Detalles de la búsqueda
1.
Development of 1,5-diarylpyrazoles as EGFR/JNK-2 dual inhibitors: design, synthesis, moleecular docking, and bioactivity evaluation.
Bioorg Med Chem Lett
; 102: 129673, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38408511
2.
Discovery of oxindole-based FLT3 inhibitors as a promising therapeutic lead for acute myeloid leukemia carrying the oncogenic ITD mutation.
Arch Pharm (Weinheim)
; 356(2): e2200407, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36403191
3.
Controlled microwave-assisted reactions: A facile synthesis of polyfunctionally substituted phthalazines as dual EGFR and PI3K inhibitors in CNS SNB-75 cell line.
Bioorg Chem
; 122: 105740, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35298961
4.
Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities.
Mol Divers
; 26(3): 1743-1759, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-34455532
5.
A Novel Curcumin Arginine Salt: A Solution for Poor Solubility and Potential Anticancer Activities.
Molecules
; 28(1)2022 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615455
6.
New nicotinic acid-based 3,5-diphenylpyrazoles: design, synthesis and antihyperlipidemic activity with potential NPC1L1 inhibitory activity.
Mol Divers
; 25(2): 673-686, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-32067133
7.
Densely functionalized cinnolines: Controlled microwave-assisted facile one-pot multi-component synthesis and in vitro anticancer activity via apoptosis induction.
Bioorg Chem
; 101: 103932, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32506019
8.
New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity.
Bioorg Chem
; 82: 360-377, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30428415
9.
New 1,3,4-oxadiazole/oxime hybrids: Design, synthesis, anti-inflammatory, COX inhibitory activities and ulcerogenic liability.
Bioorg Chem
; 74: 15-29, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28738249
10.
Novel 1,3,4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities.
Bioorg Chem
; 69: 48-63, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27669120
11.
Ring expansions of acyloxy nitroso compounds.
Tetrahedron Lett
; 56(43): 5870-5873, 2015 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-26663984
12.
Exploration of the Safety and Solubilization, Dissolution, Analgesic Effects of Common Basic Excipients on the NSAID Drug Ketoprofen.
Pharmaceutics
; 15(2)2023 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-36840035
13.
Studies on the Nonalkaloidal Secondary Metabolites of Hippeastrum vittatum (L'Her.) Herb. Bulbs.
ACS Omega
; 8(30): 26749-26761, 2023 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37546665
14.
Vanillin-Based Indolin-2-one Derivative Bearing a Pyridyl Moiety as a Promising Anti-Breast Cancer Agent via Anti-Estrogenic Activity.
ACS Omega
; 8(7): 6968-6981, 2023 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36844536
15.
Design, Preparation and Evaluation of Supramolecular Complexes with Curcumin for Enhanced Cytotoxicity in Breast Cancer Cell Lines.
Pharmaceutics
; 14(11)2022 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36365104
16.
Molecular hybrids: A five-year survey on structures of multiple targeted hybrids of protein kinase inhibitors for cancer therapy.
Eur J Med Chem
; 225: 113768, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34450497
17.
New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors.
Pharmaceuticals (Basel)
; 14(11)2021 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34832895
18.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs.
RSC Adv
; 10(45): 26895-26916, 2020 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35515773
19.
Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation.
Eur J Med Chem
; 146: 79-92, 2018 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29396364
20.
Nitroxyl (HNO): A Possible Strategy for Fighting Cancer.
Curr Top Med Chem
; 16(22): 2464-70, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26873191