Meta-analysis of citrus-derived additives on chicken meat quality and safety: a comprehensive evaluation of acceptability, physicochemical properties, and microbial contamination.

Citrus represents a valuable repository of antioxidant substances that possess the potential for the preservation of meat quality. This meta-analysis aimed to comprehensively assess the impact of citrus additives on the quality and safety of chicken meat. Adhering to the PRISMA protocol, we initially identified 103 relevant studies, from which 20 articles meeting specific criteria were selected for database construction. Through the amalgamation of diverse individual studies, this research provides a comprehensive overview of chicken meat quality and safety, with a specific focus on the influence of citrus-derived additives. Minimal alterations were observed in the nutritional quality of chicken meat concerning storage temperature and duration. The findings demonstrated a significant reduction in aerobic bacterial levels, with Citrus aurantiifolia exhibiting the highest efficacy (P < 0.01). Both extracted and nonextracted citrus components, applied through coating, curing, and marinating, effectively mitigated bacterial contamination. Notably, thiobarbituric acid reactive substances (TBARS) concentrations were significantly reduced, particularly with Citrus hystrix (P < 0.01). Total volatile base nitrogen (TVBN), an indicator of protein degradation, exhibited a decrease, with citrus extract displaying enhanced efficacy (P < 0.01). Chemical composition changes were marginal, except for a protein increase after storage (P < 0.01). Hedonic testing revealed varied preferences, indicating improvements in flavor, juiciness, and overall acceptability after storage (P < 0.01). The study underscores the effectiveness of citrus additives in preserving chicken meat quality, highlighting their antibacterial and antioxidant properties, despite some observed alterations in texture and chemical composition. Citrus additives have been proven successful in 1) mitigating adverse effects on chicken meat during storage, especially with Citrus hystrix exhibiting potent antimicrobial properties, and 2) enhancing the hedonic quality of chicken meat. This research strongly advocates for the application of citrus additives to uphold the quality and safety of chicken meat.

Meta-analysis of the effects of gamma irradiation on chicken meat and meat product quality.

Background and Aim: Irradiation is one of the most effective microbial decontamination treatments for eliminating foodborne pathogens and enhancing chicken meat safety. The effect of gamma irradiation on the overall quality of chicken meat and its products must be observed to provide a comprehensive explanation to the public. This meta-analysis examined the effects of gamma irradiation on the oxidation parameters, microbial activity, physicochemical characteristics, sensory parameters, and nutrient quality of chicken meat and meat products. Materials and Methods: We conducted a literature search using various search engines (Scopus®, PubMed®, and Google Scholar®) with "irradiation," "gamma," "chicken," and "meat" as keywords. Gamma irradiation treatment was set as a fixed effect, and the difference between experiments was set as a random effect. This study used a mixed-model methodology. After evaluation, we selected 43 articles (86 studies) for inclusion in the database. Results: Gamma irradiation significantly increased (p < 0.01) thiobarbituric acid-reactive substance levels on days 0, 7, and 14 of storage. Gamma irradiation reduced total aerobic bacteria, coliforms, Salmonella, yeast, and mold activity (p < 0.01). According to our meta-analysis, 21.75 kGy was the best dose for reducing total aerobic bacteria. On day 0, gamma irradiation did not affect the color parameters (L*, a*, b*). However, a significant difference (p < 0.01) was noted for a* and b* parameters between the control and irradiation treatments at 7 and 14 days. Although irradiation treatment was less consistent in sensory parameters, overall acceptability decreased on days 0, 7, and 14 after storage (p < 0.05). Regarding nutrient composition, gamma irradiation reduced moisture content and free fatty acid (FFA) content (p < 0.05). Although irradiation significantly reduces the microbial population, it increases the oxidation of chicken meat and its products. Irradiation decreases FFA content and overall acceptability, but it does not affect flavor, tenderness, juiciness, or cooking loss. Conclusion: Gamma irradiation positively reduces the microbial activity in chicken meat and its products but increases the oxidation parameters. Although gamma irradiation does not alter the flavor, tenderness, juiciness, or cooking loss, gamma irradiation can reduce the FFA content and overall acceptability.

Cardioembolic stroke with hemorrhagic transformation in atrial fibrillation patients on anticoagulant therapy: A case report.

Cardioembolic stroke is the second leading cause of mortality and the leading cause of long-term morbidity. Embolisms of cardiac origin, such as atrial fibrillation, represent about one-fifth of all ischemic strokes. Patients with acute atrial fibrillation frequently require anticoagulation, which increases the risk of hemorrhagic transformation. A 67-year-old woman was brought to the Emergency Department with decreased consciousness, weakness on the left side, facial expression, and slurred speech. The patient had a history of atrial fibrillation and was taking regular medications acarbose, warfarin, candesartan and bisoprolol. She has had an ischemic stroke about a year ago. Left hemiparesis, hyperreflexias, pathologic reflexes, and central type of facial nerve palsy were found. The CT-Scan results revealed hyperacute to acute thromboembolic cerebral infraction in the frontotemporoparietal lobe to the right basal ganglia accompanied by hemorrhagic transformation. Massive cerebral infarction, history of previous stroke, and use of anticoagulants are among the greatest risk factors for hemorrhagic transformation in these patients. The use of warfarin should be of particular concern to the clinician, because hemorrhagic transformation is associated with poorer functional outcome and morbidity and mortality.

