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1.
Epidemiol Infect ; 149: e111, 2021 04 27.
Artículo en Inglés | MEDLINE | ID: mdl-33902767

RESUMEN

The explosive outbreak of COVID-19 led to a shortage of medical resources, including isolation rooms in hospitals, healthcare workers (HCWs) and personal protective equipment. Here, we constructed a new model, non-contact community treatment centres to monitor and quarantine asymptomatic and mildly symptomatic COVID-19 patients who recorded their own vital signs using a smartphone application. This new model in Korea is useful to overcome shortages of medical resources and to minimise the risk of infection transmission to HCWs.


Asunto(s)
COVID-19/terapia , Arquitectura y Construcción de Hospitales/métodos , Hospitales Comunitarios/métodos , Adulto , Femenino , Hospitales Comunitarios/clasificación , Humanos , Masculino , Persona de Mediana Edad , Cuarentena/métodos , República de Corea , Unidades de Autocuidado
2.
Hum Mol Genet ; 26(10): 1966-1978, 2017 05 15.
Artículo en Inglés | MEDLINE | ID: mdl-28334935

RESUMEN

Genetic variants contribute to normal variation of iron-related traits and may also cause clinical syndromes of iron deficiency or excess. Iron overload and deficiency can adversely affect human health. For example, elevated iron storage is associated with increased diabetes risk, although mechanisms are still being investigated. We conducted the first genome-wide association study of serum iron, total iron binding capacity (TIBC), transferrin saturation, and ferritin in a Hispanic/Latino cohort, the Hispanic Community Health Study/Study of Latinos (>12 000 participants) and also assessed the generalization of previously known loci to this population. We then evaluated whether iron-associated variants were associated with diabetes and glycemic traits. We found evidence for a novel association between TIBC and a variant near the gene for protein phosphatase 1, regulatory subunit 3B (PPP1R3B; rs4841132, ß = -0.116, P = 7.44 × 10-8). The effect strengthened when iron deficient individuals were excluded (ß = -0.121, P = 4.78 × 10-9). Ten of sixteen variants previously associated with iron traits generalized to HCHS/SOL, including variants at the transferrin (TF), hemochromatosis (HFE), fatty acid desaturase 2 (FADS2)/myelin regulatory factor (MYRF), transmembrane protease, serine 6 (TMPRSS6), transferrin receptor (TFR2), N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2), ABO blood group (ABO), and GRB2 associated binding protein 3 (GAB3) loci. In examining iron variant associations with glucose homeostasis, an iron-raising variant of TMPRSS6 was associated with lower HbA1c levels (P = 8.66 × 10-10). This association was attenuated upon adjustment for iron measures. In contrast, the iron-raising allele of PPP1R3B was associated with higher levels of fasting glucose (P = 7.70 × 10-7) and fasting insulin (P = 4.79 × 10-6), but these associations were not attenuated upon adjustment for TIBC-so iron is not likely a mediator. These results provide new genetic information on iron traits and their connection with glucose homeostasis.


Asunto(s)
Glucosa/genética , Glucosa/metabolismo , Hierro/metabolismo , Adulto , Anemia Ferropénica/sangre , Antígenos CD , Glucemia/metabolismo , Diabetes Mellitus/genética , Diabetes Mellitus/metabolismo , Ayuno , Femenino , Ferritinas/análisis , Ferritinas/sangre , Ferritinas/metabolismo , Estudios de Asociación Genética/métodos , Variación Genética/genética , Estudio de Asociación del Genoma Completo , Genómica , Hemocromatosis/genética , Hispánicos o Latinos/genética , Hospitales Comunitarios/métodos , Humanos , Insulina/metabolismo , Hierro/sangre , Masculino , Proteínas de la Membrana/genética , Proteínas de la Membrana/metabolismo , Persona de Mediana Edad , Fenotipo , Polimorfismo de Nucleótido Simple/genética , Receptores de Transferrina/genética , Factores de Riesgo , Serina Endopeptidasas/genética , Serina Endopeptidasas/metabolismo , Transferrina/análisis , Transferrina/metabolismo
3.
J Infect Chemother ; 25(11): 860-865, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31109751

RESUMEN

BACKGROUND: Although tertiary hospitals have successfully introduced ASPs by antimicrobial stewardship teams, lots of community hospitals without pediatric infectious disease specialists have difficulty implementing ASP. We present a successful implementation of simple and feasible NICU antimicrobial stewardship program in a Japanese community hospital. METHOD: We developed a protocol of antimicrobial treatment in our NICU department and have implemented the protocol from September 2017. The protocol consists of start and stop of criteria antimicrobial treatment, weekend report of blood culture result from microbiology department and stopping ordering antimicrobials beforehand for the next day. We compared days of therapy (DOT) during the post-implementation period (September 2017 to August 2018) with that of pre-implementation period (March 2013 to August 2017). RESULT: In pre- and post-ASP implementation periods, 913 and 194 patients were analyzed. DOT was 175.1 and 41.6/1000 patient-days, respectively (p < 0.001) with 76.2% reduction. The percentage of neonates who had any antimicrobials and the percentage of prolonged antimicrobial treatments among neonates who had any antimicrobials decreased significantly (55.3% vs 20.6%, p < 0.001 and 65.0% vs 32.5%, p < 0.001). The protocol compliance rates were also significantly different (55.4% vs 95.4%; p < 0.001). The methicillin-resistant rate of S.aureus rates were significantly reduced in post-ASP period (31.1% vs 12.9%; p = 0.002). CONCLUSION: This ASP program was easily implemented in a NICU department of a community hospital and significantly reduced antimicrobial prescription. This kind of simple protocol may be successfully scaled-up in resource limited community hospitals without no pediatric infectious disease specialists or antimicrobial stewardship team.


