Speaking up for the invisible minority: First-generation students in higher education.

A first-generation college student is typically defined as a student whose biological parent(s) or guardian(s) never attended college or who started but did not finish college. However, "first-generation" can represent diverse family education situations. The first-generation student community is a multifaceted, and intersectional group of individuals who frequently lack educational/financial resources to succeed and, consequently, require supportive environments with rigorous mentorship. However, first-generation students often do not make their identity as first-generation students known to others due to several psychosocial and academic factors. Therefore, they are often "invisible minorities" in higher education. In this paper, we describe the diverse family situations of first-generation students, further define "first-generation," and suggest five actions that first-generation trainees at the undergraduate/graduate stages can engage in to succeed in an academic climate. We also provide suggestions for mentors to accommodate first-generation students' unique experiences and equip them with tools to deliver intentional mentoring practices. We hope that this paper will help promote first-generation student success throughout the academic pipeline.

Mitigating cold stress in rice: a study of genotype performance and sowing time.

Rice (Oryza sativa L.) is an essential food for half of the global population and is vital in maintaining global food security. Climate change, increasing population and recent incident of COVID pandemic has generated financial burden and threaten the global food security. Due to theses factors rice cultivation also has to face significant challenges. frequent weather changes pose a considerable challenge to agricultural planning, which was previously relaying on consistent seasonal variations. In this context, rice cultivation is particularly sensitive to cold, where its development and productivity inhibited by low temperatures (< 18 °C). Developing rice varietes with low temprature tolerence and good yield potential is one of the major goals of current breeding efforts of plant scientists. For this purpose, short duration and early rice varieties are most favorable to avoid cold stress and yield more in less number of days. this study was designed to investigate the effect of low temperatures on different rice varieties. the study was designed to identify low temprature tolerent genotypes with early and regular cultivation. For this, thirty-four genotypes were evaluated in two gorwing seasons (2018-2019) with four different sowing times. Statistically sowing time showed significant interaction between all yield contributing parameters. The data indicate that exposure to low temperatures during the reproductive phase prolongs the maturation period of the crop, also length of the panicle and the fertility of the spikelets drops, resulting in a significant decrease in the production of sensitive varieties. Some varieties are more sensitive to cold stress compared to others. In the Egyptian context, Giza176, Sakha104, and Sakha107 are recommended for early cultivation, while the genotypes Giza 179, Sakha101, Sakha104, and GZ 9730-1-1-1-1 are indicated for the normal cultivation period. The Sakha104 variety is particularly notable, as it is recommended for both purposes. In addition, the data obtained in this study provide valuable information for selecting rice varieties suitable for double cropping in the North Delta of Egypt. This study also contributes to the existing literature, providing insights into the resilience of rice cultivation in the face of climate change.

Ocular Mucous Membrane Pemphigoid: The Effect of Risk Factors at Presentation on Treatment Outcomes.

PURPOSE: Analyze the influence of risk factors at presentation in the long-term immunosuppressive therapy (IMT) outcomes of ocular mucous membrane pemphigoid (OMMP). DESIGN: Retrospective multicenter study. PARTICIPANTS: Patients with OMMP seen at the Duke Eye Center, Tecnologico de Monterrey, and Hospital Clinic of Barcelona from 1990 to 2022. METHODS: Data at presentation on demographics, direct immunofluorescence, ocular findings, sites of extraocular manifestations (EOMs), and previous treatments in patients with a clinical or laboratory diagnosis of OMMP, were analyzed with multivariable analysis and Kaplan-Meier plots to identify factors associated with adverse outcomes. MAIN OUTCOME MEASURES: (1) Inflammatory control (no conjunctival inflammation in both eyes at 3 months on IMT); (2) relapse (new-onset inflammation after absolute control in either eye); (3) progression (≥ 1 cicatrizing stage progression in either eye); and (4) vision loss (≥ 2 Snellen lines). RESULTS: A total of 117 patients (234 eyes), 61% (71/117) of whom were women, with a mean age of 66.6 (SD: 12.4) years (range: 37-97 years) and median follow-up of 34 months (interquartile range: 16-66 months; range: 3-265 months), were enrolled. Inflammatory control was achieved in 57% of patients (67/117), with high-risk EOM (HR-EOM), including esophageal, nasopharyngeal, and/or genital involvement (adjusted odds ratio [aOR]: 12.51; 95% confidence interval [CI]: 2.61-59.99; P = 0.002) and corneal scarring (aOR: 3.06; 95% CI, 1.15-8.14; P = 0.025), as significant risk factors for persistent inflammation. Disease relapse, progression, and vision loss occurred in 20% of patients (23/117), 12% of patients (14/117), and 27% of patients (32/117), respectively. Baseline corneal scarring was a risk factor for relapse (adjusted hazard ratio: 4.14; 95% CI: 1.61-10.62; P = 0.003), progression (aOR: 11.46; 95% CI: 1.78-73.75; P = 0.010), and vision loss (aOR: 3.51; 95% CI: 1.35-9.10; P = 0.010). HR-EOM was associated with stage progression (aOR, 34.57; 95% CI, 6.57-181.89; P<0.001) and vision loss (aOR, 8.42; 95% CI, 2.50-28.42; P = 0.001). No significant differences were found between IMT regimes and relapse (P = 0.169). CONCLUSIONS: Ocular mucous membrane pemphigoid presenting with HR-EOMs and corneal scarring has an increased risk of stage progression and vision loss. Corneal scarring and severe inflammation at baseline were associated with an increased risk of relapse. A disease progression staging system incorporating both the HR-EOMs and corneal involvement is required to predict the visual outcome of OMMP better. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Changes in GC-MS metabolite profile, antioxidant capacity and anthocyanins content during fermentation of fine-flavor cacao beans from Ecuador.

