Detalles de la búsqueda
1.
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models.
Antimicrob Agents Chemother
; 68(3): e0139423, 2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38289076
2.
Individual Components of Polymyxin B Modeled via Population Pharmacokinetics to Design Humanized Dosage Regimens for a Bloodstream and Lung Infection Model in Immune-Competent Mice.
Antimicrob Agents Chemother
; 67(5): e0019723, 2023 05 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37022153
3.
First Penicillin-Binding Protein Occupancy Patterns for 15 ß-Lactams and ß-Lactamase Inhibitors in Mycobacterium abscessus.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33106266
4.
Comparable Efficacy and Better Safety of Double ß-Lactam Combination Therapy versus ßLactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials.
Antimicrob Agents Chemother
; 63(7)2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30988147
5.
First Penicillin-Binding Protein Occupancy Patterns of ß-Lactams and ß-Lactamase Inhibitors in Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 62(6)2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29712652
6.
miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal.
Funct Integr Genomics
; 17(2-3): 203-212, 2017 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-27541609
7.
Achieving the Promise of Therapeutic Extracellular Vesicles: The Devil is in Details of Therapeutic Loading.
Pharm Res
; 34(5): 1053-1066, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28315083
8.
Clinical Pharmacology Considerations for the "Off-the-Shelf" Allogeneic Cell Therapies.
Clin Pharmacol Ther
; 115(6): 1233-1250, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38501153
9.
Evaluation of Patient-Centric Sample Collection Technologies for Pharmacokinetic Assessment of Large and Small Molecules.
Clin Pharmacol Ther
; 2024 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38671563
10.
Risk Factors of Hyperglycemia After Treatment With the AKT Inhibitor Ipatasertib in the Prostate Cancer Setting: A Machine Learning-Based Investigation.
JCO Clin Cancer Inform
; 7: e2200168, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37116107
11.
A Phase Ib, Open-label Study Evaluating the Safety and Efficacy of Ipatasertib plus Rucaparib in Patients with Metastatic Castration-resistant Prostate Cancer.
Clin Cancer Res
; 29(17): 3292-3300, 2023 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37339186
12.
Drug-Drug Interaction Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Ipatasertib in Combination with Darolutamide in Patients with Advanced Prostate Cancer.
Pharmaceutics
; 14(10)2022 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36297536
13.
Mitigating ipatasertib-induced glucose increase through dose and meal timing modifications.
Clin Transl Sci
; 15(12): 2989-2999, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36197694
14.
Pharmacokinetics of Ipatasertib in Subjects With Hepatic Impairment Using 2 Methods of Classification of Hepatic Function.
J Clin Pharmacol
; 62(2): 171-181, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34402068
15.
Characterization of exposure-response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study.
Cancer Chemother Pharmacol
; 90(6): 511-521, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36305957
16.
Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling.
Clin Pharmacol Ther
; 109(4): 1000-1020, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33576025
17.
Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury.
Cell Death Dis
; 11(2): 138, 2020 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32080178
18.
Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five ß-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae.
mBio
; 11(1)2020 02 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32047131
19.
Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics.
Pharmaceutics
; 11(7)2019 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31295857
20.
Novel Population Pharmacokinetic Approach to Explain the Differences between Cystic Fibrosis Patients and Healthy Volunteers via Protein Binding.
Pharmaceutics
; 11(6)2019 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31216743