Asunto(s)
Antibacterianos/uso terapéutico , Programas de Optimización del Uso de los Antimicrobianos/métodos , Enfermedades Transmisibles/tratamiento farmacológico , Staphylococcus aureus Resistente a Meticilina/efectos de los fármacos , Infecciones Estafilocócicas/tratamiento farmacológico , Adhesión a Directriz , Hospitales Comunitarios/métodos , Humanos , Unidades de Cuidado Intensivo Neonatal , Japón , Estudios Retrospectivos , Centros de Atención Terciaria
4.
BMC Geriatr ; 19(1): 288, 2019 10 25.
Artículo en Inglés | MEDLINE | ID: mdl-31653204

RESUMEN

BACKGROUND: As the population ages, older hospitalized patients are at increased risk for hospital-acquired morbidity. The Mobilization of Vulnerable Elders (MOVE) program is an evidence-informed early mobilization intervention that was previously evaluated in Ontario, Canada. The program was effective at improving mobilization rates and decreasing length of stay in academic hospitals. The aim of this study was to scale-up the program and conduct a replication study evaluating the impact of the evidence-informed mobilization intervention on various units in community hospitals within a different Canadian province. METHODS: The MOVE program was tailored to the local context at four community hospitals in Alberta, Canada. The study population was patients aged 65 years and older who were admitted to medicine, surgery, rehabilitation and intensive care units between July 2015 and July 2016. The primary outcome was patient mobilization measured by conducting visual audits twice a week, three times a day. The secondary outcomes included hospital length of stay obtained from hospital administrative data, and perceptions of the intervention assessed through a qualitative assessment. Using an interrupted time series design, the intervention was evaluated over three time periods (pre-intervention, during, and post-intervention). RESULTS: A total of 3601 patients [mean age 80.1 years (SD = 8.4 years)] were included in the overall analysis. There was a significant increase in mobilization at the end of the intervention period compared to pre-intervention, with 6% more patients out of bed (95% confidence interval (CI) 1, 11; p-value = 0.0173). A decreasing trend in median length of stay was observed, where patients on average stayed an estimated 3.59 fewer days (95%CI -15.06, 7.88) during the intervention compared to pre-intervention period. CONCLUSIONS: MOVE is a low-cost, effective and adaptable intervention that improves mobilization in older hospitalized patients. This intervention has been replicated and scaled up across various units and hospital settings.


Asunto(s)
Ambulación Precoz/métodos , Hospitalización , Hospitales Comunitarios/métodos , Análisis de Series de Tiempo Interrumpido/métodos , Anciano , Anciano de 80 o más Años , Alberta/epidemiología , Femenino , Hospitalización/tendencias , Hospitales Comunitarios/tendencias , Humanos , Análisis de Series de Tiempo Interrumpido/tendencias , Tiempo de Internación/tendencias , Masculino
5.
Health Care Manage Rev ; 44(3): 274-284, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-28915164

RESUMEN

BACKGROUND: Community orientation refers to hospitals' efforts to assess and meet the health needs of the local population. Variations in the number of community orientation-related activities offered by hospitals may be attributed to differences in organizational and environmental characteristics. Therefore, hospitals have to strategically respond to these internal and external constraints to improve community health. Understanding the facilitators and barriers of hospital community orientation is important to health care managers facing pressure from the external environment to meet the expectations of the community as well as Affordable Care Act guidelines. PURPOSE: The purpose of this study was to examine the organizational and environmental factors that promote or impede hospital community orientation. METHODOLOGY: A multivariate regression with random effects was conducted using data from the American Hospital Association Annual Survey from 2007 to 2010 and county level data from the Area Health Resource Files. FINDINGS: Not-for-profit, system-affiliated, network-affiliated, and larger hospitals have a higher degree of community orientation. In addition, the percentage of the county residents under the age of 65 years with health insurance and hospitals in states with certificate-of-need laws were also positively related to the degree of community orientation. During the study period, it appears that organizational factors mattered more in determining the degree of community orientation. PRACTICE IMPLICATIONS: Overall, a better understanding of the factors that influence community orientation can assist hospital administrators and policymakers in stimulating the hospital's role in improving population health and its responsiveness to community health needs. These efforts may occur by building interorganizational relationships or by incentivizing those hospitals that are least likely to be community oriented.


