Detalhe da pesquisa
1.
HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts.
J Lipid Res
; 62: 100114, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34481829
2.
Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid.
J Biol Chem
; 295(23): 8017-8035, 2020 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32354745
3.
Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.
Mol Cell Proteomics
; 16(11): 1938-1957, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28860124
4.
Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells.
J Lipid Res
; 58(4): 695-708, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193631
5.
Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis.
Mol Cell Proteomics
; 14(7): 1734-49, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25873482
6.
Adding hydrophobicity or positive charges to the cytosolic half of the α-synuclein 3-11 helix increases membrane association and S129 phosphorylation.
FEBS Lett
; 598(2): 210-219, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37989349
7.
Analysis of DHHC acyltransferases implies overlapping substrate specificity and a two-step reaction mechanism.
Traffic
; 10(8): 1061-73, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19453970
8.
Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process.
Nat Commun
; 10(1): 5052, 2019 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699992
9.
2-Hydroxypropyl-ß-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1864(10): 1545-1561, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31051283
10.
NPC1/NPC2 function as a tag team duo to mobilize cholesterol.
Proc Natl Acad Sci U S A
; 105(40): 15223-4, 2008 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18832164
11.
Palmitoylation determines the function of Vac8 at the yeast vacuole.
J Cell Sci
; 119(Pt 12): 2477-85, 2006 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16720644
12.
The DHHC protein Pfa3 affects vacuole-associated palmitoylation of the fusion factor Vac8.
Proc Natl Acad Sci U S A
; 102(48): 17366-71, 2005 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16301533