Detalles de la búsqueda
1.
Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression.
Mol Cancer
; 23(1): 49, 2024 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38459596
2.
Direct chemical induction of hepatocyte-like cells with capacity for liver repopulation.
Hepatology
; 77(5): 1550-1565, 2023 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35881538
3.
Insights into Inhalation Drug Disposition: The Roles of Pulmonary Drug-Metabolizing Enzymes and Transporters.
Int J Mol Sci
; 25(9)2024 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38731891
4.
Prediction of Human Pharmacokinetics of E0703, a Novel Radioprotective Agent, Using Physiologically Based Pharmacokinetic Modeling and an Interspecies Extrapolation Approach.
Int J Mol Sci
; 25(5)2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38474292
5.
Dissolving microneedles loaded with nimodipine for prevention of sleep disorders at a high altitude.
Pharm Dev Technol
; : 1-14, 2024 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38626316
6.
Alternation of Organ-Specific Exposure in LPS-Induced Pneumonia Mice after the Inhalation of Tetrandrine Is Governed by Metabolizing Enzyme Suppression and Lysosomal Trapping.
Int J Mol Sci
; 23(21)2022 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-36361734
7.
Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach.
Int J Mol Sci
; 23(9)2022 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35562875
8.
Assessment and Confirmation of Species Difference in Nonlinear Pharmacokinetics of Atipamezole with Physiologically Based Pharmacokinetic Modeling.
Drug Metab Dispos
; 48(1): 41-51, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31699808
9.
PEGylated leuprolide with improved pharmacokinetic properties.
Bioorg Med Chem
; 28(4): 115306, 2020 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31926774
10.
N-Quinary heterocycle-4-sulphamoylbenzamides exert anti-hypoxic effects as dual inhibitors of carbonic anhydrases I/II.
Bioorg Chem
; 100: 103931, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32450385
11.
New insights into the vancomycin-induced nephrotoxicity using in vitro metabolomics combined with physiologically based pharmacokinetic modeling.
J Appl Toxicol
; 40(7): 897-907, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32079046
12.
Quadrupole Orbitrap Mass Spectrometer-Based Metabonomic Elucidation of Influences of Short-Term Di(2-ethylhexyl) phthalate Exposure on Cardiac Metabolism in Male Mice.
Chem Res Toxicol
; 31(11): 1185-1194, 2018 11 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30284816
13.
Zero-Order Release of Gossypol Improves Its Antifertility Effect and Reduces Its Side Effects Simultaneously.
Biomacromolecules
; 19(6): 1918-1925, 2018 06 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29355309
14.
Separation and simultaneous quantification of nine furanocoumarins from Radix Angelicae dahuricae using liquid chromatography with tandem mass spectrometry for bioavailability determination in rats.
J Sep Sci
; 38(24): 4216-24, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26496866
15.
P-Glycoprotein (ABCB1) limits the brain distribution of YQA-14, a novel dopamine D3 receptor antagonist.
Chem Pharm Bull (Tokyo)
; 63(7): 512-8, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26133067
16.
[The evaluation of efflux transporter model based on RNA interference technology in vitro].
Yao Xue Xue Bao
; 50(9): 1122-7, 2015 Sep.
Artículo
en Zh
| MEDLINE | ID: mdl-26757548
17.
PQ-69, a novel and selective adenosine A1 receptor antagonist with inverse agonist activity.
Purinergic Signal
; 10(4): 619-29, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25248972
18.
Simultaneous quantification of L-tetrahydropalmatine and its urine metabolites by ultra high performance liquid chromatography with tandem mass spectrometry.
J Sep Sci
; 37(6): 696-703, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24453165
19.
Characterization of preclinical in vitro and in vivo ADME properties and prediction of human PK using a physiologically based pharmacokinetic model for YQA-14, a new dopamine D3 receptor antagonist candidate for treatment of drug addiction.
Biopharm Drug Dispos
; 35(5): 296-307, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24647883
20.
[Investigation of metabolic kinetics and reaction phenotyping of ligustrazin by using liver microsomes and recombinant human enzymes].
Yao Xue Xue Bao
; 49(3): 374-9, 2014 Mar.
Artículo
en Zh
| MEDLINE | ID: mdl-24961110