Asunto(s)
Relaciones Comunidad-Institución , Administración Hospitalaria , Administración Hospitalaria/métodos , Administración Hospitalaria/estadística & datos numéricos , Hospitales/estadística & datos numéricos , Hospitales Comunitarios/métodos , Hospitales Comunitarios/organización & administración , Hospitales Comunitarios/estadística & datos numéricos , Humanos , Propiedad/organización & administración , Propiedad/estadística & datos numéricos , Patient Protection and Affordable Care Act , Salud Pública , Encuestas y Cuestionarios , Estados Unidos
6.
J Public Health Manag Pract ; 25(4): E1-E8, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31136519

RESUMEN

CONTEXT: As of March 23, 2012, the Internal Revenue Service (IRS) requires tax-exempt hospitals to conduct Community Health Needs Assessment (CHNA) every 3 years to incentivize hospitals to provide programs responsive to the health needs of their communities. OBJECTIVE: To examine the distribution and variation in community benefit spending among North Carolina's tax-exempt hospitals 2 years after completing their first IRS-mandated CHNA. DESIGN: Cross-sectional study using secondary analysis of published community benefit reports. Community benefit was categorized on the basis of North Carolina Hospital Association's community benefit reporting guidelines. Multiple regression analysis using generalized linear model was used to examine the variation in community benefit spending among study hospitals considering differences in hospital-level and community characteristics. SETTING: Fifty-three private, nonprofit hospitals across North Carolina. MAIN OUTCOME MEASURE: Dollar expenditures as a percentage of operating expenses of the 2 categories of community benefit spending: patient care financial assistance and community health programs. RESULTS: Study hospitals' aggregate community benefit spending was $2.6 billion, 85% of which was in the form of patient care financial assistance, with only 0.7% of total spending allocated to community-building activities such as affordable housing, economic development, and environmental improvements. On average, the study hospitals' community benefit spending was equivalent to 14.6% of operating expenses. Hospitals with 300 or more beds provided significantly higher investments in community health programs as a percentage of their operating expenses than hospitals with 101 to 299 beds (P = .03) or hospitals with 100 or fewer beds (P = .04). Access to care was not associated with patient care financial assistance (P = .81) or community health programs expenditures (P = .94). CONCLUSIONS: The study hospitals direct most of their community benefit expenditures to patient care financial assistance (individual welfare) rather than population health improvement initiatives, with virtually no investments in community-building activities that address socioeconomic determinants of health.


Asunto(s)
Hospitales Comunitarios/economía , Evaluación de Necesidades/economía , Servicios de Salud Comunitaria/economía , Servicios de Salud Comunitaria/métodos , Servicios de Salud Comunitaria/tendencias , Estudios Transversales , Administración Financiera de Hospitales/métodos , Administración Financiera de Hospitales/estadística & datos numéricos , Administración Financiera de Hospitales/tendencias , Hospitales Comunitarios/métodos , Hospitales Comunitarios/organización & administración , Humanos , Evaluación de Necesidades/estadística & datos numéricos , North Carolina , Exención de Impuesto/tendencias
7.
Artículo en Inglés | MEDLINE | ID: mdl-30150472

RESUMEN

In community hospitals, antimicrobial stewardship team notification of rapid diagnostic testing (RDT) results may not be feasible. A retrospective quasi-experimental study was conducted evaluating 252 adult inpatients with blood cultures positive for Gram-positive cocci in clusters (pre-RDT, n = 143; post-RDT, n = 109). The median time to appropriate therapy was significantly shorter in the post-RDT group (15 versus 0 h, P < 0.001), and the mean length of stay for patients with coagulase-negative staphylococcus was significantly shorter (10.5 versus 7.7 days; P = 0.015).


Asunto(s)
Infecciones por Bacterias Grampositivas/diagnóstico , Cocos Grampositivos/aislamiento & purificación , Adulto , Programas de Optimización del Uso de los Antimicrobianos/métodos , Bacteriemia/sangre , Bacteriemia/diagnóstico , Bacteriemia/metabolismo , Bacteriemia/microbiología , Cultivo de Sangre/métodos , Coagulasa/metabolismo , Femenino , Infecciones por Bacterias Grampositivas/sangre , Infecciones por Bacterias Grampositivas/metabolismo , Infecciones por Bacterias Grampositivas/microbiología , Hospitales Comunitarios/métodos , Hospitales de Enseñanza/métodos , Humanos , Tiempo de Internación , Masculino , Estudios Retrospectivos , Infecciones Estafilocócicas/sangre , Infecciones Estafilocócicas/diagnóstico , Infecciones Estafilocócicas/metabolismo , Infecciones Estafilocócicas/microbiología , Staphylococcus/aislamiento & purificación
8.
J Public Health Manag Pract ; 24(5): 417-423, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29240614

