good preservation of the alveolus, as long as the clinical conditions of the patient allow it, for example, the absence of exacerbated infectious processes as in the present case. Bone regeneration, in the defect produced by the periapical inflammatory process, involved a correct detoxification of the area through curettage and the application of antibiotics. Exaggerated immune response to bone grafts is not common; however, in this case it led to a partial loss of bone substitute without compromising the prognosis of the implants(AU)


Asunto(s)
Humanos , Femenino , Persona de Mediana Edad , Periodontitis Periapical/etiología , Cirugía Bucal/métodos , Regeneración Ósea , Xenoinjertos , Antibacterianos/uso terapéutico
20.
Rev. senol. patol. mamar. (Ed. impr.) ; 35(2): 94-99, Abril - Junio 2022.
Artículo en Español | IBECS (España) | ID: ibc-230661

RESUMEN

Introducción: Los médicos de familia juegan un papel fundamental en la promoción de las prácticas adecuadas de la lactancia materna (LM), por lo que deben tener un conocimiento adecuado sobre el tema.ObjetivoEvaluar el conocimiento sobre la LM y los factores asociados en los médicos de familia en una unidad de primer nivel de atención de Cuernavaca, México.Material y métodosSe realizó un estudio transversal, en 93 médicos adscritos y residentes de medicina de familia. El conocimiento sobre la LM se evaluó mediante el cuestionario ECoLa de 20 ítems, considerando variables familiares y demográficas. Se realizó una estadística descriptiva de los datos y los factores asociados al nivel de conocimiento se evaluaron mediante un modelo de regresión logística.ResultadosDe la muestra, el 72% fueron mujeres; 41% estaban casados y 55% tenían al menos un hijo, el 23% había tomado al menos un curso de LM. Se obtuvo una media de 11,5 aciertos en el cuestionario ECoLa, 52% se clasificaron en un nivel de conocimiento bajo, 45% en regular y 3% en adecuado. Después del ajuste por edad, cursos de lactancia y estado civil, las principales variables asociadas a un conocimiento regular/bueno fueron tener al menos un hijo (OR 4,63 IC 95% 1,1-19,42) y el sexo (mujer OR 5,75 IC 95% 1,58-20,94).ConclusionesEl 52% de los médicos de familia mostró un conocimiento bajo sobre la LM. La experiencia personal de la paternidad o maternidad de los médicos de familia se asocia al mejor conocimiento de la LM, superando a las capacitaciones y a los cursos. (AU)


Introduction: The Family doctors play a fundamental role in promoting an adequate breastfeeding practices, so they must have an adequate knowledge of this matters.ObjectiveEvaluate the knowledge about breastfeeding in family doctors of a first level care unit in Cuernavaca, Mexico.Material and methodsThe study was cross-sectional with 93 Family doctors and family medicine residents. The knowledge about breastfeeding was evaluated using the ECoLa questionnaire of 20 items, considering family and demographic variables. Were performed descriptive statistics and the factors associated with the level of knowledge were evaluated using a logistic regression model.ResultsFrom the sample 72% were women, 41% were married and 55% had at least one child, 23% had taken at least one breastfeeding course. On average 11.5 hits out in ECoLa questionnaire, 52% were classified as low knowledge level, 45% as regular and 3% as good. After adjustment for age, lactation courses, and marital status. The main variables associate to knowledge regular / good were had at least one child, (OR 4.63 95% CI 1.1-19.42), and sex (woman OR 5.75 95% CI 1.58-20.94).Conclusions52% of family doctors showed low knowledge about breastfeeding. The personal experience of paternity or maternity of family doctors is a relevant factor associated with better knowledge of exclusive breastfeeding, surpassing training and courses. (AU)


Asunto(s)
Humanos , Lactancia Materna/métodos , Medicina Familiar y Comunitaria , Responsabilidad Parental , Paternidad , Estudios Transversales , Encuestas y Cuestionarios
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