A Fusion-Assisted Multi-Stream Deep Learning and ESO-Controlled Newton-Raphson-Based Feature Selection Approach for Human Gait Recognition.

The performance of human gait recognition (HGR) is affected by the partial obstruction of the human body caused by the limited field of view in video surveillance. The traditional method required the bounding box to recognize human gait in the video sequences accurately; however, it is a challenging and time-consuming approach. Due to important applications, such as biometrics and video surveillance, HGR has improved performance over the last half-decade. Based on the literature, the challenging covariant factors that degrade gait recognition performance include walking while wearing a coat or carrying a bag. This paper proposed a new two-stream deep learning framework for human gait recognition. The first step proposed a contrast enhancement technique based on the local and global filters information fusion. The high-boost operation is finally applied to highlight the human region in a video frame. Data augmentation is performed in the second step to increase the dimension of the preprocessed dataset (CASIA-B). In the third step, two pre-trained deep learning models-MobilenetV2 and ShuffleNet-are fine-tuned and trained on the augmented dataset using deep transfer learning. Features are extracted from the global average pooling layer instead of the fully connected layer. In the fourth step, extracted features of both streams are fused using a serial-based approach and further refined in the fifth step by using an improved equilibrium state optimization-controlled Newton-Raphson (ESOcNR) selection method. The selected features are finally classified using machine learning algorithms for the final classification accuracy. The experimental process was conducted on 8 angles of the CASIA-B dataset and obtained an accuracy of 97.3, 98.6, 97.7, 96.5, 92.9, 93.7, 94.7, and 91.2%, respectively. Comparisons were conducted with state-of-the-art (SOTA) techniques, and showed improved accuracy and reduced computational time.

Splice site recognition - deciphering Exon-Intron transitions for genetic insights using Enhanced integrated Block-Level gated LSTM model.

Bioinformatics is a contemporary interdisciplinary area focused on analyzing the growing number of genome sequences. Gene variants are differences in DNA sequences among individuals within a population. Splice site recognition is a crucial step in the process of gene expression, where the coding sequences of genes are joined together to form mature messenger RNA (mRNA). These genetic variants that disrupt genes are believed to be the primary reason for neuro-developmental disorders like ASD (Autism Spectrum Disorder) is a neuro-developmental disorder that is diagnosed in individuals, families, and society and occurs as the developmental delay in one among the hundred genes that are associated with these disorders. Missense variants, premature stop codons, or deletions alter both the quality and quantity of encoded proteins. Predicting genes within exons and introns presents main challenges, such as dealing with sequencing errors, short reads, incomplete genes, overlapping, and more. Although many traditional techniques have been utilized in creating an exon prediction system, the primary challenge lies in accurately identifying the length and spliced strand location classification of exons in conjunction with introns. From now on, the suggested approach utilizes a Deep Learning algorithm to analyze intricate and extensive genomic datasets. M-LSTM is utilized to categorize three binary combinations (EI as 1, IE as 2, and none as 3) using spliced DNA strands. The M-LSTM system is able to sequence extensive datasets, ensuring that long information can be stored without any impact on the current input or output. This enables it to recognize and address long-term connections and problems with rapidly increasing gradients. The proposed model is compared internally with Naïve Bayes and Random Forest to assess its efficacy. Additionally, the proposed model's performance is forecasted by utilizing probabilistic parameters like recall, F1-score, precision, and accuracy to assess the effectiveness of the proposed system.

Lung as a target for COVID-19: Mechanistic insights and probable candidate molecules for cure.

Novel coronavirus (SARS nCoV2), belonging to the family coronaviridae, remains a dreadful pathogen affecting the respiratory tract and lungs. COVID-19 declared a global pandemic by WHO, has become a serious cause of concern for clinicians and researchers, who need to understand the significant biology and pathogenicity of this virus to design better treatment modalities. Existing antiretroviral drugs remain partially ineffective in critical subjects with associated co-morbidities. This review provides an insight into the molecular mechanisms by which SARS-CoV2 targets the lungs leading to ARDS in severe cases. This also addresses the possible drug targets and certain anti-inflammatory natural compounds that can be looked upon as promising adjuvant therapeutics for COVID-19.