RESUMEN

CONTEXT: Many hospitals in the United States are exploring greater investment in community health activities that address upstream causes of poor health. OBJECTIVE: Develop and apply a measure to categorize and estimate the potential impact of hospitals' community health activities on population health and equity. DESIGN, SETTING, AND PARTICIPANTS: We propose a scale of potential impact on population health and equity, based on the cliff analogy developed by Jones and colleagues. The scale is applied to the 317 activities reported in the community health needs assessment implementation plan reports of 23 health care organizations in the Minneapolis-St Paul, Minnesota, metropolitan area in 2015. MAIN OUTCOME MEASURE: Using a 5-point ordinal scale, we assigned a score of potential impact on population health and equity to each community health activity. RESULTS: A majority (50.2%) of health care organizations' community health activities are classified as addressing social determinants of health (level 4 on the 5-point scale), though very few (5.4%) address structural causes of health equity (level 5 on the 5-point scale). Activities that score highest on potential impact fall into the topic categories of "community health and connectedness" and "healthy lifestyles and wellness." Lower-scoring activities focus on sick or at-risk individuals, such as the topic category of "chronic disease prevention, management, and screening." Health care organizations in the Minneapolis-St Paul metropolitan area vary substantially in the potential impact of their aggregated community health activities. CONCLUSIONS: Hospitals can be significant contributors to investment in upstream community health programs. This article provides a scale that can be used not only by hospitals but by other health care and public health organizations to better align their community health strategies, investments, and partnerships with programming and policies that address the foundational causes of population health and equity within the communities they serve.


Asunto(s)
Equidad en Salud/normas , Hospitales Comunitarios/normas , Salud Pública/normas , Equidad en Salud/estadística & datos numéricos , Hospitales Comunitarios/métodos , Humanos , Minnesota , Vigilancia de la Población/métodos , Evaluación de Programas y Proyectos de Salud/métodos , Salud Pública/métodos
9.
Neonatal Netw ; 37(3): 155-163, 2018 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-29789056

RESUMEN

Perinatal hypoxia is a devastating event before, during, or immediately after birth that deprives an infant's vital organs of oxygen. This injury at birth often requires a complex resuscitation and increases the newborn's risk of hypoxic-ischemic encephalopathy (HIE). The resuscitation team in a community hospital nursery may have less experience with complex resuscitation and post-resuscitation care of this infant than a NICU. This article provides the neonatal nurse in a Level I or Level II nursery with information about resuscitation and post-resuscitation care of an infant at risk of HIE while awaiting transport to a NICU for therapeutic cooling. The article describes the infant at risk for HIE, discusses pathophysiology and treatment of HIE, and lists essential components of post-resuscitation care while awaiting transport to an NICU, the importance of communication with the receiving NICU, and strategies for supporting the family.


Asunto(s)
Asfixia Neonatal , Hipotermia Inducida/métodos , Hipoxia-Isquemia Encefálica , Transferencia de Pacientes/métodos , Resucitación/métodos , Cuidados Posteriores/métodos , Asfixia Neonatal/complicaciones , Asfixia Neonatal/fisiopatología , Hospitales Comunitarios/métodos , Humanos , Hipoxia-Isquemia Encefálica/diagnóstico , Hipoxia-Isquemia Encefálica/etiología , Hipoxia-Isquemia Encefálica/terapia , Recién Nacido , Enfermería Neonatal/métodos , Salas Cuna en Hospital , Medición de Riesgo/métodos , Gestión de Riesgos
10.
Crit Care Med ; 45(2): 171-178, 2017 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-27861180

RESUMEN

OBJECTIVES: To track compliance by an interprofessional team with the Awakening and Breathing Coordination, Choice of drugs, Delirium monitoring and management, Early mobility, and Family engagement (ABCDEF) bundle in implementing the Pain, Agitation, and Delirium guidelines. The aim was to study the association between ABCDEF bundle compliance and outcomes including hospital survival and delirium-free and coma-free days in community hospitals. DESIGN: A prospective cohort quality improvement initiative involving ICU patients. SETTING: Seven community hospitals within California's Sutter Health System. PATIENTS: Ventilated and nonventilated general medical and surgical ICU patients enrolled between January 1, 2014, and December 31, 2014. MEASUREMENTS AND MAIN RESULTS: Total and partial bundle compliance were measured daily. Random effects regression was used to determine the association between ABCDEF bundle compliance accounting for total compliance (all or none) or for partial compliance ("dose" or number of bundle elements used) and outcomes of hospital survival and delirium-free and coma-free days, after adjusting for age, severity of illness, and presence of mechanical ventilation. Of 6,064 patients, a total of 586 (9.7%) died before hospital discharge. For every 10% increase in total bundle compliance, patients had a 7% higher odds of hospital survival (odds ratio, 1.07; 95% CI, 1.04-1.11; p < 0.001). Likewise, for every 10% increase in partial bundle compliance, patients had a 15% higher hospital survival (odds ratio, 1.15; 95% CI, 1.09-1.22; p < 0.001). These results were even more striking (12% and 23% higher odds of survival per 10% increase in bundle compliance, respectively, p < 0.001) in a sensitivity analysis removing ICU patients identified as receiving palliative care. Patients experienced more days alive and free of delirium and coma with both total bundle compliance (incident rate ratio, 1.02; 95% CI, 1.01-1.04; p = 0.004) and partial bundle compliance (incident rate ratio, 1.15; 95% CI, 1.09-1.22; p < 0.001). CONCLUSIONS: The evidence-based ABCDEF bundle was successfully implemented in seven community hospital ICUs using an interprofessional team model to operationalize the Pain, Agitation, and Delirium guidelines. Higher bundle compliance was independently associated with improved survival and more days free of delirium and coma after adjusting for age, severity of illness, and presence of mechanical ventilation.


