1.
Org Lett
; 25(17): 3094-3098, 2023 May 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37087758
RESUMEN
We report a four-component ring-opening reaction of pyrroles via C-N bond cleavage. In this process, elemental sulfur is used as the sulfur source of thiazole and thioamide and the reductant of olefin. A series of benzothiazoles functionalized with thiopropionamides at the C2 position were synthesized using this method. A plausible reaction mechanism is proposed based on the concise control experiments.