Analysis on short-term change of macular function and the correlates after intravitreal conbercept for CRVO-ME.

AIM: To study the short-term change of macular function and the correlates after intravitreal conbercept for CRVO-ME. STUDY DESIGN: Prospective, clinical study. METHODS: Twenty Three patients(23 eyes) were recruited, who were non-ischemia central retinal vein occlusion diagnosed by FFA (fundus fluorescein angiography) and treated with intravitreal conbercept for macular edema, best - corrected visual acuity ( BCVA), central macular thickness(CMT), amplitude density of P1 wave and implicit time of P1,N1 wave from ring 1 and ring 2 of mf-ERG were measured before and 1 week、2 month after treatment. RESULTS: Compared to the baseline, BCVA、CMT、amplitude density of P1 wave and implicit time of P1,N1 wave from ring 1 and ring 2 were greatly improved at 1 W、2 M after treatment; better results were gained at 2 M compared to 1 W; Pearson correlation analysis shows no significantly correlation between the improvement of mf-ERG with the change of BCVA、CMT. CONCLUSION: The BCVA、the structure and the function of macular were greatly improved after intravitreal conbercept for central retinal vein occlusion induced macular edema; however no significantly correlation between the improvement of the function of macular with the strcture of macular and BCVA.

[Suitable summer habitat of the khulan in the Mt. Kalamaili Ungulate Nature Reserve and estimation of its population]. / 新疆卡拉麦里山有蹄类野生动物自然保护区夏季蒙古野驴适宜生境与种群数量评估.

The khulan (Equus hemionus hemionus) is a representative species in desert, semi-desert and desert steppe in Asia. The estimation of suitable habitat and population density of khulan can provide scientific decision-making basis for the conservation management. We investigated the distribution and population density of khulan in the Mt. Kalamaili Ungulate Nature Reserve in Xinjiang during May-August in 2018 and 2019, using the line transect method. The khulan population density, number and the encounter rate were estimated by the Distance 7.0 software, and through the MaxEnt model analysis and combining environmental variables, we assessed the most suitable habitats and main influencing factors. In total, we recorded 4782 individuals from 718 groups and 363 effective occurrences. Our results showed that the suitable summer habitat covered an area of 6737.5 km2, accounting for 45.4% of the total reserve area and located mainly in the central and eas-tern parts of the reserve. We estimated that the density of the summer khulan population was (0.5±0.1) individuals·km-2 and the total khulan population were (3246±575) individuals in the Mt. Kalamaili Ungulate Nature Reserve. The prediction accuracy of MaxEnt model was relatively high, with an average AUC of 0.890. The results of the Jackknife test showed that the distance to water sources, vegetation type, distance to human interference, distance to national highway G216, altitude, and precipitation of driest areas were the most important factors affecting the habitat suitability for khulan. For improving the protection of the khulan population in this reserve, we suggested strengthen the protection of water sources, adjust the core areas, monitor wildlife passages, and enhance traffic construction.