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BACKGROUND: Published literature regarding the demographics and mechanism of injury for traumatic brain injury (TBI) in India has not been analyzed in an organized sample. OBJECTIVES: The objective of this systematic review was to organize the published literature from India related to TBI and analyze it in a very specific sample to identify the specific patterns of injury and associated mortality. MATERIALS AND METHODS: A search strategy with specific inclusion criteria was performed in PubMed, Cochrane, Web of Science, and the World Health Organisation (WHO) Global Health Library. The process included an additional search within the indexed literature and the website-based population survey reports. RESULTS: Our review identified 72 studies from 300 potentially relevant articles based on the broad criteria that defined the demographics of the patients suffering from TBI and the details of trauma sustained, including the mechanism of injury as well as its diagnosis, management, and outcome. Changes in demographic patterns, the patterns of the body regions involved, the associated injuries, the clinical presentation, the follow-up status of patients suffering from TBI, who may or may not have shown clinical improvement, the overall outcome, as well as the mortality and disability status reported in the literature were analyzed. A high incidence of TBI in the productive population is of serious concern. Extremes of ages are more vulnerable to severe injury and a poor outcome. CONCLUSION: Quantitative analysis of injuries and outcomes of TBI victims shows a bigger health impact in the economically active population and in patients in the extremes of age groups.
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Lesiones Traumáticas del Encéfalo/epidemiología , Factores de Edad , Lesiones Traumáticas del Encéfalo/diagnóstico , Lesiones Traumáticas del Encéfalo/terapia , Humanos , Incidencia , India/epidemiología , Puntaje de Gravedad del Traumatismo , PublicacionesRESUMEN
BACKGROUND: Ventriculoperitoneal shunt (VPS) surgery is the most common procedure performed for the treatment of hydrocephalus. Erosive bladder perforation by a peritoneal catheter is an extremely rare complication of VPS. Only ten cases involving the normal (non-augmented) urinary bladder have been reported so far. CASE: We report a case of erosive bladder perforation, intra-corporeal knot formation, and perurethral extrusion of the distal end of VPS. This is the second only case report so far in the world literature showing triad of uncommon VPS complications in a single patient. CONCLUSION: Prompt management could avoid further complications. Patient's parents should be aware about this rare complication, so that they can seek timely medical help.
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Falla de Prótesis , Uretra/lesiones , Vejiga Urinaria/lesiones , Derivación Ventriculoperitoneal , Niño , Humanos , Hidrocefalia/cirugía , Masculino , Uretra/cirugía , Vejiga Urinaria/cirugíaRESUMEN
Objective This study was aimed to compare comparative efficacy of transsphenoidal endonasal endoscopic and microscopic pituitary surgery at single center of a developing country. Methods This study included 198 patients in which 50 patients were studied prospectively and 148 patients were studied retrospectively, diagnosed with pituitary adenoma who presented to neurosurgery department at Sawai Man Singh hospital in Jaipur, India, and were operated via transsphenoidal route between 2013 and 2018. Patients' records were reviewed and relevant clinical and surgical data were collected. Patients were divided into two groups based on the surgical procedure performed, endoscopic endonasal transsphenoid approach (group 1) and microscopic transsphenoidal approach (group 2). Outcomes, in terms of efficacy and the resulting complications of each procedure were compared and analyzed. Results A total of 198 patients with pituitary adenoma were operated during the study period. Among them, 119 (60.1%) patients were operated by endoscopic and 79 (39.9%) patients were operated by microscopic transsphenoidal approach. In endoscopic group, intraoperative cerebrospinal fluid (CSF) leak was present in 39 patients (32.77%) and 23 (29.11%) in microscopic group. Complete tumor removal was achieved in 69.75% in endoscopic and 48.13% in microscopic group ( p = 0.004). Endocrine control was achieved in 78.94% (30 out of 38) in endoscopic and 68.18% (15 out of 22 patients) in microscopic group. Conclusion The transsphenoidal approaches for resection of pituitary adenoma, both endoscopic and microscopic approach, are minimally invasive and effective for disease control. Both the approaches lead to similar endocrine control, visual symptoms, complications, and long-term outcome. Therefore, the selection of the final approach should be individualized, ultimately depending on the surgeons' comfort, experience, and familiarity with the particular technique.
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BACKGROUND: This study was done to evaluate the effects of cranioplasty on cerebrohemodynamics (cerebral blood flow [CBF] and mean transient time [MTT]) and cerebrospinal fluid (CSF) hydrodynamics (flow velocities) by using computed tomography perfusion and cardiac-gated cine phase magnetic resonance imaging (MRI) (phase contrast [PC] MRI), respectively. It also aims to determine the co-relation between changes in CBF, MTT, and CSF flow dynamics with neurocognitive outcome. RESULTS: The mean values of ipsilateral CBF were 27.58 and 41.66 mL/min/100 g in pre- and postcranioplasty patients, respectively (P = 0.04). Contralateral CBF also showed improvement from 38.76 to 60.44 mL/min/100 g (P = 0.03). Mean values of MTT were found to be decreased in the bilateral hemisphere after cranioplasty. On evaluation of CSF flow velocities by PC MRI, the means of the maximum velocity and peak velocity at the aqueduct of Sylvius were increased from pre- to postcranioplasty as 2.36 to 3.84 cm/s (P = 0.048) and 1.21 to 3.50 cm/s (P < 0.001), respectively. Cognitive evaluation showed a significant improvement at 1 (P = 0.035) and 6 months (P = 0.002) postcranioplasty. METHODS: All cases were subjected to precranioplasty cine phase cardiac gated contrast MRI for CSF dynamics and computed tomography perfusion for cerebrovascular hemodynamic parameters. CBF and related indices were calculated at different regions of interest with the help of the manufacturer's software package of computed tomography perfusion in the ipsilateral hemisphere and simultaneously on the contralateral side. Cine cardiac gated phase contrast MRI was also done for CSF flow velocity at the aqueduct of Sylvius and median aperture (foramen of Magendie). Both studies were again performed on postcranioplasty day 5-7. CONCLUSIONS: Cranioplasty can remarkably improve cortical perfusion for both the ipsilateral and contralateral hemispheres. Postoperative increased CSF velocities suggest improved rapid turnover of CSF in a circuit and possibly play a role in good neurologic outcome. Our study shows there is improvement in CSF flow at the aqueduct of Sylvius after cranioplasty. We propose that improvement in CSF circulation along with changes in CBF co-relate well with cognitive outcome (Montreal Cognitive Assessment score).
