The impact of active intervention on the spread of penicillin-resistant Streptococcus pneumoniae in Swedish day-care centres.
Scand J Infect Dis
; 36(9): 629-35, 2004.
Article
en En
| MEDLINE
| ID: mdl-15370647
ABSTRACT
Policies for handling cases of penicillin-non-susceptible Streptococcus pneumoniae (PNSP) in day-care groups vary between different counties in Sweden. The aim of this study was to evaluate the epidemiological effect of excluding PNSP-carriers from children's day-care centres (DCC). We followed the incidence in 14 DCC groups with ongoing PNSP-spread, by repeated group screens until no further cases could be identified. All identified carriers were excluded from DCC attendance in study area A (Skåne region) while they remained in the group in study area B (Göteborg and örebro), according to local policies. The intervention effect was evaluated by comparing the number of additional cases after the baseline screen (start of the intervention period) between the 2 study areas. All PNSP-isolates were characterized by resistance pattern, serotype and pulse-field gel electrophoresis. The relative risk for children in DCCs without active intervention was 6.4 (95% CI 2.0-20.7). Each prevented case in area A can be estimated to have demanded the exclusion of 2 other children from day care for approximately 4 weeks each. The total cost-benefit outcome of this action has to be seen in the light of the local situation with regard to the population prevalence and the distribution of other risk factors.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones Neumocócicas
/
Resistencia a las Penicilinas
/
Portador Sano
/
Control de Enfermedades Transmisibles
/
Brotes de Enfermedades
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Scand J Infect Dis
Año:
2004
Tipo del documento:
Article
País de afiliación:
Suecia