The Effect of Alginate Concentration on Crystallinity, Morphology, and Thermal Stability Properties of Hydroxyapatite/Alginate Composite.

Hydroxyapatite (HAp) has been used for various applications such as orthopedics, drug delivery material, and bone tissue engineering. It is well known that HAp has a good biocompatibility and osteoconductivity, so HAp can be used in biomedical applications. Hydroxyapatite can be combined with other materials, in particular polymer, to expand its range of applications. In this study, the polymer that will be used as a support for the HAp composite is alginate (Alg). The HAp/Alg composite has been synthesized by the precipitation method. The XRD results show that the crystal system of HAp was hexagonal. The spheric-like shaped particles can be observed from SEM images, and particle size distribution spread from 400 to 1100 nm. The EDS spectrum exhibited the peak of Ca, C, P, and O elements, indicating that alginate had interacted with hydroxyapatite in the synthesized composite. The as-fabricated composite showed not only good crystallinity but also high thermal resistance. Thermogravimetric-differential thermal analysis (TGA-DTA) revealed that the HAp/Alg composites have a constant weight at 750 °C, so it might be applied in advanced applications such as bioimaging, drug carrier, and other cancer treatments.

A meta-analysis of the effects of clay mineral supplementation on alkaline phosphatase, broiler health, and performance.

The crucial constraint in the broiler production sector is feed efficiency; many feed additives have been widely employed to increase broiler growth. Nonetheless, some of these substances exacerbate health and animal-based food product safety concerns. This meta-analysis examines the effect of clay minerals on alkaline phosphatase (ALP), broiler health, and performance. Metadata was constructed from 369 data items that were harvested from 86 studies. The addition of clay minerals was set as a fixed effect and the difference between experiments was established as a random effect. The metadata were fitted using a linear mixed model. Due to the presence of clay minerals, growth performance as assessed by body weight (BW), average daily gain (ADG), and performance efficiency index (PEI) increased significantly (P < 0.01). In the total period, the increases of BW, ADG, and PEI were 4.12 g, 0.0714 g/d, and 0.648, respectively, per unit of clay minerals added. Clay minerals did not affect blood serum parameters (e.g., ALP and calcium). The IgA and IgM concentrations in the jejunum and ileum were significantly greater (P < 0.01) in the starter phase. Among clay minerals, broilers fed diets with aluminosilicate, halloysite, kaolin, and zeolite consistently exhibited higher (P < 0.05) BW, ADG, PEI, and lower feed conversion ratio (P < 0.05) in the finisher phase. Aluminosilicate was the only clay that increased (P < 0.05) secretory IgA concentration in both jejunum and ileum. In conclusion, clay minerals could be used as a growth promoter, especially during the finisher phase, without adversely affecting feed intake, liver function, and mineral metabolism in broiler chickens. Aluminosilicate was superior in improving the mucosal immunity status of broiler chickens.

Factors Affecting Uncontrolled Blood Pressure among Elderly Hypertensive Patients in Pekanbaru City, Indonesia.

BACKGROUND: The highest prevalence of hypertension is among older adults. Although older adults with hypertension have already controlled their blood pressure by taking antihypertensive drugs, hypertension will still occur when not balanced with a healthy lifestyle. Data from Pekanbaru Municipality Health Department in 2016 showed that hypertension was the most common disease in Pekanbaru City. AIM: The purpose of this study was to determine the factors that influence uncontrolled blood pressure among elderly patients with hypertension at Harapan Raya Pekanbaru Health Center in 2017. MATERIAL AND METHODS: The study employed a cross-sectional design. The sample size comprised 116 elderly patients with hypertension who visited Harapan Raya Community Health Center. The sample criteria were patients aged ≥ 60 years and taking hypertension medication, and subjects were selected using consecutive sampling. The variables collected were demographic characteristics of elderly patients (age, education, sex, and occupation), physical activity, smoking habit, coffee and tea consumption and sodium intake. Statistical analysis involved the chi-square test and multiple logistic regressions. RESULTS: The proportion of elderly hypertensive patients with uncontrolled blood pressure was 52.6%. The most influential variables concerning uncontrolled blood pressure were smoking habit (P-value: 0.004, OR: 5.2 95% CI: 1.71-15.8), no routine for taking antihypertensive drugs (P-value = 0.029 OR = 2.96 95% CI: 1.11-7.86) and sodium intake (P-value: 0.044 OR: 0.264 95% CI: 0.072-0.967). CONCLUSION: The dominant factor influencing uncontrolled blood pressure among the elderly was smoking. Health workers at the Community Health Center are expected to provide education and counselling for elderly patients with hypertension to control their blood pressure by taking antihypertensive drugs regularly and quitting smoking.