Positive coping style reduction in elderly end-stage renal disease patients: mediating role of white matter mean diffusivity.

PURPOSE: The aim of this study was to explore elderly patients with end-stage renal disease (ESRD) white matter changes, the relationship between white matter (WM) abnormalities and emotional regulation strategies, coping styles in elderly ESRD patients. METHODS: Twenty-eight elderly ESRD patients and twenty-eight sex and age matched healthy controls (HC) were included in this study. Tract-based spatial statistic (TBSS) was used to investigate the microstructural changes of WM. Two questionnaires were used to measure emotional regulation strategies and coping styles. RESULTS: Neuroimaging analysis showed that the damage of WM structure was widespread in elderly ESRD patients. Psychological test results showed that there were differences in emotional regulation strategies and coping styles between elderly ESRD patients and HC. Furthermore, mediating analysis showed that the mean diffusivity (MD) of the significantly different brain regions played a complete mediating role between group and positive coping style. CONCLUSION: These results suggest that the integrity of WM, emotional regulation strategies and coping styles play an important role in ESRD patients. Our findings provide evidence that positive coping style may be fully mediated by MD. These results may help us develop new ways to treat and prevent physical and psychological problems in elderly ESRD hemodialysis patients.

Personality Traits and Quality of Life Among Older Adults: The Chain Mediating Effects of Perceived Social Support and Positive Coping Styles.

The pathways between personality traits and older adults' quality of life (QOL) have been well studied. However, perceived social support and positive coping styles should not be ignored by older adults' QOL. Hence, this study examines the chain mediating role of perceived social support and positive coping styles between personality traits and older adults' QOL. In total, 230 older individuals (Meanage = 69.43, SDage = 7.23, age range from 60 to 93) participated in this study. All older people provided a rating of QOL and perceived social support, the Chinese Big Five personality, and positive coping styles. (1a) the five personality traits of older adults were significantly associated with QOL; (2b) perceived social support mediated the relationship between three personality traits (neuroticism, extraversion, and agreeableness) and QOL; (3c) positive coping styles played a mediator role in the personality traits (neuroticism, extraversion, and agreeableness) and QOL; (4d) perceived social support and positive coping styles had a significant chain mediating effect on the three dimensions of personality traits (neuroticism, extraversion, and agreeableness) and QOL. As mediating influences, social support and positive coping styles can be applied to efforts to promote QOL for older adults who share the personality traits of neuroticism, extraversion, and agreeableness.