RESUMEN
The purpose of the present study was to evaluate histologically in beagle dogs the healing in acute dehiscence type defects following treatment with open flap debridement (OFD) with or without porous biphasic calcium phosphate (PBCP). Alveolar bone dehiscence defects were surgically created bilaterally at the labial aspects of maxillary third incisors in 12 beagle dogs. After root conditioning with ethylenediaminetetraacetate, PBCP was filled in the defects and the contralaterals were cured with OFD. Two fluorochrome labelings were administered at the 7th and 11th weeks, respectively. Four dogs were killed at the 12, 16, and 24 weeks, respectively. Histological observations were processed through microcomputed tomographic imaging, fluorescence microscope, and light microscopy. The formation of new regenerated tissues was assessed histomorphometrically. The results revealed the healing after treatments with PBCP evidenced a new attachment apparatus and that with OFD supported periodontal repair. In PBCP groups, the amount of new bone varied from 1.15 to 3.86 mm (23-77.2% of the original defect size), while only 0.3 to 1.04 mm (6-20.8%) in OFD group. The amount of new cementum in PBCP varied from 1.18 to 4.16 mm (23.6-82.3%), while only 0.67 to 1.15 mm (13.4-23%) in OFD group. The amount of periodontal ligament in PBCP varied from 1.03 to 4.12 mm (20.6-82.4%), while only 0 to 0.93 mm (0-18.6%) in OFD group. There was significantly more regenerated tissue in PBCP groups compared to OFD procedures (p < 0.01). The present results indicate that PBCP may enhance periodontal regeneration in acute-type labial dehiscence defects.
Asunto(s)
Pérdida de Hueso Alveolar/cirugía , Sustitutos de Huesos/uso terapéutico , Cerámica , Hidroxiapatitas/uso terapéutico , Proceso Alveolar/efectos de los fármacos , Proceso Alveolar/patología , Animales , Regeneración Ósea/efectos de los fármacos , Quelantes/uso terapéutico , Desbridamiento , Cemento Dental/efectos de los fármacos , Cemento Dental/patología , Perros , Ácido Edético/uso terapéutico , Colorantes Fluorescentes , Procesamiento de Imagen Asistido por Computador/métodos , Imagenología Tridimensional/métodos , Incisivo/patología , Masculino , Microscopía Fluorescente , Ligamento Periodontal/efectos de los fármacos , Ligamento Periodontal/patología , Fenoles , Regeneración/efectos de los fármacos , Sulfóxidos , Colgajos Quirúrgicos , Tetraciclina , Factores de Tiempo , Raíz del Diente/efectos de los fármacos , Cicatrización de Heridas/fisiología , Microtomografía por Rayos X , XilenosRESUMEN
OBJECTIVE: To investigate the effects of skeletal Class III malocclusion in mixed dentition on speech articulation and to look for which factors lead to the speech errors. METHODS: Thirty-eight children with skeletal Angle Ill malocclusion in mixed dentition were selected as a sample group and 40 children with normal occlusion in mixed dentition as a control group. Two phoneticians evaluated their articulations and wrote down error phonemes respectively. The correlation analysis was undertaken between the number of errors and the measurements of patients' cephalometry. RESULTS: The number of errors were correlated significantly with overbite, UI-LI, OBJ (OB+OJ) and TD-PW. CONCLUSION: There is articulatory malfunction in the majority of skeletal Angle III malocclusion patients in mixed dentition. Articulatory malfunction is related to the position of incisors and the tongue.