The fermentation of fine-flavor cacao beans is a key process contributing to the enhancement of organoleptic attributes and monetary benefits for cacao farmers. This work aimed to describe the dynamics of the gas chromatography-mass spectrometry (GC-MS) metabolite profile as well as the antioxidant capacity and anthocyanin contents during fermentation of fine-flavor cacao beans. Samples of Nacional x Trinitario cacao beans were obtained after 0, 24, 48, 72, 96, and 120 hours of spontaneous fermentation. Total phenolic content (TPC), ferric reducing antioxidant power (FRAP), and total anthocyanin content were measured by ultraviolet-visible (UV-Vis) spectrophotometry. Volatiles were adsorbed by headspace solid phase microextraction (HS-SPME) while other metabolites were assessed by an extraction-derivatization method followed by gas chromatography-mass spectrometry (GC-MS) detection and identification. Thirty-two aroma-active compounds were identified in the samples, including 17 fruity, and 9 floral-like volatiles as well as metabolites with caramel, chocolate, ethereal, nutty, sweet, and woody notes. Principal components analysis and Heatmap-cluster analysis of volatile metabolites grouped samples according to the fermentation time. Additionally, the total anthocyanin content declined during fermentation, and FRAP-TPC values showed a partial correlation. These results highlight the importance of fermentation for the improvement of the fine-flavor characteristics of cacao beans.

Leukemic infiltration of the ciliary body in a child with T-cell acute lymphoblastic leukemia.

A 14-year-old boy presented after 2 months of vision loss, redness, and pain in the right eye, initially treated as anterior uveitis with topical corticosteroids. He had a 1-year history of T-cell acute lymphoblastic leukemia, which had been in remission for 6 months. On examination, visual acuity in the right eye was light perception, with 4+ anterior chamber cells, pupillary membrane, and an intumescent cataract. Ultrasound biomicroscopy (UBM) revealed a ciliary body mass and capsular bag rupture. After consultation with his oncologist, he received 10 radiotherapy sessions. At 1 month, UBM showed resolution of the mass. After 1 year of remission, the patient underwent pars plana vitrectomy, pupillary membranectomy, and placement of a scleral-fixated intraocular lens. Thirty months after surgery, visual acuity was 20/25. Leukemic infiltration of the ciliary body is a rare manifestation of the disease that is often misdiagnosed as uveitis.

Empagliflozin and Dapagliflozin Improve Endothelial Function in Mexican Patients with Type 2 Diabetes Mellitus: A Double-Blind Clinical Trial.

AIM: To assess the acute effect of empagliflozin versus dapagliflozin administration on flow-mediated vasodilation in patients with type 2 diabetes mellitus. DESIGN: A double-blind clinical trial, at the Experimental and Clinical Therapeutics Institute, University Health Sciences Center, at the Universidad de Guadalajara, in inpatients with T2D according to the 2023 ADA criteria. METHODS: Thirty patients (15 males and 15 females), aged between 35 and 65 years, were included in this study, according to the 2023 ADA criteria. The eligible patients were randomly assigned to three groups: empagliflozin 25 mg once daily, dapagliflozin 10 mg once daily, or placebo once daily. Anthropometric parameters were taken using validated techniques. FMD was measured using a high-resolution semiautomatic ultrasound UNEX-EF 38G (UNEX Co., Ltd., Nagoya, Japan). Arterial tension was determined with the OMRON electronic digital sphygmomanometer (HEM 907 XL, Kyoto, Japan). RESULTS: The group of patients who received empagliflozin had a significantly lower baseline flow-mediated dilation (FMD) compared to the group receiving dapagliflozin (p = 0.017); at the end of this study, the empagliflozin group achieved a comparable FMD to the dapagliflozin group (p = 0.88). CONCLUSION: After the treatment period, the empagliflozin and dapagliflozin groups achieved similar FMD, suggesting a class effect.

Clinical Course and Outcomes of Autoimmune Versus Non-Autoimmune Surgically Induced Scleral Necrosis: A Multicentric Comparative Study.

BACKGROUND: To analyze the clinical course and outcomes of autoimmune vs. non-autoimmune surgically induced scleral necrosis (SISN). METHODS: Multicentric, retrospective, comparative cohort study. Eighty-two eyes of 70 patients with SISN were classified according to pathogenic mechanism into autoimmune vs. non-autoimmune. Main outcome measures included necrosis onset, type of surgery, associated systemic disease, visual acuity, and treatment were analysed in patients followed for ≥ 6 months. RESULTS: Forty-six (65.7%) patients were women, and the median age was 66 (range: 24-90) years. Most patients (82.9%) had unilateral disease. The median time between surgery and SISN onset was 58 (1-480) months. Thirty-one (37.8%) eyes were classified as autoimmune, and 51 (62.2%) as non-autoimmune SISN. Autoimmune SISN was associated with a shorter time between the surgical procedure and SISN onset than non-autoimmune cases (median of 26 vs. 60 months, p = 0.024). Also, autoimmune SISN was associated with cataract extraction (93.5% vs. 25.5%, p < 0.001), severe scleral inflammation (58.1% vs. 17.6%, p < 0.001), and higher incidence of ocular complications (67.7% vs. 33.3%, p = 0.002) than non-autoimmune cases. Remission was achieved with medical management alone in 44 (86.3%) eyes from the non-autoimmune and in 27 (87.1%) from the autoimmune group (p = 0.916). Surgical management was required in 11 (13.4%) eyes, including two requiring enucleations due to scleral perforation and phthisis bulbi. CONCLUSIONS: Eyes with autoimmune SISN had a higher rate of cataract surgery, severe scleral inflammation, and ocular complications. Early SISN diagnosis and appropriate management, based on clinical features and pathogenic mechanisms, are critical to avoid sight-threatening complications.