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Lesiones Traumáticas del Encéfalo/fisiopatología , Lesiones Traumáticas del Encéfalo/psicología , Líquido Cefalorraquídeo , Cognición , Hidrodinámica , Cráneo/cirugía , Adolescente , Adulto , Volumen Sanguíneo , Lesiones Traumáticas del Encéfalo/diagnóstico por imagen , Lesiones Traumáticas del Encéfalo/cirugía , Técnicas de Imagen Sincronizada Cardíacas , Circulación Cerebrovascular , Medios de Contraste , Lateralidad Funcional , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Proyectos Piloto , Periodo Posoperatorio , Estudios Prospectivos , Resultado del TratamientoRESUMEN
BACKGROUND AND OBJECTIVE: Traumatic brain injury (TBI) is a major health issue in developing nations such as India along with underreporting of TBI data because of a lack of major studies targeting the population with TBI. Various lacunae from field to tertiary centers are responsible for this significant burden of TBIs. We studied the epidemiologic profile of 1150 patients with TBI including the predictors of the outcome of TBIs in a tertiary health care institution in North India to identify the modifiable factors that could be used to improve the outcome and reduce the TBI burden. METHODS: Patients presenting with TBI to a level I trauma center were identified and enrolled in the study. Data regarding patient information from accident to discharge or death were collected as per designed format and analyzed to determine outcome predictors. RESULTS: Mean age was 36 ± 15.8 years and 84.6% of patients were male; road traffic accident was the mode of injury in 64.26% of cases. Lack of adequate prehospital care was seen in our study. Glasgow Coma Scale score on admission, Injury Severity Score, and Rotterdam CT score were found to be the 3 statistically significant predictors of outcome in patients with TBI. CONCLUSIONS: Knowledge about the causes, pattern, and distribution of patients with TBI from this study is helpful in policy making, research, health management, and rehabilitation at the national level in ours and in other nations.
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Lesiones Traumáticas del Encéfalo/diagnóstico , Accidentes de Tránsito , Adolescente , Adulto , Lesiones Traumáticas del Encéfalo/epidemiología , Niño , Preescolar , Femenino , Escala de Coma de Glasgow , Mortalidad Hospitalaria , Humanos , India , Puntaje de Gravedad del Traumatismo , Masculino , Persona de Mediana Edad , Pronóstico , Estudios Retrospectivos , Factores de Riesgo , Factores Sexuales , Tasa de Supervivencia , Centros Traumatológicos , Adulto JovenRESUMEN
AIM: The aim of this study was to compare the efficacy of endoscopic versus microscopic excision of pituitary adenoma, and to evaluate the merits and demerits of each approach. MATERIALS AND METHODS: Prospective data were collected and patients were surgically treated for pituitary adenoma at SMS Hospital, Jaipur, Rajasthan, India. Patients consent was obtained. Age, sex, presenting symptoms, length of hospital stay, pre- and post-operative hormone status, extent of resections of tumors, and intra- and post-operative complication were noted. RESULTS: A total of thirty patients with pituitary adenoma were operated transsphenoidally. Seventeen patients were operated by endonasal endoscopic transsphenoidal surgery and 13 patients were operated by microscopic transsphenoidal surgery. In an endoscopic group, complete tumor excision was achieved in 11 (64.71%) patients, and in microscopic group, it was achieved in 6 (46.15%) patients. In endoscopic group, mean operative time was 111.29 ± 21.95 min (ranged 80-135 min), and in microscopic group, it was 134.38 ± 8.33 min (ranged 120-145 min). In endoscopic group, mean blood loss was 124.41 ± 39.64 ml (60-190 ml), and in microscopic group, it was 174.62 ± 37.99 (100-220 ml). Postoperative sinusitis was present in 1 (5.88%) patient in endoscopic group and in 2 (15.38%) patients in microscopic group. CONCLUSION: Endoscopic approach provides a wide surgical field and broad lateral vision making easier distinction of tumor tissues. Thus, there is less blood loss, greater extent of tumor removal and it had less operative time, less postoperative complication, and early discharge from the hospital.
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Craniocerebral maduromycetoma is extremely rare; only 2 cases have been reported so far. The authors report a case of maduromycetoma in a 17-year-old girl from a rural background in the state of Rajasthan, India, with involvement of the right parietal cortex, overlying bone, and subcutaneous tissue. The mass was totally excised, along with the involved dura mater, bone, and scalp. She was given antifungal drugs in the postoperative period. The patient responded very well to the treatment, and there were no signs of recurrence at the 6-month follow-up visit. The clinical features, imaging and histopathological investigations, and management of this rare entity are discussed, and the available literature is reviewed.