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1.
Kinetics of interferon-λ and receptor expression in response to in vitro respiratory viral infection.
Acta Virol
; 67(1): 99-108, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36950890
2.
Hybrid Proteins with Short Conformational Epitopes of the Receptor-Binding Domain of SARS-CoV-2 Spike Protein Promote Production of Virus-Neutralizing Antibodies When Used for Immunization.
Biochemistry (Mosc)
; 87(4): 319-330, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35527370
3.
Structural and Immunoreactivity Properties of the SARS-CoV-2 Spike Protein upon the Development of an Inactivated Vaccine.
Viruses
; 15(2)2023 02 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36851694
4.
VH3-53/66-Class RBD-Specific Human Monoclonal Antibody iB20 Displays Cross-Neutralizing Activity against Emerging SARS-CoV-2 Lineages.
J Pers Med
; 12(6)2022 May 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35743680
5.
Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1.
Mol Cell Biochem
; 347(1-2): 79-87, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20941529
6.
5,6-Dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 19(2): 451-8, 2009 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19054673
7.
5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 19(21): 6047-52, 2009 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19796938
8.
Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 19(22): 6404-12, 2009 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19818610
9.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: exploration of 7'-substitution of benzothiadiazine.
Bioorg Med Chem Lett
; 18(4): 1413-8, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18242088
10.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents.
Bioorg Med Chem Lett
; 18(4): 1419-24, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18226901
11.
Hexahydro-pyrrolo- and hexahydro-1H-pyrido[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 18(18): 5002-5, 2008 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18722768
12.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents.
Bioorg Med Chem Lett
; 18(20): 5635-9, 2008 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18796353
13.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda6-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties.
Bioorg Med Chem Lett
; 18(11): 3421-6, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18442904
14.
Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 18(12): 3616-21, 2008 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18487044
15.
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7'-substituents and initial pharmacokinetic assessments.
Bioorg Med Chem Lett
; 18(11): 3446-55, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18457949
16.
Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 18(14): 4181-5, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18554907
17.
4-(1,1-Dioxo-1,4-dihydro-1lambda6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 18(16): 4628-32, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18662878
18.
Cellular transformation of the investigational new anticancer drug NB1011, a phosphoramidate of 5-(2-bromovinyl)-2'-deoxyuridine, results in modification of cellular proteins not DNA.
Biochem Pharmacol
; 65(5): 823-31, 2003 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12628478
19.
An inactivated, adjuvanted whole virion clade 2.2 H5N1 (A/Chicken/Astana/6/05) influenza vaccine is safe and immunogenic in a single dose in humans.
Clin Vaccine Immunol
; 20(8): 1314-9, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23803900
20.
Kinetic properties of human thymidylate synthase, an anticancer drug target.
Biochem Biophys Res Commun
; 307(2): 297-300, 2003 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-12859954
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