Creencias sobre prácticas de alimentación y obesidad de madres con hijos menores de 5 años del noroeste de México / Crenças sobre práticas de alimentação e obesidade entre mães com filhos menores de 5 anos de idade no noroeste do México / Beliefs about feeding practices and obesity among mothers with children under 5 years of age in northwestern Mexico

Introducción: Existe una tendencia mundial de incrementoen los índices de sobrepeso y obesidad en niños menoresde 5 años. Las creencias, percepciones y actitudes de lasmadres hacia las prácticas de alimentación y la obesidadtienen implicaciones directas sobre la salud del hijo.Objetivo: Explorar creencias sobre prácticas de alimentacióny obesidad infantil entre madres con hijos menores de cincoaños del noroeste de México.Metodología: Estudio cualitativo de aproximación etnográfica.Mediante un muestreo propositivo se realizaron nueve entrevistassemiestructuradas a mujeres que contaban con un promediode 12 años de educación.Resultados: Las creencias incluyeron inseguridad para asumirel rol de madre, una baja percepción de apoyo familiar ycreencias que no se alineaban con las recomendaciones dela lactancia materna exclusiva e introducción de alimentoscomplementarios. Además, estas tenían la creencia de que laobesidad no es un problema debido a la corta edad de sus hijos.Conclusiones: Existe una ambivalencia entre las creencias delas participantes y sus prácticas con relación a la alimentacióny la obesidad infantil. Es imperativo desarrollar estrategiasde educación y comunicación que proporcionen informaciónbasada en evidencia, de fácil acceso y disponible para madrescon la intención de prevenir problemas de nutrición durantela primera infancia.(AU)

Introduction: There is a worldwide trend of increasingrates of overweight and obesity in children under5 years of age. Mothers' beliefs, perceptions, andattitudes towards feeding practices and obesity havedirect implications on their children's health.Aim: To explore beliefs about feeding practices andchildhood obesity among mothers with children underfive years of age in northwestern Mexico.Methodology: Qualitative study with ethnographicapproach. Using purposive sampling, nine semi-structured interviews were conducted with womenwith an average of 12 years of education.Results: Beliefs included insecurity in assuming therole of mother, a low perception of family support, andbeliefs that were not aligned with the recommendations ofexclusive breastfeeding and introduction of complementary foods. In addition, these held the belief that obesity isnot a problem due to the young age of their children.Conclusions: There is ambivalence between theparticipants' beliefs and their practices regarding feedingand childhood obesity. It is imperative to developeducation and communication strategies that provideevidence-based information that is easily accessibleand available to mothers to prevent nutrition problemsduring early childhood.(AU)

Introdução: Há uma tendência mundial de aumentodas taxas de sobrepeso e obesidade em crianças commenos de 5 anos de idade. As crenças, percepções eatitudes das mães com relação às práticas alimentares eà obesidade têm implicações diretas na saúde infantil.Objetivo: explorar as crenças sobre práticas de alimentaçãoe obesidade infantil entre mães de crianças com menosde cinco anos de idade no noroeste do México.Metodologia: estudo qualitativo com uma abordagemetnográfica. Usando amostragem intencional, foramrealizadas nove entrevistas semiestruturadas commulheres com uma média de 12 anos de escolaridade.Resultados: As crenças incluíam insegurança em assumiro papel de mãe, baixa percepção de apoio familiar ecrenças que não se alinhavam com as recomendaçõesde amamentação exclusiva e introdução de alimentoscomplementares. Além disso, elas acreditavam quea obesidade não era um problema devido à poucaidade de seus filhos.Conclusões: Há uma ambivalência entre as crenças epráticas dos participantes com relação à alimentaçãoe à obesidade infantil. É imperativo desenvolverestratégias de educação e comunicação que forneçaminformações baseadas em evidências, facilmenteacessíveis e disponíveis para as mães, a fim de evitarproblemas de nutrição na primeira infância.(AU)

Efectos de Cinnamomum zeylanicum en niveles glucémicos en pacientes con diabetes tipo 2: ensayo clínico aleatorizado / Effects of Cinnamomum zeylanicum on glycemic levels in patients with type 2 diabetes: Randomized clinical trial

