RESUMEN
Biomolecular radiation damage is largely mediated by radicals and low-energy electrons formed by water ionization rather than by direct ionization of biomolecules. It was speculated that such an extensive, localized water ionization can be caused by ultrafast processes following excitation by core-level ionization of hydrated metal ions. In this model, ions relax via a cascade of local Auger-Meitner and, importantly, non-local charge- and energy-transfer processes involving the water environment. Here, we experimentally and theoretically show that, for solvated paradigmatic intermediate-mass Al3+ ions, electronic relaxation involves two sequential solute-solvent electron transfer-mediated decay processes. The electron transfer-mediated decay steps correspond to sequential relaxation from Al5+ to Al3+ accompanied by formation of four ionized water molecules and two low-energy electrons. Such charge multiplication and the generated highly reactive species are expected to initiate cascades of radical reactions.
RESUMEN
This study has demonstrated that subjects of different "immune health" status also differ in the activity of the vegetative nervous system. Aerocryotherapy was shown to have stimulatory effect on the immune system and decreased the hyperactivity of the parasympathetic nervous system especially in people suffering immune insufficiency.
Asunto(s)
Sistema Nervioso Autónomo/fisiología , Fenómenos Fisiológicos Cardiovasculares , Crioterapia/métodos , Inmunidad Innata , Infecciones del Sistema Respiratorio/terapia , Virosis/terapia , Enfermedad Aguda , Adulto , Interpretación Estadística de Datos , Humanos , Inmunidad Celular/fisiología , Nitrógeno/administración & dosificación , Nitrógeno/uso terapéutico , Infecciones del Sistema Respiratorio/inmunología , Infecciones del Sistema Respiratorio/fisiopatología , Infecciones del Sistema Respiratorio/virología , Resultado del Tratamiento , Virosis/inmunología , Virosis/fisiopatología , Adulto JovenRESUMEN
The destruction of nutrition traditional structure and imbalance of food allowance by the basic kinds of plastic and energy materials impose a negative mark on efficiency of immune protection of north Aboriginals.
Asunto(s)
Metabolismo Energético/inmunología , Conducta Alimentaria/etnología , Estado Nutricional/inmunología , Femenino , Humanos , Masculino , Siberia/etnologíaRESUMEN
The rate of respiratory viral infection in the history affects the pattern of manifestations of pulmonary tuberculosis. With the manifestation of tuberculous infection, there is a reduction in the level of mature T lymphocytes and an increase in the values of monocytic oxygen-dependent metabolism (spontaneous and stimulated HCT test). Reductions in the level of activated proliferative cell markers of the lymphocytic link (CD38+ cells, expression of receptors for IL-2, Class II HLA antigens, and receptors for transferrin), in the absolute count of B lymphocytes, in the level of EA-POM and EA-phagocytosis of monocytes and an increase in the concentration of IgM occur more than 3 times a year in patients with respiratory viral infections.
Asunto(s)
Inmunoglobulinas/inmunología , Neutrófilos/inmunología , Infecciones del Sistema Respiratorio/complicaciones , Infecciones del Sistema Respiratorio/virología , Tuberculosis Pulmonar/complicaciones , Tuberculosis Pulmonar/inmunología , Adolescente , Adulto , Femenino , Humanos , MasculinoRESUMEN
The results of studying of correlation lipid composition of blood and immunity are presented. Features of nutrition of patients with chronic infectious-inflammatory diseases in Tyumen region are also analyzed. Decrease of protein, fat and carbohydrates in diet of patients was found. Level of cholesterol and triglycerides in plasma of patient was increased.
Asunto(s)
Infecciones/sangre , Inflamación/sangre , Lípidos/sangre , Adulto , Estudios de Casos y Controles , Humanos , Persona de Mediana Edad , Federación de RusiaRESUMEN
The decrease of calorie in ration content, insufficient consumption of proteins and lipids was found among the patients in the condition of penitentiary establishment, it results in decrease of characteristics of natural immunity and resistibility to various infections agents, to the action of toxic substances, stress and other negative conditions that take place in penitentiary establishment a disbalanse of regulatory subpopulation of cellular consistent of immunity and predominance of suppressive-cytotoxic influence was observed among the patients of the penitentiary establishment (with a reduced ration of nutrition) over halt a year. Considering a health problem, in the establishments of imprisonment one may probably state that a reduced ration of nutrition is one of the main courses of immune homeostasis shift leasing in the basis of specific and non-specific phenomena of morbidity.
Asunto(s)
Sistema Inmunológico/fisiología , Estado Nutricional , Prisiones , Adolescente , Adulto , Aminoácidos/farmacología , Linfocitos B/inmunología , Ingestión de Energía , Humanos , Inmunoglobulina A/sangre , Masculino , Monocitos/inmunología , Federación de Rusia , Vitaminas/farmacologíaAsunto(s)
Dieta , Leucocitos Mononucleares/inmunología , Estado Nutricional , Antígenos CD/sangre , Eosinófilos/inmunología , Homeostasis , Humanos , Inmunoglobulina A/sangre , Inmunoglobulina G/sangre , Inmunoglobulina M/sangre , Recuento de Leucocitos , Monocitos/inmunología , Neutrófilos/inmunología , Federación de Rusia , Linfocitos T/inmunologíaRESUMEN
Eleven parents of 8-year-olds suffering from PKU were interviewed about their experiences with the disease. The narrative interview method was selected in order to expose the problems from the parents' angle without influence through expert prompting. On being notified of the diagnosis after birth, the parents were extremely shocked and went through emotional crises and adjustment problems during the first 12 months. The narcissistic hurt of not having a healthy child was compounded by problems with dietary technique. The behaviour and development of the children themselves were no particular problem. Handling the diet ranked highest among the problems raised by the parents. It turned out that all the parents did not always apply the diet strictly and deviated from it. The underlying reason was a compromise between an ideal attitude towards the diet with the accompanying experience of loss and guilt, and the goal of undisturbed personality development of the child. Discussion groups with therapeutic support are suggested as a way of relieving the burden on the parents.