Genetic hyperparameter optimization with Modified Scalable-Neighbourhood Component Analysis for breast cancer prognostication.

Breast cancer is common among women resulting in mortality when left untreated. Early detection is vital so that suitable treatment could assist cancer from spreading further and save people's life. The traditional way of detection is a time-consuming process. With the evolvement of DM (Data Mining), the healthcare industry could be benefitted in predicting the disease as it permits the physicians to determine the significant attributes for diagnosis. Though, conventional techniques have used DM-based methods to identify breast cancer, they lacked in terms of prediction rate. Moreover, parametric-Softmax classifiers have been a general option by conventional works with fixed classes, particularly when huge labelled data are present during training. Nevertheless, this turns into an issue for open set cases where new classes are encountered along with few instances to learn a generalized parametric classifier. Thus, the present study aims to implement a non-parametric strategy by optimizing the embedding of a feature rather than parametric classifiers. This research utilizes Deep CNN (Deep Convolutional Neural Network) and Inception V3 for learning visual features which preserve neighbourhood outline in semantic space relying on NCA (Neighbourhood Component Analysis) criteria. Delimited by its bottleneck, the study proposes MS-NCA (Modified Scalable-Neighbourhood Component Analysis) that relies on a non-linear objective function to perform feature fusion by optimizing the distance-learning objective due to which it gains the capability of computing inner feature products without performing mapping which increases the scalability of MS-NCA. Finally, G-HPO (Genetic-Hyper-parameter Optimization) is proposed. In this case, the new stage in the algorithm simply denotes the enhancement in the length of chromosome bringing several hyperparameters into subsequent XGBoost, NB and RF models having numerous layers for identifying the normal and affected cases of breast cancer for which optimized hyper-parameter values of RF (Random Forest), NB (Naïve Bayes), and XGBoost (eXtreme Gradient Boosting) are determined. This process helps in improvising the classification rate which is confirmed through analytical results.

Modified Meta Heuristic BAT with ML Classifiers for Detection of Autism Spectrum Disorder.

ASD (autism spectrum disorder) is a complex developmental and neurological disorder that impacts the social life of the affected person by disturbing their capability for interaction and communication. As it is a behavioural disorder, early treatment will improve the quality of life of ASD patients. Traditional screening is carried out with behavioural assessment through trained physicians, which is expensive and time-consuming. To resolve the issue, several conventional methods strive to achieve an effective ASD identification system, but are limited by handling large data sets, accuracy, and speed. Therefore, the proposed identification system employed the MBA (modified bat) algorithm based on ANN (artificial neural networks), modified ANN (modified artificial neural networks), DT (decision tree), and KNN (k-nearest neighbours) for the classification of ASD in children and adolescents. A BA (bat algorithm) is utilised for the automatic zooming capability, which improves the system's efficacy by excellently finding the solutions in the identification system. Conversely, BA is effective in the identification, it still has certain drawbacks like speed, accuracy, and falls into local extremum. Therefore, the proposed identification system modifies the BA optimisation with random perturbation of trends and optimal orientation. The dataset utilised in the respective model is the Q-chat-10 dataset. This dataset contains data of four stages of age groups such as toddlers, children, adolescents, and adults. To analyse the quality of the dataset, dataset evaluation mechanism, such as the Chi-Squared Statistic and p-value, are used in the respective research. The evaluation signifies the relation of the dataset with respect to the proposed model. Further, the performance of the proposed detection system is examined with certain performance metrics to calculate its efficiency. The outcome revealed that the modified ANN classifier model attained an accuracy of 1.00, ensuring improved performance when compared with other state-of-the-art methods. Thus, the proposed model was intended to assist physicians and researchers in enhancing the diagnosis of ASD to improve the standard of life of ASD patients.

