Detalles de la búsqueda
1.
Analysis of structure-activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors.
Bioorg Med Chem
; 95: 117502, 2023 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37866089
2.
Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone.
Bioorg Chem
; 128: 105905, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35710525
3.
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy.
Bioorg Chem
; 77: 600-607, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29494816
4.
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine.
Anesthesiology
; 126(5): 952-966, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28212204
5.
Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors.
Bioorg Med Chem Lett
; 24(15): 3403-6, 2014 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24939758
6.
Discovery, structure-activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists.
Bioorg Med Chem
; 22(17): 4694-703, 2014 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25087049
7.
A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects.
Eur J Med Chem
; 258: 115608, 2023 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37437352
8.
Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching.
Anal Chem
; 84(15): 6391-9, 2012 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22712523
9.
Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation.
Eur J Med Chem
; 243: 114728, 2022 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36084534
10.
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design.
Eur J Med Chem
; 229: 114043, 2022 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34929581
11.
Radical reductions of alkyl halides bearing electron withdrawing groups with N-heterocyclic carbene boranes.
Org Biomol Chem
; 9(9): 3415-20, 2011 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21423918
12.
Boryltrihydroborate: synthesis, structure, and reactivity as a reductant in ionic, organometallic, and radical reactions.
J Am Chem Soc
; 132(33): 11449-51, 2010 Aug 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-20677751
13.
EPR studies of the generation, structure, and reactivity of n-heterocyclic carbene borane radicals.
J Am Chem Soc
; 132(7): 2350-8, 2010 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-20104896
14.
Using a threading-followed-by-swelling approach to synthesize [2]rotaxanes.
Chemistry
; 16(23): 6950-60, 2010 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20449856
15.
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery.
Sci Rep
; 10(1): 16771, 2020 10 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33033310
16.
BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine.
Neuropharmacology
; 166: 107678, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31278929
17.
Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors.
J Med Chem
; 63(4): 1642-1659, 2020 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31961685
18.
N-heterocyclic carbene boryl radicals: a new class of boron-centered radical.
J Am Chem Soc
; 131(31): 11256-62, 2009 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-19606860
19.
DAST-mediated regioselective anomeric group migration in saccharides.
J Org Chem
; 74(11): 4041-8, 2009 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-19441783
20.
Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice.
Sci Rep
; 9(1): 2405, 2019 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30787373