Objetivo: Evaluar el efecto del consumo de suplemento de Cinnamomum zeylanicum (canela) en los niveles glucémicos de adultos mexicanos con diabetes tipo 2. Métodos: Se realizó un ensayo clínico aleatorizado simple ciego con 30 pacientes >18 años con diabetes tipo 2, se aleatorizaron en los grupos: intervención y control; donde consumieron cápsulas con 2 gramos de C. zeylanicum o harina de trigo (placebo) diario por 12 semanas y se midieron variables antropométricas y bioquímicas (HbA1c, GPa, triglicéridos, colesterol total, HDL y LDL). Se utilizó el software IBM SPSS versión 23 y se aplicó la prueba T-Student y U-Mann Withney para muestras independientes (según el comportamiento de la variable) para las diferencias entre grupos, valores p<0.05 fueron considerados estadísticamente significativos. Resultados: No se observaron cambios significativos en HbA1c entre grupos (p>0.05). Sin embargo, post-tratamiento el grupo intervención disminuyó significativamente HbA1c al compararlo con su línea base (-0.41%, p=0.01) mientras que no se encontraron diferencias en el grupo control (+0.03%, p=0.64). No hubo diferencias significativas en variables antropométricas ni bioquímicas. Conclusiones: El consumo de 2 g de C. zeylanicum en mexicanos con diabetes tipo 2 no produjo cambios significativos entre grupos. Se sugieren nuevos estudios donde se evalúe el suplemento de canela con una muestra mayor. ClinicalTrials.gov; NCT04023539. (AU)

Objective: To evaluate the effect of Cinnamomum zeylanicum (cinnamon) supplement use on the glycemic levels of Mexican adults with type 2 diabetes. Methods: A single-blind randomized clinical trial was conducted with 30 patients over 18 years of age with type 2 diabetes. They were randomized into intervention and control groups where they took 2-gram capsules of Cinnamomum zeylanicum or wheat flour (placebo) daily for 12 weeks; then the anthropometric and biochemical variables HbA1c, FPG, triglycerides, total cholesterol, HDL and LDL were measured. IBM SPSS version 23 software was used and the Student's t-test and Mann-Whitney U test for independent samples (according to the behavior of the variable) were applied for differences between groups, p-values <0.05 were considered statistically significant. Results: No significant changes in HbA1c were seen between the two groups (p>0.05). However, post-treatment, the HbA1c value in the intervention group decreased significantly when compared to their baseline (-0.41%, p=0.01), while no differences were found in the control group (+0.03%, p=0.64). There were no significant differences in the anthropometric or biochemical variables. Conclusions: The consumption of 2 g of Cinnamomum zeylanicum in Mexican people with type 2 diabetes did not produce significant changes between the groups. New studies evaluating cinnamon supplementation on a larger sample size are suggested. ClinicalTrials.gov; NCT04023539. (AU)

Ansiedad, estrés y calidad de sueño asociados a COVID-19 en universitarios del noroeste de México / Anxiety, stress and sleep quality associated to COVID-19 in university students in northwestern Mexico

Resumen Objetivo: Identificar los niveles de ansiedad, estrés percibido y calidad del sueño en universitarios del noroeste de México durante la pandemia por COVID-19 y examinar su asociación con variables sociodemográficas y con preguntas relacionadas con el COVID-19. Materiales y métodos: Estudio descriptivo, correlacional y transversal, en una muestra no probabilística de 1691 estudiantes. Se aplicaron encuestas en línea por medio de Google Forms. Se utilizó la prueba Ji-cuadrado (X2), la correlación de Spearman y análisis de regresión logística multivariado, se contó con aprobación de comité de ética y consentimiento informado de los participantes. Resultados: El 38.4% de los estudiantes presentaron ansiedad moderada y 36.5% severa. Predominó un nivel moderado de estrés (50.1%) y mala calidad del sueño (65.8%). La variable sexo se asoció con ansiedad (X2 = 88.87, p < .001), estrés percibido (X2 = 72.34, p < .001) y mala calidad del sueño (X2 = 31.26, p < .001). La regresión logística determinó que los estudiantes cuyos ingresos familiares disminuyeron a causa de la pandemia presentaron mayor riesgo de ansiedad (OR = 1.67, p =.001), estrés (OR= 1.57, p =.011) y mala calidad del sueño (OR = 1.46). Conclusiones: Más de la mitad de los estudiantes universitarios que participaron en esta investigación presentaron algún nivel de ansiedad, estrés y mala calidad de sueño durante la pandemia por COVID-19, por lo anterior, se requiere el desarrollo de programas de intervención psicosocial de salud mental dirigidos a estudiantes universitarios.

Abstract Objective: Identify the levels of anxiety, perceived stress, and sleep quality in university students in northwestern Mexico during the COVID-19 pandemic and examine their association to sociodemographic variables and questions related to COVID-19. Materials and methods: Descriptive, correlational, cross-sectional study in a non-probabilistic sample of 1691 students. Online surveys were administered using Google Forms. The chi-square test (X2), Spearman's correlation and multivariate logistic regression analysis were used, with the approval of the ethics committee and informed consent of the participants. Results: 38.4% of the students presented moderate anxiety and 36.5% severe anxiety. Moderate level of stress (50.1%) and poor sleep quality (65.8%) predominated. The sex variable was associated to anxiety (X2 = 88.87, p < .001), perceived stress (X2 = 72.34, p < .001) and poor sleep quality (X2 = 31.26, p < .001). Logistic regression determined that students whose family income decreased because of the pandemic were at higher risk of experiencing anxiety (OR = 1.67, p =.001), stress (OR= 1.57, p =.011), and poor sleep quality (OR = 1.46). Conclusions: More than half of the university students who participated in this study presented some level of anxiety, stress and poor sleep quality during the COVID-19 pandemic. Therefore, the development of psychosocial mental health intervention programs aimed at university students is required.