Automated Cognitive Health Assessment Based on Daily Life Functional Activities.

Dementia is increasing day-by-day in older adults. Many of them are spending their life joyfully due to smart home technologies. Smart homes contain several smart devices which can support living at home. Automated assessment of smart home residents is a significant aspect of smart home technology. Detecting dementia in older adults in the early stage is the basic need of this time. Existing technologies can detect dementia timely but lacks performance. In this paper, we proposed an automated cognitive health assessment approach using machines and deep learning based on daily life activities. To validate our approach, we use CASAS publicly available daily life activities dataset for experiments where residents perform their routine activities in a smart home. We use four machine learning algorithms: decision tree (DT), Naive Bayes (NB), support vector machine (SVM), and multilayer perceptron (MLP). Furthermore, we use deep neural network (DNN) for healthy and dementia classification. Experiments reveal the 96% accuracy using the MLP classifier. This study suggests using machine learning classifiers for better dementia detection, specifically for the dataset which contains real-world data.

Privacy Preserved Cervical Cancer Detection Using Convolutional Neural Networks Applied to Pap Smear Images.

Image processing has enabled faster and more accurate image classification. It has been of great benefit to the health industry. Manually examining medical images like MRI and X-rays can be very time-consuming, more prone to human error, and way more costly. One such examination is the Pap smear exam, where the cervical cells are examined in laboratory settings to distinguish healthy cervical cells from abnormal cells, thus indicating early signs of cervical cancer. In this paper, we propose a convolutional neural network- (CNN-) based cervical cell classification using the publicly available SIPaKMeD dataset having five cell categories: superficial-intermediate, parabasal, koilocytotic, metaplastic, and dyskeratotic. CNN distinguishes between healthy cervical cells, cells with precancerous abnormalities, and benign cells. Pap smear images were segmented, and a deep CNN using four convolutional layers was applied to the augmented images of cervical cells obtained from Pap smear slides. A simple yet efficient CNN is proposed that yields an accuracy of 0.9113% and can be successfully used to classify cervical cells. A simple architecture that yields a reasonably good accuracy can increase the speed of diagnosis and decrease the response time, reducing the computation cost. Future researchers can build upon this model to improve the model's accuracy to get a faster and more accurate prediction.

Empowering Foot Health: Harnessing the Adaptive Weighted Sub-Gradient Convolutional Neural Network for Diabetic Foot Ulcer Classification.

In recent times, DFU (diabetic foot ulcer) has become a universal health problem that affects many diabetes patients severely. DFU requires immediate proper treatment to avert amputation. Clinical examination of DFU is a tedious process and complex in nature. Concurrently, DL (deep learning) methodologies can show prominent outcomes in the classification of DFU because of their efficient learning capacity. Though traditional systems have tried using DL-based models to procure better performance, there is room for enhancement in accuracy. Therefore, the present study uses the AWSg-CNN (Adaptive Weighted Sub-gradient Convolutional Neural Network) method to classify DFU. A DFUC dataset is considered, and several processes are involved in the present study. Initially, the proposed method starts with pre-processing, excluding inconsistent and missing data, to enhance dataset quality and accuracy. Further, for classification, the proposed method utilizes the process of RIW (random initialization of weights) and log softmax with the ASGO (Adaptive Sub-gradient Optimizer) for effective performance. In this process, RIW efficiently learns the shift of feature space between the convolutional layers. To evade the underflow of gradients, the log softmax function is used. When logging softmax with the ASGO is used for the activation function, the gradient steps are controlled. An adaptive modification of the proximal function simplifies the learning rate significantly, and optimal proximal functions are produced. Due to such merits, the proposed method can perform better classification. The predicted results are displayed on the webpage through the HTML, CSS, and Flask frameworks. The effectiveness of the proposed system is evaluated with accuracy, recall, F1-score, and precision to confirm its effectual performance.

Cardiovascular Disease Detection using Ensemble Learning.