Asunto(s)
Delirio/prevención & control , Adhesión a Directriz/estadística & datos numéricos , Hospitales Comunitarios/estadística & datos numéricos , Unidades de Cuidados Intensivos/estadística & datos numéricos , Paquetes de Atención al Paciente/métodos , California , Coma/prevención & control , Cuidados Críticos/métodos , Cuidados Críticos/normas , Femenino , Mortalidad Hospitalaria , Hospitales Comunitarios/métodos , Humanos , Masculino , Persona de Mediana Edad , Paquetes de Atención al Paciente/mortalidad , Estudios Prospectivos , Mejoramiento de la Calidad , Resultado del Tratamiento
11.
J Thromb Thrombolysis ; 43(3): 380-386, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-27878507

RESUMEN

To report the impact of an inpatient anticoagulation stewardship program at a community hospital to promote optimal anticoagulant use. The anticoagulation team (ACT) stewardship program consists of two clinical pharmacists and hematologists to provide oversight of anticoagulants, high cost reversal agents including prothrombin complex concentrate (PCC, Kcentra™), and heparin-induced thrombocytopenia (HIT) management. Intervention data and number of charts reviewed were collected. Average cost avoidance data was applied to ACT interventions to estimate cost savings. The PCC analysis was conducted via retrospective chart review during the pre-intervention period. Prospective monitoring continued in the post-intervention period to determine the percentage of PCC use within the institution's guidelines or approved by ACT or hematology. A total of 19,445 patient charts were reviewed, and 1930 (10%) contained stewardship opportunity. Of the interventions, 71% were provided to the medical service and 22% to surgical services with acceptance rates of 91 and 83%, respectively. Intervention cost-avoidance calculated to be $694,217. Regarding HIT interventions, 52% of interventions involved pharmacokinetic/pharmacodynamics optimization in 18 patients with suspected or confirmed HIT. Regarding PCC use, 55.8% of PCC orders were considered inappropriate in the pre-invention period versus 2.6% post-intervention. Appropriate PCC doses per month post-intervention were consistent with pre-intervention doses (7.67 vs. 6.73, respectively). The projected annual PCC cost savings is $385,473. The overall estimated financial impact of ACT is $799,690 saved. Implementation of an anticoagulation stewardship program reduced costs and improved clinical outcomes. It is also expected that anticoagulant optimization and provider education improved overall safety.


Asunto(s)
Anticoagulantes/uso terapéutico , Hospitales de Enseñanza/métodos , Factores de Coagulación Sanguínea/administración & dosificación , Factores de Coagulación Sanguínea/economía , Factores de Coagulación Sanguínea/uso terapéutico , Costos y Análisis de Costo , Manejo de la Enfermedad , Femenino , Hematología/educación , Hospitales Comunitarios/economía , Hospitales Comunitarios/métodos , Hospitales Comunitarios/organización & administración , Hospitales de Enseñanza/economía , Hospitales de Enseñanza/organización & administración , Humanos , Masculino , Farmacéuticos , Estudios Prospectivos , Estudios Retrospectivos , Trombocitopenia/inducido químicamente , Trombocitopenia/tratamiento farmacológico , Trombocitopenia/economía
12.
J Infect Chemother ; 23(10): 692-697, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28807755

RESUMEN

We hypothesized that cases of uncomplicated cystitis treated in a Urology Department would display higher antimicrobial susceptibility than those reported by the hospital antibiogram. This would suggest narrow spectrum antibiotics could still be an effective treatment for uncomplicated cystitis despite this era of antimicrobial resistance. The objective of this study was thus to evaluate the rates of antimicrobial susceptibility of isolates cultured from uncomplicated cystitis cases that presented to the Urology Department of a community hospital in Japan. We evaluated the efficacy of cefaclor, a narrow spectrum antibiotic, for uncomplicated cystitis. We further compared the rates of antimicrobial susceptibility of isolates from uncomplicated cystitis cases to those reported in a hospital-wide antibiogram. A retrospective chart review was performed of patients diagnosed with uncomplicated cystitis in the Urology Department. The patients were mainly treated orally by cefaclor at 750 mg/day for seven days. Significantly greater susceptibilities to cefazolin (87.0% vs 65.7%), trimethoprim-sulfamethoxazole (89.4% vs 79.1%) and levofloxacin (84.6% vs 66.9%) were observed in a cystitis antibiogram for Escherichia coli compared with a hospital-wide antibiogram. The clinical efficacy of cefaclor for acute cystitis was also demonstrated. The greater susceptibility of Escherichia coli to antimicrobials observed in this study supports the hypothesis that antimicrobial susceptibility rates in uncomplicated cystitis cases that present to the Urology Department would be greater than those reported in the hospital antibiogram. Therefore, uncomplicated acute cystitis can be treated by narrow spectrum antibiotics such as cefaclor even in this ''antimicrobial resistance era''.