Nivel de estrés y estrategias de afrontamiento utilizadas por estudiantes de la licenciatura en Enfermería / Level of Stress and Coping Strategies used by Students of the Bachelor of Nursing

Objetivo:Determinar la relación entre el nivel de estrés y las estrategias de afrontamiento utilizadas por estudiantes de la Licenciatura en Enfermería en Instituciones de Educación Superior (IES) de Ciudad Obregón, Sonora.Metodología:Estudio no experimental y correlacional; se empleó un muestreo probabilístico estratificado de 250 estudiantes, con edades entre los 18 y 46 años de edad. Los datos fueron recabados mediante un cuestionario de características sociodemográficas, el instrumento del nivel de estrés percibido y para medir afrontamiento el Brief COPE Inventory.Resultados:El 74.4% de la muestra fueron mujeres y el 25.6% hombres, ambos géneros exhibieron nivel de estrés moderado (78%), la estrategia de afrontamiento reportada con mayor frecuencia fue afrontamiento activo emocional. Se empleó la prueba no paramétrica chi-cuadrada de Pearson (χ2) para probar la existencia de asociación entre el nivel de estrés y las estrategias de afrontamiento (p= 0.67). Con base a los resultados de χ2 (p=.067) se realizó un análisis adicional separando las categorías de cada una de las variables de estudio, se utilizó la prueba de Pearson con la cual se encontró correlación significativa entre el nivel de estrés bajo y la estrategia afrontamiento activo emocional, (p=0.27) y entre nivel de estrés alto y estrategia de afrontamiento emocional por evitación (p=-.01).Conclusiones:Los niveles más altos de estrés lo manifiestan estudiantes que cursan solo materias teóricas. Se sugiere la implementación de intervenciones relacionadas al manejo adecuado del estrés. (AU)

Objetivo:Determinar la relación entre el nivel de estrés y las estrategias de afrontamiento utilizadas por estudiantes de la Licenciatura en Enfermería en Instituciones de Educación Superior (IES) de Ciudad Obregón, Sonora.Metodología:Estudio no experimental y correlacional; se empleó un muestreo probabilístico estratificado de 250 estudiantes, con edades entre los 18 y 46 años de edad. Los datos fueron recabados mediante un cuestionario de características sociodemográficas, el instrumento del nivel de estrés percibido y para medir afrontamiento el Brief COPE Inventory.Resultados:El 74.4% de la muestra fueron mujeres y el 25.6% hombres, ambos géneros exhibieron nivel de estrés moderado (78%), la estrategia de afrontamiento reportada con mayor frecuencia fue afrontamiento activo emocional. Se empleó la prueba no paramétrica chi-cuadrada de Pearson (χ2) para probar la existencia de asociación entre el nivel de estrés y las estrategias de afrontamiento (p= 0.67). Con base a los resultados de χ2 (p=.067) se realizó un análisis adicional separando las categorías de cada una de las variables de estudio, se utilizó la prueba de Pearson con la cual se encontró correlación significativa entre el nivel de estrés bajo y la estrategia afrontamiento activo emocional, (p=0.27) y entre nivel de estrés alto y estrategia de afrontamiento emocional por evitación (p=-.01).Conclusiones:Los niveles más altos de estrés lo manifiestan estudiantes que cursan solo materias teóricas. Se sugiere la implementación de intervenciones relacionadas al manejo adecuado del estrés. (AU)

Estrategias y limitaciones de la consejería en salud de enfermería: una revisión integradora de literatura / Strategies and limitations of applying health counseling in nursing: an integrative literature review

Resumen: Objetivo: Identificar ámbitos de aplicación de consejería en salud de enfermería y sus limitaciones. Materiales y Métodos: Revisión integradora de literatura; la búsqueda de los estudios se realizó en las bases de datos: Web of Science, Scopus, PubMed, ClinicalKey, OVID, CINAHL y Proquest. Se localizaron artículos publicados en el período del 2012 al 2021, en idiomas: español, inglés y portugués, que incluían en el título y/o resumen alguno de los siguientes descriptores: "Nursing health counseling", "Health promotion", "Patient centered care", "Nurse-Patient relationships", con el operador booleano "AND". Resultados: Once artículos cumplieron los criterios de inclusión y fueron analizados. Se identificaron hallazgos clave y se formularon categorías y temas a través de los estudios. En los resultados se presentan dos categorías a) estrategias para brindar consejería de salud en enfermería y b) limitaciones de la consejería de salud en enfermería. Conclusiones: Los ámbitos de aplicación de la consejería de salud en enfermería son amplios dentro de la atención primaria de salud, tanto para la promoción de la salud, como para el autocuidado de personas con diversas patologías; en cuanto a limitaciones es necesario contar con personal de enfermería capacitado.

