Detalles de la búsqueda
1.
Gene-based therapeutics for rare genetic neurodevelopmental psychiatric disorders.
Mol Ther
; 30(7): 2416-2428, 2022 07 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35585789
2.
Single- and multiple-dose safety, tolerability, pharmacokinetic, and pharmacodynamic profiles of ASP0367, or bocidelpar sulfate, a novel modulator of peroxisome proliferator-activated receptor delta in healthy adults: Results from a phase 1 study.
Muscle Nerve
; 65(1): 110-120, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34642949
3.
Hepatotoxicity following administration of onasemnogene abeparvovec (AVXS-101) for the treatment of spinal muscular atrophy.
J Hepatol
; 74(3): 560-566, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33186633
4.
Evaluation of single and multiple doses of a novel mGlu2 agonist, a potential antipsychotic therapy, in healthy subjects.
Br J Clin Pharmacol
; 83(8): 1654-1667, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28156011
5.
Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human.
Int J Neuropsychopharmacol
; 18(2)2014 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-25637376
6.
Intrathecal Onasemnogene Abeparvovec for Sitting, Nonambulatory Patients with Spinal Muscular Atrophy: Phase I Ascending-Dose Study (STRONG).
J Neuromuscul Dis
; 10(3): 389-404, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36911944
7.
Onasemnogene abeparvovec for presymptomatic infants with two copies of SMN2 at risk for spinal muscular atrophy type 1: the Phase III SPR1NT trial.
Nat Med
; 28(7): 1381-1389, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35715566
8.
Onasemnogene abeparvovec for presymptomatic infants with three copies of SMN2 at risk for spinal muscular atrophy: the Phase III SPR1NT trial.
Nat Med
; 28(7): 1390-1397, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35715567
9.
N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes.
J Pharmacol Exp Ther
; 336(1): 165-77, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20947638
10.
Adeno-associated virus serotype 9 antibodies in patients screened for treatment with onasemnogene abeparvovec.
Mol Ther Methods Clin Dev
; 21: 76-82, 2021 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33768131
11.
Onasemnogene abeparvovec gene therapy for symptomatic infantile-onset spinal muscular atrophy type 1 (STR1VE-EU): an open-label, single-arm, multicentre, phase 3 trial.
Lancet Neurol
; 20(10): 832-841, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34536405
12.
Clinical Trial and Postmarketing Safety of Onasemnogene Abeparvovec Therapy.
Drug Saf
; 44(10): 1109-1119, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34383289
13.
Onasemnogene abeparvovec gene therapy for symptomatic infantile-onset spinal muscular atrophy in patients with two copies of SMN2 (STR1VE): an open-label, single-arm, multicentre, phase 3 trial.
Lancet Neurol
; 20(4): 284-293, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33743238
14.
Cortisol response to individualised graded insulin infusions: a reproducible biomarker for CNS compounds inhibiting HPA activation.
Br J Clin Pharmacol
; 70(6): 886-94, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21175444
15.
Meta-analysis of suicide-related behavior events in patients treated with atomoxetine.
J Am Acad Child Adolesc Psychiatry
; 47(2): 209-218, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18176331
16.
Group II metabotropic glutamate receptor agonist prodrugs LY2979165 and LY2140023 attenuate the functional imaging response to ketamine in healthy subjects.
Psychopharmacology (Berl)
; 235(7): 1875-1886, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29564482
17.
Meta-analysis of aggression or hostility events in randomized, controlled clinical trials of atomoxetine for ADHD.
Biol Psychiatry
; 61(5): 713-9, 2007 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16996485
18.
Meta-analysis of aggression and/or hostility-related events in children and adolescents treated with fluoxetine compared with placebo.
J Child Adolesc Psychopharmacol
; 17(5): 713-8, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17979590
19.
Correction to: Clinical Trial and Postmarketing Safety of Onasemnogene Abeparvovec Therapy.
Drug Saf
; 45(2): 191-192, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34940960
20.
Volumetric MRI measurement of caudate nuclei in antipsychotic-naive patients suffering from a first episode of psychosis.
J Psychiatr Res
; 39(4): 365-70, 2005 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15804386