Asunto(s)
Antiinfecciosos/uso terapéutico , Cistitis/tratamiento farmacológico , Escherichia coli/efectos de los fármacos , Escherichia coli/aislamiento & purificación , Enfermedad Aguda , Adulto , Anciano , Anciano de 80 o más Años , Cistitis/microbiología , Femenino , Hospitales Comunitarios/métodos , Humanos , Japón , Levofloxacino/uso terapéutico , Pruebas de Sensibilidad Microbiana/métodos , Persona de Mediana Edad , Estudios Retrospectivos , Resultado del Tratamiento , Combinación Trimetoprim y Sulfametoxazol/uso terapéutico , Urología/métodos , Adulto Joven
13.
Intern Med J ; 46(3): 295-300, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-26549020

RESUMEN

BACKGROUND: Since Hinton first published his observations on the distress of patients dying on a medical ward in 1963, there has been increasing awareness of the palliative care needs in patients who have non malignant diseases. Patients with advanced chronic obstructive pulmonary disease (COPD) are known to have comparable symptom burden to lung cancer patients and are more likely receive invasive treatment at the end of life than patients with end stage lung cancer. They are also less likely to receive hospice services, and the benefit of such programmes in this key group of patients remain largely unknown, in particular what effect hospice programmes have on hospitalisation. AIMS: (i) To examine any effect of community hospice programmes on hospitalisation in patients with advanced COPD. (ii) To identify any association between utilisation of specific hospice services with hospitalisation. (iii) To describe key peri-mortem outcomes. METHODS: This was a retrospective study of consecutive patients with COPD admitted into community hospice programmes in the greater Wellington region, New Zealand between 1 October 2007 and 31 October 2013. RESULTS: A mean decrease of 2.375 (median decrease of 2; 95% confidence interval 1, 3) hospital admissions over a 12-month period was found after admission into hospice programme (P < 0.0005). CONCLUSION: Community hospice programmes may be associated with reduction in hospitalisation in patients with advanced COPD.


Asunto(s)
Cuidados Paliativos al Final de la Vida/tendencias , Hospitalización/tendencias , Hospitales Comunitarios/tendencias , Enfermedad Pulmonar Obstructiva Crónica/epidemiología , Enfermedad Pulmonar Obstructiva Crónica/terapia , Anciano , Anciano de 80 o más Años , Femenino , Cuidados Paliativos al Final de la Vida/métodos , Hospitales Comunitarios/métodos , Humanos , Masculino , Persona de Mediana Edad , Nueva Zelanda/epidemiología , Enfermedad Pulmonar Obstructiva Crónica/diagnóstico , Estudios Retrospectivos
14.
Ann Emerg Med ; 61(6): 654-60, 2013 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22771203

RESUMEN

STUDY OBJECTIVE: We identify hospital-level factors from the administrative perspective that affect the availability and delivery of palliative care services in the emergency department (ED). METHODS: Semistructured interviews were conducted with 14 key informants, including hospital executives, ED directors, and palliative care directors at a tertiary care center, a public hospital, and a community hospital. The discussions were digitally recorded and transcribed to conduct a thematic analysis using grounded theory. A coding scheme was iteratively developed to subsequently identify themes and subthemes that emerged from the interviews. RESULTS: Barriers to integrating palliative care and emergency medicine from the administrative perspective include the ED culture of aggressive care, limited knowledge, palliative care staffing, and medicolegal concerns. Incentives to the delivery of palliative care in the ED from these key informants' perspective include improved patient and family satisfaction, opportunities to provide meaningful care to patients, decreased costs of care for admitted patients, and avoidance of unnecessary admissions to more intensive hospital settings, such as the ICU, for patients who have little likelihood of benefit. CONCLUSION: Though hospital administration at 3 urban hospitals on the East coast has great interest in integrating palliative care and emergency medicine to improve quality of care, patient and family satisfaction, and decrease length of stay for admitted patients, palliative care staffing, medicolegal concerns, and logistic issues need to be addressed.


Asunto(s)
Actitud del Personal de Salud , Servicio de Urgencia en Hospital , Administradores de Hospital , Cuidados Paliativos , Servicio de Urgencia en Hospital/legislación & jurisprudencia , Servicio de Urgencia en Hospital/organización & administración , Accesibilidad a los Servicios de Salud/organización & administración , Hospitales Comunitarios/métodos , Hospitales Comunitarios/organización & administración , Hospitales Públicos/métodos , Hospitales Públicos/organización & administración , Humanos , Entrevistas como Asunto , Cuidados Paliativos/legislación & jurisprudencia , Cuidados Paliativos/métodos , Cuidados Paliativos/organización & administración , Centros de Atención Terciaria/organización & administración , Estados Unidos
15.
J Clin Pharm Ther ; 38(5): 401-4, 2013 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-23845154