Abstract: Objective: Identify the areas of application of nursing health counseling, and its limitations. Materials and Methods: Integrative literature review; the search of the studies was performed in the following databases: Web of Science, Scopus, PubMed, ClinicalKey, OVID, CINAHL, and Proquest. Articles that were published in the period from 2012 to 2021 were located in the following languages: Spanish, English, and Portuguese, which included in the title and/or abstract any of the following descriptors: "Nursing health counseling", "Health promotion", "Patient-Centered care", "Nurse-patient relationships", with the Boolean operator "AND". Results: Eleven articles met the inclusion criteria and were assessed. Key findings were identified and categorized into topics. In the results, two categories are shown: a) strategies to provide nursing health counseling and b) limitations of nursing health counseling. Conclusions: The application scope of nursing health counseling is broad within primary health care, both for the promotion of health and for the self-care of people with various pathologies; with respect to limitations, it is necessary to have trained nursing personnel.

Disincronía circadiana y su efecto sobre parámetros de síndrome metabólico en trabajadores: revisión integradora de la literatura / Circadian dyssynchrony and its effect on metabolic syndrome parameters in workers: an integrative literature review

INTRODUCCIÓN: La pérdida del ritmo circadiano causado por desórdenes del sueño es considerada un factor de riesgo importante para desarrollar enfermedades metabólicas como hiperglicemia y resistencia a la insulina. OBJETIVO: Analizar la literatura existente referente a estudios sobre disincronía circadiana en trabajadores y su influencia sobre parámetros antropométricos de síndrome metabólico de los mismos. MÉTODO: Se realizó una búsqueda en las bases de datos electrónicas EBSCO, Thompson Reuters, PubMed y Scopus, los términos de búsqueda seleccionados fueron: trabajo por turnos, melatonina, cortisol, síndrome metabólico, trabajo nocturno y ritmo circadiano, en los idiomas español e inglés, publicados de enero del 2015 a diciembre de 2018. La extracción se llevó a cabo utilizando un formulario prediseñado. RESULTADOS: La búsqueda en las bases de datos arrojó 5,953 artículos, posterior a la indagación y depuración de los mismos aplicando los criterios de elegibilidad, se obtuvieron 13 artículos los cuales se organizaron en dos dimensiones para su análisis, estas se denominaron a) trabajo en turnos y factores de riesgo metabólico y b) trabajo en turnos y ciclo circadiano. CONCLUSIONES: Es consistente la relación entre el trabajo nocturno o rotatorio, con diversas alteraciones metabólicas

INTRODUCTION: the loss of the circadian rhythm caused by sleep disorders is considered an important risk factor for developing metabolic diseases such as hyperglycemia and insulin resistance. AIM: to analyze the existing information regarding studies on circadian dyssynchrony in workers and its influence on anthropometric parameters of their metabolic syndrome. METHOD: The literature review was carried out by searching the EBSCO, Thompson Reuters, PubMed and Scopus electronic databases, the selected search terms were: shift work, melatonin, cortisol, metabolic syndrome, night work and circadian rhythm in the Spanish and English languages published from January 2015 to December 2018. The extraction was carried out using a predesigned form. RESULTS: The search in the databases yielded 5,953 articles, after the investigation and purification of the same ones applying the eligibility criteria, 13 articles were obtained which were organized in two dimensions for their analysis, these were called a) work in shifts and metabolic risk factors and b) shift work and the circadian cycle. CONCLUSIONS: The relationship between night or rotating work with various metabolic disorders is consistent

Riesgo de Esquizofrenia y Síndrome Deleción 22Q11. 2 / RIsk of schizophrenia and 22q11. 2 deletion syndrome

INTRODUCCIÓN. La deleción 22q11.2 es una alteración cromosómica muy frecuente, en la cual un 60% de los afectados presenta patologías neuropsiquiátricas. Determinar si existe asociación entre el síndrome de deleción 22q11.2 (SD22q11.2) y patologías como la esquizofrenia (EQZ), ofrece una oportunidad para la intervención temprana, y seguimiento de personas con este síndrome. OBJETIVO. El objetivo del presente trabajo es determinar si existe mayor riesgo de EQZ en pacientes con síndrome deleción 22q11.2. MÉTODOS. Se realizó una búsqueda bibliográfica sistemática de publicaciones con fecha de 1990 a 2020. Las búsquedas se realizaron en PubMed y en la base de datos Cochrane. En total, se evaluaron 19 estudios, de los que se consideraron elegibles diez publicaciones para el análisis, lo que corresponde a 824 participantes. RESULTADOS. El riesgo de presentar EQZ en un individuo con SD22q11.2 es de 20-25%, en comparación al 1% de la población general. CONCLUSIONES. El riesgo para un individuo con SD22q11.2 de presentar EQZ se encuentra bien establecido. Considerar este riesgo podría ayudar a un adecuado seguimiento y una intervención temprana.

INTRODUCTION. 22q11.2 deletion syndrome is a very common chromosomal abnormality, in which 60% of those affected have neuropsychiatric disorders. Determining if there is an association between 22q11.2 deletion syndrome (22q11.2DS) and disorders such as schizophrenia (SCZ) offers an opportunity for early intervention and follow-up of people with this syndrome. OBJECTIVE. The objective of this study is to determine if there is a greater risk of SCZ in patients with 22q11.2 deletion syndrome. METHODS. A systematic review was performed for publications dated 1990 to 2020. The strategy was to search in PubMed and Cochrane databases for specific MeSH terms. In total, 19 studies were reviewed, of which 10 publications were eligible for analysis, corresponding to 824 participants. RESULTS. The risk of presenting SCZ in an individual with 22q11.2DS is 20-25%, compared to 1% in the general population.CONCLUSIONS. The risk of presenting SCZ in an individual with 22q11.2DS is well established. Considering this risk could help with adequate follow-up and early intervention.

