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1.
Low molecular weight acids and OATP1B mediated hepatic clearance: In vitro and in vivo evaluation using novel hypoxia-inducible factor prolyl hydroxylase inhibitors (Dustats).
Drug Metab Dispos
; 2024 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38388380
2.
Utilization of Rosuvastatin and Endogenous Biomarkers in Evaluating the Impact of Ritlecitinib on BCRP, OATP1B1, and OAT3 Transporter Activity.
Pharm Res
; 40(11): 2639-2651, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37561322
3.
Organic Anion-Transporting Polypeptide 1B1/1B3-Mediated Hepatic Uptake Determines the Pharmacokinetics of Large Lipophilic Acids: In Vitro-In Vivo Evaluation in Cynomolgus Monkey.
J Pharmacol Exp Ther
; 377(1): 169-180, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33509903
4.
In Vitro-In Vivo Extrapolation of Key Transporter Activity at the Blood-Brain Barrier.
Drug Metab Dispos
; 47(4): 405-411, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30683809
5.
Mechanistic Determinants of Daprodustat Drug-Drug Interactions and Pharmacokinetics in Hepatic Dysfunction and Chronic Kidney Disease: Significance of OATP1B-CYP2C8 Interplay.
Clin Pharmacol Ther
; 115(6): 1336-1345, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38404228
6.
Evaluation of 14 PFAS for permeability and organic anion transporter interactions: Implications for renal clearance in humans.
Chemosphere
; 361: 142390, 2024 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-38801906
7.
In vitro characterization of axitinib interactions with human efflux and hepatic uptake transporters: implications for disposition and drug interactions.
Drug Metab Dispos
; 41(8): 1575-83, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23729661
8.
Elucidation of the biochemical basis for a clinical drug-drug interaction between atorvastatin and 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methyl benzoic acid (CP-778875), a subtype selective agonist of the peroxisome proliferator-activated receptor alpha.
Xenobiotica
; 43(11): 963-72, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23631744
9.
Translatability of in vitro Inhibition Potency to in vivo P-Glycoprotein Mediated Drug Interaction Risk.
J Pharm Sci
; 112(6): 1715-1723, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36682487
10.
Biomarker-Informed Model-Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug-Drug Interactions.
Clin Pharmacol Ther
; 111(2): 404-415, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34605015
11.
Quantitative prediction of breast cancer resistant protein mediated drug-drug interactions using physiologically-based pharmacokinetic modeling.
CPT Pharmacometrics Syst Pharmacol
; 10(9): 1018-1031, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34164937
12.
Harnessing Preclinical Data as a Predictive Tool for Human Brain Tissue Targeting.
ACS Chem Neurosci
; 12(6): 1007-1017, 2021 03 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33651587
13.
Prediction of Human Brain Penetration of P-glycoprotein and Breast Cancer Resistance Protein Substrates Using In Vitro Transporter Studies and Animal Models.
J Pharm Sci
; 107(8): 2225-2235, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29608887
14.
The bacterial microbiota of Stolotermes ruficeps (Stolotermitidae), a phylogenetically basal termite endemic to New Zealand.
FEMS Microbiol Ecol
; 90(3): 678-88, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25196080
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