Chronic social stress during puberty enhances tyrosine hydroxylase immunoreactivity within the limbic system in golden hamsters.
Brain Res
; 933(2): 139-43, 2002 Apr 19.
Article
en En
| MEDLINE
| ID: mdl-11931858
ABSTRACT
The present study was carried out to determine the effects of chronic exposure to social stress during puberty on the dopamine system in male golden hamsters. Experimental animals were socially subjugated between postnatal days 28 (P28) and 42. All animals were sacrificed on P46 and their brains processed for immunocytochemistry to tyrosine hydroxylase (TH). A large increase in the number of TH-immunoreactive (TH-ir) neurons was noted within the posterior portion of the medial amygdaloid nucleus and the posterior portion of the medial division of the bed nucleus of the stria terminalis in subjugated animals as compared to controls. This effect appeared to be site-specific as no difference was seen between groups in the periventricular nucleus, another steroid receptor-rich area. The data suggest that these dopamine neurons may play an important role in the behavioral changes associated with chronic social stress during puberty.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Conducta Social
/
Estrés Psicológico
/
Conducta Animal
/
Dopamina
/
Regulación hacia Arriba
/
Sistema Límbico
/
Vías Nerviosas
Límite:
Animals
Idioma:
En
Revista:
Brain Res
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos