Detalles de la búsqueda
1.
SIG-1451, a Novel, Non-Steroidal Anti-Inflammatory Compound, Attenuates Light-Induced Photoreceptor Degeneration by Affecting the Inflammatory Process.
Int J Mol Sci
; 23(15)2022 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35955937
2.
Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
Proc Natl Acad Sci U S A
; 115(51): E12053-E12062, 2018 12 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30509990
3.
SIG1459: A novel phytyl-cysteine derived TLR2 modulator with in vitro and clinical anti-acne activity.
Exp Dermatol
; 27(9): 993-999, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29797368
4.
Dual κ-agonist/µ-antagonist opioid receptor modulation reduces levodopa-induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of Parkinson disease.
Ann Neurol
; 77(6): 930-41, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25820831
5.
Enhanced phosphatase activity attenuates α-synucleinopathy in a mouse model.
J Neurosci
; 31(19): 6963-71, 2011 May 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-21562258
6.
Modifying naloxone to reverse fentanyl-induced overdose.
Int J Pharm
; 611: 121326, 2022 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34848365
7.
Does a hypoxic injury from a non-fatal overdose lead to an Alzheimer Disease?
Neurochem Int
; 143: 104936, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33309980
8.
NB-33, a bioreversible opioid derivative of Nalbuphine, shows enhanced pharmacodynamics.
Eur J Pharm Sci
; 159: 105734, 2021 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33515698
9.
A vicious cycle of neuropathological, cognitive and behavioural sequelae of repeated opioid overdose.
Int J Drug Policy
; 97: 103362, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34314956
10.
HYVIA™: A novel, topical chia seed extract that improves skin hydration.
J Cosmet Dermatol
; 19(9): 2386-2393, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32378329
11.
SIG-1273 protects skin against urban air pollution and when formulated in AgeIQ™ Night Cream anti-aging benefits clinically demonstrated.
J Cosmet Dermatol
; 18(5): 1366-1371, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30456862
12.
Pilot study demonstrates N-Succinyl-S-farnesyl-L-cysteine reduces erythema and inflammatory lesions in rosacea subjects.
J Cosmet Dermatol
; 22(9): 2622-2623, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37073424
13.
Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease.
J Neuropathol Exp Neurol
; 77(2): 139-148, 2018 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29281045
14.
Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid.
PLoS One
; 12(12): e0189413, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29253878
15.
N-Acetylglutaminoyl-S-farnesyl-L-cysteine (SIG-1191): an anti-inflammatory molecule that increases the expression of the aquaglyceroporin, aquaporin-3, in human keratinocytes.
Arch Dermatol Res
; 309(2): 103-110, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-27988893
16.
In vitro and clinical evaluation of SIG1273: a cosmetic functional ingredient with a broad spectrum of anti-aging and antioxidant activities.
J Cosmet Dermatol
; 15(2): 150-7, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-26754448
17.
Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies.
Ann Clin Transl Neurol
; 3(10): 769-780, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27752512
18.
Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.
Neurobiol Aging
; 35(12): 2701-2712, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25034344
19.
Neuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's disease.
Neurotherapeutics
; 10(1): 143-53, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23296837
20.
Targeting phosphatases as the next generation of disease modifying therapeutics for Parkinson's disease.
Neurochem Int
; 61(6): 899-906, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22342821