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1.
Efficacy and Safety of Ensitrelvir in Patients With Mild-to-Moderate Coronavirus Disease 2019: The Phase 2b Part of a Randomized, Placebo-Controlled, Phase 2/3 Study.
Clin Infect Dis
; 76(8): 1403-1411, 2023 04 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36477182
2.
Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts.
N Engl J Med
; 383(4): 309-320, 2020 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32640124
3.
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model.
PLoS Pathog
; 17(5): e1009527, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33956888
4.
Baloxavir safety and clinical and virologic outcomes in influenza virus-infected pediatric patients by age group: age-based pooled analysis of two pediatric studies conducted in Japan.
BMC Pediatr
; 23(1): 35, 2023 01 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36681802
5.
A Randomized Phase 2/3 Study of Ensitrelvir, a Novel Oral SARS-CoV-2 3C-Like Protease Inhibitor, in Japanese Patients with Mild-to-Moderate COVID-19 or Asymptomatic SARS-CoV-2 Infection: Results of the Phase 2a Part.
Antimicrob Agents Chemother
; 66(10): e0069722, 2022 10 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36098519
6.
Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission.
PLoS Pathog
; 16(4): e1008395, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32294137
7.
Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents.
N Engl J Med
; 379(10): 913-923, 2018 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30184455
8.
Open-label study of the safety, pharmacokinetics, and effectiveness of a 2 mg/kg dose of baloxavir marboxil 2% granules in children <20 kg with influenza.
J Infect Chemother
; 27(8): 1223-1229, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34045119
9.
Treatment-Emergent Influenza Variant Viruses With Reduced Baloxavir Susceptibility: Impact on Clinical and Virologic Outcomes in Uncomplicated Influenza.
J Infect Dis
; 221(3): 346-355, 2020 01 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31309975
10.
Baloxavir Marboxil in Japanese Pediatric Patients With Influenza: Safety and Clinical and Virologic Outcomes.
Clin Infect Dis
; 71(4): 971-981, 2020 08 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31538644
11.
A Novel Mouse Model of Acute-on-Chronic Cholestatic Alcoholic Liver Disease: A Systems Biology Comparison With Human Alcoholic Hepatitis.
Alcohol Clin Exp Res
; 44(1): 87-101, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31710124
12.
Effects of pirfenidone in acute and sub-chronic liver fibrosis, and an initiation-promotion cancer model in the mouse.
Toxicol Appl Pharmacol
; 339: 1-9, 2018 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29197520
13.
Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice.
Mol Carcinog
; 55(5): 808-17, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25865624
14.
A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways.
Toxicol Appl Pharmacol
; 310: 129-139, 2016 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27641628
15.
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.
J Toxicol Environ Health A
; 78(1): 15-31, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25424544
16.
Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.
J Toxicol Environ Health A
; 78(1): 32-49, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25424545
17.
Plasma miR-208 as a useful biomarker for drug-induced cardiotoxicity in rats.
J Appl Toxicol
; 35(2): 173-80, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25092230
18.
Diagnostic and predictive performance and standardized threshold of traditional biomarkers for drug-induced liver injury in rats.
J Appl Toxicol
; 35(2): 165-72, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25186495
19.
Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice.
Int J Cancer
; 134(12): 2778-88, 2014 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24242335
20.
Identification of metabolomic biomarkers for drug-induced acute kidney injury in rats.
J Appl Toxicol
; 34(10): 1087-95, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24114878