ABC transporters in the protozoan parasite Leishmania
Int. microbiol
; 4(3): 159-166, sept. 2001. ilus
Article
en En
| IBECS
| ID: ibc-23248
Biblioteca responsable:
ES1.1
Ubicación: ES1.1 - BNCS
ABSTRACT
ATP-binding cassette (ABC) transporters constitute one of the biggest and most conserved protein families in the evolutionary scale. Many of them are of enormous clinical relevance, due to their relationship with genetic diseases and drug resistance during the treatment of cancer and infectious diseases. Leishmaniasis is a major and globally widespread group of parasitic diseases, whose treatment has been complicated by the expansion of resistance to conventional drugs. Here, we review the current knowledge about ABC transporters in Leishmania spp, with special attention to their relationship with the drug-resistance phenotype (AU)
RESUMEN
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Colección:
06-national
/
ES
Banco de datos:
IBECS
Asunto principal:
Leishmaniasis
/
Transportadoras de Casetes de Unión a ATP
/
Leishmania
Límite:
Animals
Idioma:
En
Revista:
Int. microbiol
Año:
2001
Tipo del documento:
Article