Trisomía 9, trisomía 13 y trisomía 18: resultados del análisis citogenético prenatal, Hospital Clínico Universidad de Chile, años 2000-2017 / Trisomy 9, trisomy 13 and trisomy 18: results of the prenatal cytogenical analysis, Hospital Clínico Universidad de Chile, years 2000-2017

INTRODUCCIÓN: En Chile, la norma técnica de la Ley N° 21.030 de 2017 considera tres aneuploidías como letales; las trisomías 9, 13 y 18, cuyo diagnóstico se confirma con un cariograma. No existe a la fecha registro nacional de frecuencia prenatal de estas patologías. OBJETIVO: Determinar la frecuencia de trisomías 9, 13 y 18 en los estudios citogenéticos prenatales en muestras de células obtenidas con amniocentesis y cordocentesis, procesados en el Laboratorio de Citogenética del Hospital Clínico Universidad de Chile. MATERIALES Y MÉTODOS: Estudio descriptivo y retrospectivo de los resultados de cariograma de líquido amniótico (LA) y sangre fetal (SF), procesados desde enero de 2000 a diciembre de 2017. RESULTADOS: Se incluyeron 2.305 muestras (402 de SF y 1.903 de LA), de ellas 442 (19%) fueron trisomías letales (TL), dentro de ellas fueron TL libres 416 (95%), TL estructurales 15 (2,7%) y mosaicos 11 (2,3%). La trisomía 18 fue en ambos tipos de muestra la más frecuente (73,5%), seguida de trisomía 13 (24,2%) y trisomía 9 (2,3%). Se desglosan resultados conforme al tipo de TL, muestra, motivo de derivación, edad materna y edad gestacional. CONCLUSIONES: El cariograma confirma el diagnóstico de aneuploidías y aporta datos relevantes para el consejo genético. La cromosomopatía letal más frecuente fue la trisomía 18. Se observó que uno de cada cinco cariogramas referidos por anomalías congénitas y/o marcadores de aneuploidía revelaban una TL.

INTRODUCTION: In Chile, the technical standard of Law No. 21,030 of 2017 considers three aneuploidies as lethal; trisomies 9, 13 and 18, whose diagnosis is confirmed with a Karyotype. To date there is not a national registry of prenatal frequency of these pathologies. OBJECTIVE: To determine the frequency of trisomies 9, 13 and 18 in prenatal cytogenetic studies in samples of cells obtained with amniocentesis and cordocentesis, processed in the Cytogenetics Laboratory of the Universidad de Chile Clinical Hospital. MATERIALS AND METHODS: Descriptive and retrospective study of the results of karyotypes of amniotic fluid (LA) and fetal blood (SF) processed from January 2000 to December 2017. Results: 2,305 samples (402 of SF and 1,903 of LA) were included, of which 438 (19%) were lethal trisomies (TL), corresponding to free TL 416 (95%), structural TL 12 (2,7%) and mosaics 10 (2.3%). Trisomy 18 was the most frequent in both types of sample (73,5 %), followed by trisomy 13 (24,2%) and trisomy 9 (2.3%). RESULTS are shown according to the type of TL, sample, reason for referral, maternal age and gestational age. CONCLUSIONS: The karyotype confirms the diagnosis of aneuploidies and provides relevant data for genetic counseling. The most frequent lethal chromosomopathy was trisomy 18. It was observed that one in five karyotypes referred for congenital anomalies and / or aneuploidy markers revealed a TL.

Características de la publicación científica de enfermería en México: período 2010-2016 / Characteristics of the scientific publication of nursing in México: 2010-2016 period

Introducción: la difusión del conocimiento es fundamental para el desarrollo de la ciencia. En México existen pocos estudios que describan las características de la producción científica de enfermería. Objetivo: describir las características de la publicación de enfermería en México durante el período 2010-2016. Metodología: estudio cuantitativo, descriptivo y retrospectivo. Se realizó una búsqueda de artículos en las bases de datos EBSCO Host, Scopus, Scielo, Medigraphic, Redalyc, Dialnet, PubMed y Periódica. Se analizaron mediante esta- dística descriptiva. Resultados: se publicaron anualmente 61 artículos (DE = 2.01), en su mayor parte en revistas mexicanas (78.7%). La temática más frecuente es el cuidado o la atención de enfermería (11.0%); el 67.5% correspondió a estudios cuantitativos y el 13.6% utiliza una teoría de enfermería. Conclusiones: la caracterización de las publicaciones de enfermería nacionales permite identificar necesidades en investigación, como emplear metodologías que provean mayor grado de evidencia científica y establecer líneas de investigación prioritarias mediante teorías disciplinares.

Introduction: The diffusion of knowledge is fundamental for the development of a science. In Mexico there are few studies that present the characteristics of the scientific production of nursing. Objective: To describe the characteristics of the nursing publication in Mexico during the period 2010-2016. Methods: Quantitative, descriptive and retrospective study. A search of articles was carried out in the EBSCO Host, Scopus, Scielo, Medigraphic, Redalyc, Dialnet, PubMed and Periodic databases. They were analyzed by descriptive statistics. Results: 61 articles were published annually (SD = 2.01), mostly in Mexican journals (78.7%).The most frequent theme is nursing care and / or care (11.0%); 67.5% were quantitative studies and 13.6% used a nursing theory. Conclusions: The characterization of nursing publications at the national level allows us to identify research needs, such as entering into methodologies that provide a higher level of scientific evidence and establish priority research lines, using disciplinary theories.