One of the most challenging tasks for clinicians is detecting symptoms of cardiovascular disease as earlier as possible. Many individuals worldwide die each year from cardiovascular disease. Since heart disease is a major concern, it must be dealt with timely. Multiple variables affecting health, such as excessive blood pressure, elevated cholesterol, an irregular pulse rate, and many more, make it challenging to diagnose cardiac disease. Thus, artificial intelligence can be useful in identifying and treating diseases early on. This paper proposes an ensemble-based approach that uses machine learning (ML) and deep learning (DL) models to predict a person's likelihood of developing cardiovascular disease. We employ six classification algorithms to predict cardiovascular disease. Models are trained using a publicly available dataset of cardiovascular disease cases. We use random forest (RF) to extract important cardiovascular disease features. The experiment results demonstrate that the ML ensemble model achieves the best disease prediction accuracy of 88.70%.

Falling and Drowning Detection Framework Using Smartphone Sensors.

Advancements in health monitoring using smartphone sensor technologies have made it possible to quantify the functional performance and deviations in an individual's routine. Falling and drowning are significant unnatural causes of silent accidental deaths, which require an ambient approach to be detected. This paper presents the novel ambient assistive framework Falling and Drowning Detection (FaDD) for falling and drowning detection. FaDD perceives input from smartphone sensors, such as accelerometer, gyroscope, magnetometer, and GPS, that provide accurate readings of the movement of an individual's body. FaDD hierarchically recognizes the falling and drowning actions by applying the machine learning model. The approach activates embedding, in a smartphone application, to notify emergency alerts to various stakeholders (i.e., guardian, rescue, and close circle community) about drowning of an individual. FaDD detects falling, drowning, and routine actions with good accuracy of 98%. Furthermore, the FaDD framework enhances coordination to provide more efficient and reliable healthcare services to people.

An efficient approach for textual data classification using deep learning.

Text categorization is an effective activity that can be accomplished using a variety of classification algorithms. In machine learning, the classifier is built by learning the features of categories from a set of preset training data. Similarly, deep learning offers enormous benefits for text classification since they execute highly accurately with lower-level engineering and processing. This paper employs machine and deep learning techniques to classify textual data. Textual data contains much useless information that must be pre-processed. We clean the data, impute missing values, and eliminate the repeated columns. Next, we employ machine learning algorithms: logistic regression, random forest, K-nearest neighbors (KNN), and deep learning algorithms: long short-term memory (LSTM), artificial neural network (ANN), and gated recurrent unit (GRU) for classification. Results reveal that LSTM achieves 92% accuracy outperforming all other model and baseline studies.

Ensemble deep learning for brain tumor detection.

With the quick evolution of medical technology, the era of big data in medicine is quickly approaching. The analysis and mining of these data significantly influence the prediction, monitoring, diagnosis, and treatment of tumor disorders. Since it has a wide range of traits, a low survival rate, and an aggressive nature, brain tumor is regarded as the deadliest and most devastating disease. Misdiagnosed brain tumors lead to inadequate medical treatment, reducing the patient's life chances. Brain tumor detection is highly challenging due to the capacity to distinguish between aberrant and normal tissues. Effective therapy and long-term survival are made possible for the patient by a correct diagnosis. Despite extensive research, there are still certain limitations in detecting brain tumors because of the unusual distribution pattern of the lesions. Finding a region with a small number of lesions can be difficult because small areas tend to look healthy. It directly reduces the classification accuracy, and extracting and choosing informative features is challenging. A significant role is played by automatically classifying early-stage brain tumors utilizing deep and machine learning approaches. This paper proposes a hybrid deep learning model Convolutional Neural Network-Long Short Term Memory (CNN-LSTM) for classifying and predicting brain tumors through Magnetic Resonance Images (MRI). We experiment on an MRI brain image dataset. First, the data is preprocessed efficiently, and then, the Convolutional Neural Network (CNN) is applied to extract the significant features from images. The proposed model predicts the brain tumor with a significant classification accuracy of 99.1%, a precision of 98.8%, recall of 98.9%, and F1-measure of 99.0%.