Detalhe da pesquisa
1.
A Machine Learning-Based Image Segmentation Method to Quantify In Vitro Osteoclast Culture Endpoints.
Calcif Tissue Int
; 113(4): 437-448, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37566229
2.
Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture.
Regul Toxicol Pharmacol
; 115: 104697, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32590049
3.
Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.
J Biol Chem
; 293(31): 12149-12166, 2018 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925589
4.
Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.
J Biol Chem
; 287(32): 26464-77, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22696217
5.
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.
Cell Stem Cell
; 29(4): 528-544.e9, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35276096
6.
Osteocyte mechanosensing following short-term and long-term treatment with sclerostin antibody.
Bone
; 149: 115967, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33892178
7.
Recombinant sclerostin inhibits bone formation in vitro and in a mouse model of sclerosteosis.
J Orthop Translat
; 29: 134-142, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34249611
8.
Sclerostin antibody increases trabecular bone and bone mechanical properties by increasing osteoblast activity damaged by whole-body irradiation in mice.
Bone
; 147: 115918, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737193
9.
Sclerostin Downregulation Globally by Naturally Occurring Genetic Variants, or Locally in Atherosclerotic Plaques, Does Not Associate With Cardiovascular Events in Humans.
J Bone Miner Res
; 36(7): 1326-1339, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784435
10.
Sclerostin antibody stimulates periodontal regeneration in large alveolar bone defects.
Sci Rep
; 10(1): 16217, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33004873
11.
Novel actions of sclerostin on bone.
J Mol Endocrinol
; 62(2): R167-R185, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30532996
12.
Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins.
Nephron
; 142(4): 328-350, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048591
13.
Genetic data do not provide evidence that lower sclerostin is associated with increased risk of atherosclerosis: comment on the article by Zheng et al.
Arthritis Rheumatol
; 2023 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37942677
14.
Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists.
Bone
; 107: 93-103, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29129759
15.
Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ.
Sci Rep
; 7(1): 9963, 2017 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855577
16.
An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix.
Biol Open
; 6(10): 1423-1433, 2017 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29032370
17.
Publisher Correction: Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ.
Sci Rep
; 7(1): 18111, 2017 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269854
18.
Analysis of endogenous S1P and LPA receptor expression in CHO-K1 cells.
Gene
; 350(1): 59-63, 2005 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15780969
19.
Functional inhibition of ß-catenin-mediated Wnt signaling by intracellular VHH antibodies.
MAbs
; 7(1): 180-91, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25524068
20.
Resonance assignment and secondary structure determination of full length human Dickkopf 4 (hDkk4), a secreted, disulphide-rich Wnt inhibitor protein.
Biomol NMR Assign
; 9(1): 147-51, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24816897