RESUMEN

WHAT IS KNOWN AND OBJECTIVES: Antimicrobial stewardship programmes (ASPs) have been shown to decrease antimicrobial resistance, reduce hospital-acquired infections and decrease overall antimicrobial expenditures. At St. Joseph Medical Center in Bellingham, WA, a thrice-weekly ASP was initiated in 2010 with the goals of decreasing carbapenem, fluoroquinolone and vancomycin use and tailoring duration of therapy. METHODS: Antibiotic use per 1000 patient-days and carbapenem, fluoroquinolone and vancomycin use were evaluated pre- and post-implementation of the ASP. Total antimicrobial expenditures were evaluated for the 3 years prior to ASP implementation and three years following implementation. RESULTS AND DISCUSSION: Antimicrobial days of therapy per 1000 patient-days declined by 6·4% after implementation of our ASP. There was a 37% reduction in total antimicrobial expenditures after implementation. Carbapenems, vancomycin and levofloxacin use decreased considerably. Ciprofloxacin use increased during the same time period. WHAT IS NEW AND CONCLUSION: A thrice-weekly, pharmacist-driven ASP can decrease antimicrobial expenditure, shorten duration of therapy and decrease the utilization of carbapenems, vancomycin and levofloxacin.


Asunto(s)
Antibacterianos/administración & dosificación , Antibacterianos/economía , Carbapenémicos/administración & dosificación , Infección Hospitalaria/prevención & control , Farmacorresistencia Bacteriana , Fluoroquinolonas/administración & dosificación , Hospitales Comunitarios/economía , Hospitales Comunitarios/métodos , Hospitales Comunitarios/organización & administración , Humanos , Estudios Retrospectivos , Vancomicina/administración & dosificación
16.
Can Assoc Radiol J ; 64(3): 208-12, 2013 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-23267521

RESUMEN

BACKGROUND: It is important for physicians to be aware of the radiation doses as well as the risks associated with diagnostic imaging procedures that they are ordering. METHODS: A survey was administered to patients, medical students, and referring physicians from a number of specialties to determine background knowledge regarding radiation exposure and risk associated with commonly ordered medical imaging tests. RESULTS: A total of 127 patients, 32 referring physicians, and 30 medical students completed the survey. The majority of patients (92%) were not informed of the radiation risks associated with tests that they were scheduled to receive and had false perceptions about the use of radiation and its associated risks. Physicians and medical students had misconceptions about the use of ionizing radiation in a number of radiologic examinations; for example, 25% and 43% of physicians and medical students, respectively, were unaware that interventional procedures used ionizing radiation, and 28% of physicians were unaware that mammography used ionizing radiation. Computed tomographies and barium studies were thought to be associated with the least ionizing radiation among physicians. CONCLUSION: There is a need for educating the public, medical students, and referring physicians about radiation exposure and associated risk so that (1) patients receiving multiple medical imaging tests are aware of the radiation that they are receiving and (2) physicians and future physicians will make informed decisions when ordering such tests to limit the amount of radiation that patients receive and to promote informed consent among patients.


Asunto(s)
Competencia Clínica/estadística & datos numéricos , Diagnóstico por Imagen/efectos adversos , Conocimientos, Actitudes y Práctica en Salud , Médicos/estadística & datos numéricos , Dosis de Radiación , Estudiantes de Medicina/estadística & datos numéricos , Actitud del Personal de Salud , Canadá , Estudios Transversales , Femenino , Encuestas de Atención de la Salud/métodos , Encuestas de Atención de la Salud/estadística & datos numéricos , Hospitales Comunitarios/métodos , Humanos , Masculino , Seguridad del Paciente/estadística & datos numéricos , Personal de Hospital/estadística & datos numéricos , Traumatismos por Radiación , Derivación y Consulta , Medición de Riesgo/métodos , Medición de Riesgo/estadística & datos numéricos , Atención Terciaria de Salud/métodos
17.
Aust Fam Physician ; 41(1-2): 73-6, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22276291

RESUMEN

BACKGROUND: The impact of type 2 diabetes is severe in Aboriginal and Torres Strait Islander people. The Fitzroy Valley, a remote region of the Kimberley in Western Australia, has a high population of Indigenous Australians. An effective community partnership has been formed between the local hospital, the population health service and local health services. OBJECTIVE: This article describes the evaluation of a new model of partnership care using an audit cycle. Results Statistically significant improvements in foot examination, body mass index, urine albumin creatinine ratio, total cholesterol, triglycerides and visual acuity measurements were observed. Significant increases in the proportion of patients achieving cholesterol and triglycerides therapeutic targets occurred. Most other outcome indicators demonstrated a nonsignificant improvement, which may be due to the short time interval in the audit for potential change. CONCLUSION: A dedicated chronic disease team and a clinical information system to coordinate culturally appropriate, multidisciplinary chronic disease care enables effective management of chronic diseases such as type 2 diabetes.


