Detalhe da pesquisa
1.
Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors.
Bioorg Med Chem Lett
; 25(7): 1592-6, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728416
2.
Discovery of pyrrolo-benzo-1,4-diazines as potent Na(v)1.7 sodium channel blockers.
Bioorg Med Chem Lett
; 24(17): 4110-3, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25113934
3.
Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent.
J Med Chem
; 51(7): 2302-6, 2008 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18314943
4.
Dihydropyrrolopyrazole transforming growth factor-beta type I receptor kinase domain inhibitors: a novel benzimidazole series with selectivity versus transforming growth factor-beta type II receptor kinase and mixed lineage kinase-7.
J Med Chem
; 49(6): 2138-42, 2006 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-16539403
5.
Chromium(0)-promoted multicomponent cycloaddition of tethered diynes with cyclic trienes: application to the total synthesis of 9-epi-pentalenic acid.
J Org Chem
; 69(20): 6751-60, 2004 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15387599