Síndrome de deficiencia de GLUT-1 / GLUT-1 deficiency síndrome

No disponible

Investigación en enfermería en unidad de cuidado intensivo del adulto: una revisión de literatura / Research in nursing in adult intensive careunits: a literatura review

OBJETIVO: Identificar cual es la tendencia en investigación desarrollada por enfermeras en las unidades de cuidado intensivo de adultos en diferentes contextos. METODOLOGÍA: Revisión de literatura, que pretende dar respuesta a la siguiente pregunta de investigación ¿Cuál es la tendencia en investigación desarrollada por las enfermeras en las unidades de cuidado intensivo, en diferentes contextos? La búsqueda de los artículos se realizó en las siguientes bases de datos informatizadas: Web of Science, Scopus, PubMed, CINAHL, OVID y Proquest. Los criterios de selección fueron artículos disponibles a texto completo, en español, publicados entre enero de 2010 a noviembre del 2016, que incluyeran en el título y/o resumen los términos de búsqueda "enfermería", "unidad de cuidados intensivos" y "cuidado". Con el operador boolenano "AND". Se incluyeron artículos de investigación cualitativa y/o cuantitativa. RESULTADOS: la búsqueda arrojó 14 artículos. El análisis de los diversos artículos seleccionados permitió agrupar la información en dos dimensiones, las cuales se denominan 1) contribución a la gestión del cuidado en la unidad de cuidados intensivos y 2) contribución a la disciplina y práctica especializada de unidad de cuidados intensivos. CONCLUSIONES: Las tendencias identificadas en investigación desarrollada por enfermeras en las unidades de cuidado intensivo, contribuyen a fortalecer la gestión del cuidado, disciplina y práctica de enfermería.

OBJECTIVE: To identify available articles on nursing in intensive care unitsof adults, as well as research trends published nationally and internationally related to the subject. METHODOLOGY: An integrative literature review, which aims to answer the following research question. What are the recent publications on nursing in intensive care? The search for the articles was made in the following databases: Web of Science, Scopus, PubMed, CINAHL, OVID y Proquest. The selection criteria were articles available in full text, in Spanish, published between January 2010 and November 2016, including in the title and / or summary the search terms "nursing", "intensive care unit" ", "nursing care". RESULTS: The search yielded 14 articles. The analysis of the articles selected allowed to group the information into two dimensions, which are called 1) contribution to care management in the intensive care unit and 2) contribution to the discipline and specialized practice of the intensive care unit. CONCLUSIONS: The tendencies identified in research developed by nurses of intensive care units, contribute to strengthen the management of nursing care, discipline and practice.

Serie de Casos: Síndrome de Parry Romberg, Resolución Quirúrgica / Case Series: Parry Romberg Syndrome, Surgical Resolution

INTRODUCCIÓN: El síndrome de Parry Romberg o atrofia hemifacial progresiva es una patología caracterizada por causar atrofia facial unilateral con afectación de piel, tejido celular subcutáneo y músculo. Su prevalencia mundial es de 1/700 000, tiene predominio por el sexo femenino con una proporción mujer ­ hombre de 3:2. Clínicamente se manifiesta como una esclerodermia lineal en golpe de sable, y afecta con mayor frecuencia a hemicara izquierda. El tratamiento es de tipo quirúrgico e incluye técnicas como injertos, colgajos o prótesis. CASO CLÍNICO: A continuación se presenta una serie de casos que incluye a tres pacientes que consultaron por alteraciones de la anatomía y el desarrollo facial; quienes posterior a un examen físico minucioso y a la realización de exámenes de imagen, fueron diagnosticados de síndrome de Parry Romberg. EVOLUCIÓN: En todos los casos el tratamiento fue quirúrgico; optándose por la colocación de un injerto dermograso en la zona afectada, el mismo que fue obtenido de la cavidad abdominal. La evolución clínica y la adherencia del injerto fue satisfactoria y sin complicaciones. CONCLUSIÓN: Los resultados obtenidos de la colocación de injertos dermograsos para el tratamiento de la atrofia hemifacial progresiva fueron excelentes a corto, mediano y largo plazo.(au)

BACKGROUND: Parry Romberg syndrome or progressive hemifacial atrophy is an entity characterized by unilateral facial atrophy with involvement of skin, subcutaneous tissue and muscle. Its worldwide prevalence is 1/700 000, with a female - male ratio of 3:2. Clinically it manifests as linear scleroderma and most frequently affects the left side of the face. The treatment is surgery and includes techniques such as grafts, flaps or prostheses. CASE REPORT: The following is a case series that includes three patients, who consulted for anatomic and developmental alterations of the face; who after a meticoluos physical examination and imaging tests were diagnosed with Parry Romberg syndrome. EVOLUTION: In all cases, the treatment was surgery; opting for the placement of a skin graft in the affected area, which was obtained from the abdominal cavity. The clinical evolution and adherence of the graft was satisfactory and without complications. CONCLUSION: The results obtained from the placement of skin graft as the treatment of progressive hemifacial atrophy were excellent in short, medium and long term.(au)