Asunto(s)
Centros Comunitarios de Salud , Diabetes Mellitus Tipo 2/terapia , Manejo de la Enfermedad , Servicios de Salud del Indígena , Hospitales Comunitarios/métodos , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Nativos de Hawái y Otras Islas del Pacífico , Resultado del Tratamiento , Australia Occidental
18.
J La State Med Soc ; 164(1): 38-42, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22533113

RESUMEN

OBJECTIVE: The objective of our study was to investigate the indications for breast magnetic resonance imaging, or MRI, in our community hospital, determine how many probably benign MRI findings were malignant at follow-up, determine how many cancers were identified by MRI in screening patients, and evaluate the utility of MRI for surgical planning and problem-solving. MATERIALS AND METHODS: Five hundred twenty-eight contrast-enhanced MRI's of the breast in 434 patients were retrospectively reviewed. MRI images/reports were compared to surgical pathology reports and the results of follow-up studies. RESULTS: Screening was the most common indication for breast MRI in our patient population. Five percent of findings termed "probably benign" on MRI proved to be malignant at follow-up. Eight malignancies were detected in six of 202 screened patients. Ten malignancies were diagnosed in 66 patients referred to MRI for problem-solving. In two of 74 patients with known breast cancer, an unsuspected ipsilateral cancer was identified on MRI. CONCLUSION: MRI proved useful in the community hospital setting for screening high-risk patients and problem-solving. The rate of malignancy in probably benign MRI findings was higher than the corresponding rate in mammography. The detection of additional ipsilateral and contralateral cancers in pre-operative patients with known breast cancer was not as high as expected, based on prior studies.


Asunto(s)
Neoplasias de la Mama , Mama/patología , Detección Precoz del Cáncer , Hospitales Comunitarios , Imagen por Resonancia Magnética , Adulto , Anciano , Anciano de 80 o más Años , Mama/cirugía , Neoplasias de la Mama/diagnóstico , Neoplasias de la Mama/cirugía , Manejo de la Enfermedad , Detección Precoz del Cáncer/métodos , Detección Precoz del Cáncer/normas , Femenino , Hospitales Comunitarios/métodos , Hospitales Comunitarios/estadística & datos numéricos , Humanos , Imagen por Resonancia Magnética/métodos , Imagen por Resonancia Magnética/normas , Registros Médicos Orientados a Problemas/estadística & datos numéricos , Persona de Mediana Edad , Selección de Paciente , Estudios Retrospectivos
20.
J Trauma Acute Care Surg ; 92(1): 38-43, 2022 01 01.
Artículo en Inglés | MEDLINE | ID: mdl-34670959

RESUMEN

BACKGROUND: Regionalization of emergency general surgery (EGS) has primarily focused on expediting care of high acuity patients through interfacility transfers. In contrast, triaging low-risk patients to a nondesignated trauma facility has not been evaluated. This study evaluates a 16-month experience of a five-surgeon team triaging EGS patients at a tertiary care, Level I trauma center (TC) to an affiliated community hospital 1.3 miles away. METHODS: All EGS patients who presented to the Level I TC emergency department from January 2020 to April 2021 were analyzed. Patients were screened by EGS surgeons covering both facilities for transfer appropriateness including hemodynamics, resource need, and comorbidities. Patients were retrospectively evaluated for disposition, diagnosis, comorbidities, length of stay, surgical intervention, and 30-day mortality and readmission. RESULTS: Of 987 patients reviewed, 31.5% were transferred to the affiliated community hospital, 16.1% were discharged home from the emergency department, and 52.4% were admitted to the Level I TC. Common diagnoses were biliary disease (16.8%), bowel obstruction (15.7%), and appendicitis (14.3%). Compared with Level I TC admissions, Charlson Comorbidity Index was lower (1.89 vs. 4.45, p < 0.001) and length of stay was shorter (2.23 days vs. 5.49 days, p < 0.001) for transfers. Transfers had a higher rate of surgery (67.5% vs. 50.1%, p < 0.001) and lower readmission and mortality (8.4% vs. 15.3%, p = 0.004; 0.6% vs. 5.0%, p < 0.001). Reasons not to transfer were emergency evaluation, comorbidity burden, operating room availability, and established care. No transfers required transfer back to higher care (under-triage). Bed days saved at the Level I TC were 693 (591 inpatients). Total operating room minutes saved were 24,008 (16,919, between 7:00 am and 5:00 pm). CONCLUSION: Transfer of appropriate patients maintains high quality care and outcomes, while improving operating room and bed capacity and resource utilization at a tertiary care, Level I TC. Emergency general surgery regionalization should consider triage of both high-risk and low-risk patients. LEVEL OF EVIDENCE: Prospective comparative cohort study, Level II.


Asunto(s)
Cuidados Críticos , Cirugía General/métodos , Transferencia de Pacientes , Ajuste de Riesgo , Triaje , Adulto , Cuidados Críticos/métodos , Cuidados Críticos/normas , Servicio de Urgencia en Hospital/estadística & datos numéricos , Femenino , Hospitales Comunitarios/métodos , Hospitales Comunitarios/organización & administración , Humanos , Masculino , Persona de Mediana Edad , Evaluación de Necesidades , Evaluación de Resultado en la Atención de Salud , Selección de Paciente , Transferencia de Pacientes/métodos , Transferencia de Pacientes/normas , Transferencia de Pacientes/estadística & datos numéricos , Mejoramiento de la Calidad/organización & administración , Ajuste de Riesgo/métodos , Ajuste de Riesgo/normas , Atención Terciaria de Salud/estadística & datos numéricos , Centros Traumatológicos/estadística & datos numéricos , Triaje/métodos , Triaje/normas , Estados Unidos/epidemiología
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