[Cardiovascular effects of SERM].
Clin Calcium
; 14(10): 61-7, 2004 Oct.
Article
en Ja
| MEDLINE
| ID: mdl-15577133
ABSTRACT
Raloxifene has an estrogenic effect on the cardio-vascular system. In vascular endothelium, both clinical and basic studies show that raloxifene induces the synthesis and release of nitric oxide. In vascular smooth muscle, basic study shows that raloxifene attenuates the PDGF-induced cell proliferation by both induction of apoptosis and arrest of the cell cycle. We now await the results of currently ongoing prospective large scale randomized control trial, Raloxifene Use of The Heart.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Clorhidrato de Raloxifeno
/
Moduladores Selectivos de los Receptores de Estrógeno
Tipo de estudio:
Clinical_trials
Límite:
Humans
Idioma:
Ja
Revista:
Clin Calcium
Asunto de la revista:
METABOLISMO
Año:
2004
Tipo del documento:
Article