Detalles de la búsqueda
1.
Baicalin - 2- ethoxyethyl ester alleviates renal fibrosis by inhibiting PI3K/AKT/NF-κB signaling pathway.
Toxicol Appl Pharmacol
; 483: 116827, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38246290
2.
Catalytic Atroposelective Synthesis of Axially Chiral Azomethine Imines and Neuroprotective Activity Evaluation.
Angew Chem Int Ed Engl
; 63(5): e202312663, 2024 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38032817
3.
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression.
Pharmacol Res
; 187: 106565, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36414124
4.
Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells.
J Enzyme Inhib Med Chem
; 38(1): 2242601, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37533352
5.
Three new tyrosol derivatives from Huangjing wine.
J Asian Nat Prod Res
; 24(11): 1018-1024, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-34842008
6.
The Amomum tsao-ko Essential Oils Inhibited Inflammation and Apoptosis through p38/JNK MAPK Signaling Pathway and Alleviated Gentamicin-Induced Acute Kidney Injury.
Molecules
; 27(20)2022 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36296715
7.
Design, synthesis and biological evaluation of dual mTOR/HDAC6 inhibitors in MDA-MB-231 cells.
Bioorg Med Chem Lett
; 47: 128204, 2021 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34139324
8.
The development of novel cytochrome P450 2J2 (CYP2J2) inhibitor and the underlying interaction between inhibitor and CYP2J2.
J Enzyme Inhib Med Chem
; 36(1): 737-748, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33682565
9.
Atorvastatin Ester Regulates Lipid Metabolism in Hyperlipidemia Rats via the PPAR-signaling Pathway and HMGCR Expression in the Liver.
Int J Mol Sci
; 22(20)2021 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681767
10.
Visual High-Throughput Screening for Developing a Fatty Acid Amide Hydrolase Natural Inhibitor Based on an Enzyme-Activated Fluorescent Probe.
Anal Chem
; 92(14): 9493-9500, 2020 07 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32456414
11.
Ferulin C triggers potent PAK1 and p21-mediated anti-tumor effects in breast cancer by inhibiting Tubulin polymerization in vitro and in vivo.
Pharmacol Res
; 152: 104605, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31863866
12.
Design, synthesis and biological evaluation of 2-indolinone derivatives as PAK1 inhibitors in MDA-MB-231 cells.
Bioorg Med Chem Lett
; 30(17): 127355, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32738980
13.
Design, synthesis and biological evaluation of novel tetrahydrothieno [2,3-c]pyridine substitued benzoyl thiourea derivatives as PAK1 inhibitors in triple negative breast cancer.
J Enzyme Inhib Med Chem
; 35(1): 1524-1538, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32752894
14.
Discovery of novel ATAD2 bromodomain inhibitors that trigger apoptosis and autophagy in breast cells by structure-based virtual screening.
J Enzyme Inhib Med Chem
; 35(1): 713-725, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32174193
15.
Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells.
Bioorg Chem
; 72: 168-181, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28460359
16.
Deconvoluting the relationships between autophagy and metastasis for potential cancer therapy.
Apoptosis
; 21(6): 683-98, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27003389
17.
Design, synthesis and biological evaluation of coumarin derivatives as novel acetylcholinesterase inhibitors that attenuate H2O2-induced apoptosis in SH-SY5Y cells.
Bioorg Chem
; 68: 112-23, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27479541
18.
Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer.
Acta Pharm Sin B
; 14(3): 953-1008, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38487001
19.
Baicalin-2-ethoxyethyl ester alleviates gentamicin-induced acute kidney injury via NF-κB signaling pathway.
Biomed Pharmacother
; 172: 116276, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38377733
20.
Dual-target inhibitors of PARP1 in cancer therapy: A drug discovery perspective.
Drug Discov Today
; 28(7): 103607, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37146962