Effect of Ginkgo biloba extract EGb 761 on the nonspecific and humoral immune responses in a hypothalamic-pituitary-adrenal axis activation model.
Int Immunopharmacol
; 4(9): 1217-22, 2004 Sep.
Article
en En
| MEDLINE
| ID: mdl-15251117
ABSTRACT
We evaluated the immune response of healthy control and stressed Wistar rats submitted to hypothalamic-pituitary-adrenal (HPA) axis activation. Rats were treated with Ginkgo biloba extract (EGb 761) orally (100 mg/kg per day for 7 days). EGb 761 stimulated the digestion index of peritoneal and alveolar macrophages (PM and AM) of stressed rats. Likewise, the cellular immune response measured using the delayed-type hypersensitivity response to sheep red blood cells (SRBC) and the humoral immune response (measured through an anti-SRBC response), were also restored in stressed rats. Thus, this G. biloba extract possesses immunostimulatory activity in addition to its broad spectrum of pharmacological effects.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sistema Hipófiso-Suprarrenal
/
Extractos Vegetales
/
Adyuvantes Inmunológicos
/
Sistema Hipotálamo-Hipofisario
/
Formación de Anticuerpos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Int Immunopharmacol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
FARMACOLOGIA
Año:
2004
Tipo del documento:
Article
País de afiliación:
México