[The technique for demonstrating the renal arteries during an excretion urogram. Bolus technique--timing--simultaneous tomography (author's transl)]. / Technik der Nierenarteriendarstellung im Rahmen des Ausscheidungsurogrammes Bolustechnik--Zeitbestimmung--Simultantomographie.

The aorta and renal arteries, as far as their intrarenal branches, can be demonstrated in the course of an excretion urogram if the contrast medium (1 ml/kg body weight, maximum 60 ml) is injected at a flow rate of 10 to 15 ml/sec (Bolus technique). The intravenous bolus injection was carried out in 180 patients without any significant complications. In order to obtain the correct timing on a single film it is necessary to determine the circulation time from the arm vein to the abdominal aorta in each individual. The addition of 0.2 to 0.3 mCi 99mTc to the contrast medium makes it possible to determine the circulation time accurately. This varied from 9 to 22 seconds. By using tomography with 1 cm cuts and a 4.5 cm format, it was possible to show the left or right renal arteries from the aorta to their intrarenal branches in 82% patients. In 126 (70%) of the 180 patients, both renal arteries were demonstrated. The demonstration of renal arteries during the course of an excretion urogram represents an advance on the conventional technique. The indications are discussed.

Fracture healing under factor XIII medication.

Following application of factor XIII for 3 weeks bone healing was studied in Sprague-Dawley rats on the 20th postoperatively day qualitatively (radiographs, scintigraphy) and quantitatively (determination of callus thickness, of bone mineral content, and scintillation counting). No significant difference could be detected between animals treated with factor XIII and animals which served as controls. Therefore, a stimulating effect of factor XIII upon bone healing can not be expected in case of a normal factor XIII serum-level. The application of factor XIII is indicated only in high risk patients with a low factor XIII serum-level.

[Model for the study of influences on fracture healing. Animal experiments]. / Modell zum Studium von Einflüssen auf die Frakturheilung. Tierexperimentelle Untersuchungen.

Primary and secondary bone healing were studied for 30 and 60 days, respectively, by means of X rays, scintigraphy, determination of callus thickness, scintillation counter, and determination of bone mineral content. Primary bone healing was terminated after 30 days, secondary healing after 60 days. Scintillation counting proved to be a quantitative method, the other methods serving as controls. The different influences on bone healing can be quantitatively studied by means of this model.

[Assessment of the risk of occipitocervical dislocation in inflammatory rheumatic diseases]. / Zur Risikobeurteilung occipito-cervicaler Dislokationen bei entzündlich-rheumatischen Krankheiten.

In this mainly retrospective study we examined by means of tomographic and computer tomographic findings various manifestations and courses of cranio-cervical subluxations in chronic inflammatory rheumatic diseases and the resulting neurological complications. Even in marked cranio-cervical subluxations neurological complications are rarely observed. More serious anterior atlanto-axial subluxation represents the highest risk for spinal cord injury as a result of the mobility of the atlas. A subsequent vertical (upward) atlanto-axial subluxation occurring particularly in serious courses of illness reduces this risk since it is generally to be found together with a fixation of the atlas. This also applies to a possible pseudobasilar invagination. As a result of our studies we found ways of using CT to achieve further information. We could also derive guidelines for the indication of operative treatment. In view of the further development of surgical methods and variations in operative risk dependent on the preoperative situation, these recommendations can only be provisional.

[Correction of tetralogy of Fallot and its influence to oxygen transport and lung changes. Part II: Lung changes (author's transl)]. / Der Einfluss der Korrektur einer Fallotschen Tetralogie auf Sauerstofftransport und Lunge. Teil II: Lungenveränderungen

22 children got lung scans 3 weeks respectively 12 months after the correction of a tetralogy of Fallot. In 18 cases previous operations were done: 12 times a Blalock-Taussig shunt and 6 times a Brock procedure. For the scan 20-70 mu diameter albumin macrospheres were used, which were labeled with Technetium 99m. The following pathologicla lung changes were seen: 1. Loss of perfusion, typical after Blalock-Taussig shunt procedure; these findings were always on the left side, the site of the anastomosis. 2. Anomalous flow distrubution (=more spheres in the upper than in the lower lobe) in the left lung; these changes were also caused by the Blalock-Taussing shunts, but disappeared within the one year follow-up after the correction. 3. Intrapulmonary rigt-left shunts (according to the dilatation of the alveolar capillaries). These decreased within one year from 9.9+/-1.3 to 4.6+/-0.9%.