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1.
When special populations intersect with drug-drug interactions: Application of physiologically-based pharmacokinetic modeling in pregnant populations.
Biopharm Drug Dispos
; 42(4): 160-177, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33759451
2.
Drug Interactions for Low-Dose Inhaled Nemiralisib: A Case Study Integrating Modeling, In Vitro, and Clinical Investigations.
Drug Metab Dispos
; 48(4): 307-316, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32009006
3.
Clinical Extrapolation of the Effects of Dolutegravir and Other HIV Integrase Inhibitors on Folate Transport Pathways.
Drug Metab Dispos
; 47(8): 890-898, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31167838
4.
Estimation of the unbound brain concentration of P-glycoprotein substrates or nonsubstrates by a serial cerebrospinal fluid sampling technique in rats.
Mol Pharm
; 11(2): 477-85, 2014 Feb 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24380373
5.
Physiologically-based pharmacokinetic modeling of prominent oral contraceptive agents and applications in drug-drug interactions.
CPT Pharmacometrics Syst Pharmacol
; 13(4): 563-575, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38130003
6.
Development of a physiologically based pharmacokinetic model of fostemsavir and its pivotal application to support dosing in pregnancy.
CPT Pharmacometrics Syst Pharmacol
; 2024 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38690782
7.
Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug.
CPT Pharmacometrics Syst Pharmacol
; 12(6): 808-820, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36855819
8.
Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer.
Pharm Res
; 29(3): 770-81, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22011930
9.
Robust physiologically based pharmacokinetic model of rifampicin for predicting drug-drug interactions via P-glycoprotein induction and inhibition in the intestine, liver, and kidney.
CPT Pharmacometrics Syst Pharmacol
; 11(7): 919-933, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35570332
10.
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective.
Clin Pharmacol Ther
; 112(3): 573-592, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35612761
11.
Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions.
Curr Drug Metab
; 22(7): 523-531, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33397250
12.
Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications.
Clin Pharmacol Ther
; 109(1): 55-64, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32460379
13.
Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.
Clin Pharmacol Ther
; 107(5): 1082-1115, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31628859
14.
Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective.
Clin Pharmacol Ther
; 104(5): 916-932, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30137645
15.
Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat.
J Cent Nerv Syst Dis
; 9: 1179573517693596, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28469522
16.
Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites.
J Clin Pharmacol
; 56 Suppl 7: S23-39, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27385177
17.
Industrial Perspective on the Benefits Realized From the FDA's Model-Informed Drug Development Paired Meeting Pilot Program.
Clin Pharmacol Ther
; 110(5): 1172-1175, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33991429
18.
Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.
Clin Cancer Res
; 16(23): 5664-78, 2010 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20829328
19.
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks.
Clin Cancer Res
; 15(19): 6148-57, 2009 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19789319
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